Reactivity | HuSpecies Glossary |
Applications | WB, IHC |
Clone | 2444A |
Clonality | Monoclonal |
Host | Rabbit |
Conjugate | mFluor Violet 450 SE |
Additional Information | Recombinant Monoclonal Antibody. |
Immunogen | This recombinant HIF-2 alpha/EPAS1 Antibody (2444A) is made to a partial recombinant human HIF-2 protein (amino acids 543-870) [UniProt Q99814] |
Isotype | IgG |
Clonality | Monoclonal |
Host | Rabbit |
Gene | EPAS1 |
Purity | Protein A or G purified |
Innovator's Reward | Test in a species/application not listed above to receive a full credit towards a future purchase. |
Dilutions |
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Application Notes | Optimal dilution of this antibody should be experimentally determined. |
Storage | Store at 4C in the dark. |
Buffer | 50mM Sodium Borate |
Preservative | 0.05% Sodium Azide |
Purity | Protein A or G purified |
Secondary Antibodies |
Isotype Controls |
Research Areas for HIF-2 alpha/EPAS1 Antibody (NBP2-76454MFV450)Find related products by research area.
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Breast cancer stem cells survive chemotherapy through S100A10-ANXA2-SPT6 interaction that epigenetically promotes OCT4-mediated stemness By Jamshed Arslan, Pharm D, PhDBreast cancer is the most common cancer among women that causes the greatest number of cancer-related deaths worldwide. After radiotherapy or cytotoxic chemotherapy like paclitax... Read full blog post. |
HIF-2 alpha: HIF1A's Homologue with Similar and Divergent Functions HIF-2 alpha is a member of the heterodimeric hypoxia-inducible factors/HIFs family (HIF-1, HIF-2, and HIF-3) which contains a common beta subunit but differ in their alpha subunits. Also called as EPAS1 or Mop2, HIF-2 alpha regulates cellular adapt... Read full blog post. |
HIF-2 alpha, Tumor Suppression and Cell Survival HIF-2 alpha is one subunit within the HIF-2 nuclear protein that regulates cellular responses to hypoxia (low oxygen tension conditions). Hydroxylation post-translational modifications on particular HIF residues target them for degradation. Luo, et al... Read full blog post. |
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Gene Symbol | EPAS1 |