Novus Biologicals products are now on bio-techne.com

Glutathione Reductase Antibody (6B4)

Images

 
Western Blot: Glutathione Reductase Antibody (6B4) [H00002936-M01] - Analysis of GSR expression in transfected 293T cell line by GSR monoclonal antibody (M01), clone 6B4.Lane 1: GSR transfected lysate(56.3 KDa).Lane 2: ...read more
Immunohistochemistry-Paraffin: Glutathione Reductase Antibody (6B4) [H00002936-M01] - Analysis of monoclonal antibody to GSR on formalin-fixed paraffin-embedded human salivary gland. Antibody concentration 6 ug/ml.
Western Blot: Glutathione Reductase Antibody (6B4) [H00002936-M01] - Analysis of GSR over-expressed 293 cell line, cotransfected with GSR Validated Chimera RNAi ( Cat # H00002936-R01V ) (Lane 2) or non-transfected ...read more
Western Blot: Glutathione Reductase Antibody (6B4) [H00002936-M01] - GSR monoclonal antibody (M01), clone 6B4 Analysis of GSR expression in IMR-32.
ELISA: Glutathione Reductase Antibody (6B4) [H00002936-M01] - Detection limit for recombinant GST tagged GSR is approximately 0.03ng/ml as a capture antibody.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ELISA, IHC, KD
Clone
6B4
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated

Order Details

Novus Biologicals is part of Bio-Techne

Shop this product on bio-techne.com

Glutathione Reductase Antibody (6B4) Summary

Description
Quality control test: Antibody Reactive Against Recombinant Protein.
Immunogen
GSR (NP_000628, 413 a.a. ~ 522 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. TVVFSHPPIGTVGLTEDEAIHKYGIENVKTYSTSFTPMYHAVTKRKTKCVMKMVCANKEEKVVGIHMQGLGCDEMLQGFAVAVKMGATKADFDNTVAIHPTSSEELVTLR
Localization
Cytoplasmic
Specificity
GSR - glutathione reductase
Isotype
IgG2a Kappa
Clonality
Monoclonal
Host
Mouse
Gene
GSR
Purity
IgG purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • ELISA
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Knockdown Validated
  • Western Blot 1:500
Application Notes
Antibody reactivity against cell lysate and recombinant protein for WB. It has also been used for IHC-P, RNAi Validation and ELISA.

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
In 1x PBS, pH 7.4
Preservative
No Preservative
Purity
IgG purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for Glutathione Reductase Antibody (6B4)

  • EC 1.8.1
  • EC 1.8.1.7
  • GLUR
  • Glutathione Reductase
  • glutathione reductase, mitochondrial
  • GR
  • GRase
  • GRD1
  • GSR
  • HEL-752
  • MGC78522

Background

Glutathione reductase (GR) is a member of pyridine nucleotide-disulfideoxidoreductases, which includes the closely related enzymes thioredoxin reductase, lipoamide dehydrogenase, trypanothione reductase and mercuric ion reductase. GR is a cytoplasmic flavoenzyme widely distributed in aerobic organisms. The dimeric protein is composed of two identical subunits, each containing 1 FAD and 1 redox-active disulfide/dithiol as components of the catalytic apparatus. It plays a role in maintaining glutathione(GSH) in its reduced form by catalyzing the reduction of glutathione disulfide (GSSG): GSSG + NADPH + H+ ->2GSH + NADP+. In mosteukaryotic cells, GR maintains the ratio of [GSH]/[GSSG], and participates in several vital functions such as the detoxification of reactive oxygen species as well as protein and DNA biosynthesis.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Customers Who Viewed This Item Also Viewed...

AF3398
Species: Hu, Mu, Rt
Applications: ICC, KO, Simple Western, WB
NB300-731
Species: Gp, Hu, Mu, Rb, Rt, Sh, Ye
Applications: B/N, ChIP, Flow, GS, ICC/IF, IHC, IHC-P, IP, WB
NBP2-24915
Species: Bv, Hu, Mu, Rt
Applications: IHC, IHC-P, WB
NBP1-86616
Species: Hu
Applications: IHC, IHC-P, WB
NBP2-58917
Species: Hu
Applications: IHC, IHC-P, WB
NBP2-16686
Species: Hu
Applications: ICC/IF, IHC, IHC-P, KO, WB
NBP2-49118
Species: Hu
Applications: IHC, IHC-P
NB100-236
Species: Hu, Mu
Applications: IB, IHC, IHC-Fr, IP, WB
NB100-1533
Species: Hu, Mu, Po, Rt, Sh
Applications: Flow, ICC/IF, IHC, IHC-P, PEP-ELISA, WB
NB300-562
Species: Ch, Hu, Mu, Rb, Rt, Sh
Applications: B/N, Flow, ICC/IF, IHC, IHC-P, WB
NB110-61574
Species: Bv, Gt, Hu, Mu, Sh
Applications: WB
NB100-116
Species: Hu, Mu, Pm, Rt
Applications: ChIP, ELISA, GS, IB, ICC/IF, IHC, IHC-Fr, IHC-P, IP, KD, PLA, Simple Western, WB
AF5415
Species: Hu
Applications: ICC, IHC, Simple Western, WB
MAB8930
Species: Hu
Applications: ICC, Simple Western, WB
7570-GH
Species: Hu
Applications: EnzAct
NB100-56603
Species: Ca, Hu, Mu, Pm, Rt
Applications: IHC, IHC-P, WB
H00002936-M01
Species: Hu
Applications: WB, ELISA, IHC, KD

Publications for Glutathione Reductase Antibody (H00002936-M01) (0)

There are no publications for Glutathione Reductase Antibody (H00002936-M01).
By submitting your publication information earn gift cards and discounts for future purchases.

Reviews for Glutathione Reductase Antibody (H00002936-M01) (0)

There are no reviews for Glutathione Reductase Antibody (H00002936-M01). By submitting a review you will receive an Amazon e-Gift Card or Novus Product Discount.
  • Review with no image -- $10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen
  • Review with an image -- $25/€18/£15/$25 CAD/¥150 Yuan/¥2500 Yen

Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

WB Video Protocol

FAQs for Glutathione Reductase Antibody (H00002936-M01) (0)

There are no specific FAQs related to this product. Read our general customer & technical service FAQs.

Secondary Antibodies

 

Isotype Controls

Additional Glutathione Reductase Products

Research Areas for Glutathione Reductase Antibody (H00002936-M01)

Find related products by research area.

Blogs on Glutathione Reductase

There are no specific blogs for Glutathione Reductase, but you can read our latest blog posts.
Read our latest blog and use the new citation tool on bio-techne.com

Customers Who Bought This Also Bought

Contact Information

Product PDFs

Calculators

Concentration Calculator

The concentration calculator allows you to quickly calculate the volume, mass or concentration of your vial. Simply enter your mass, volume, or concentration values for your reagent and the calculator will determine the rest.

=
÷

Review this Product

Be the first to review our Glutathione Reductase Antibody (6B4) and receive a gift card or discount.

Bioinformatics

Gene Symbol GSR
Entrez
OMIM
Uniprot