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GAB3 Antibody

Images

 
Western Blot: GAB3 Antibody [NBP1-86111] - Lane 1: Marker [kDa] 230, 130, 95, 72, 56, 36, 28, 17, 11. Lane 2: Human cell line RT-4. Lane 3: Human cell line U-251MG sp. Lane 4: Human plasma (IgG/HSA depleted). Lane ...read more
Immunohistochemistry-Paraffin: GAB3 Antibody [NBP1-86111] - Staining of human prostate shows weak cytoplasmic positivity in smooth muscle cells.
Immunohistochemistry-Paraffin: GAB3 Antibody [NBP1-86111] - Staining of human lung shows moderate membranous positivity in macrophages.
Immunohistochemistry-Paraffin: GAB3 Antibody [NBP1-86111] - Staining of human testis shows weak cytoplasmic positivity in Leydig cells.
Immunohistochemistry-Paraffin: GAB3 Antibody [NBP1-86111] - Staining of human kidney shows moderate cytoplasmic positivity in cells in tubules.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

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GAB3 Antibody Summary

Immunogen
This antibody was developed against Recombinant Protein corresponding to amino acids: CTLVPRRISLSGLDNMRTWKADVEGQSLRHRDKRLSLNLPCRFSPMYPTASASIEDSYVPMSPQAGASGLGPHCSPDDYIPMNSGSISSPLPELPANLEPPPVNRDLKPQRKSRPPPLDLRNLSIIREHASLTRTRTVPCSRTSF
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
GAB3
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:200 - 1:500
  • Immunohistochemistry-Paraffin 1:200 - 1:500
  • Western Blot 0.04-0.4 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Control Peptide
GAB3 Protein (NBP1-86111PEP)

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for GAB3 Antibody

  • DOS/Gab family member 3
  • Gab3 scaffolding protein
  • GAB3
  • GRB2-associated binder 3
  • GRB2-associated binding protein 3
  • GRB2-associated-binding protein 3
  • Growth factor receptor bound protein 2-associated protein 3

Background

The GAB3 gene is a member of the GRB2-associated binding protein gene family. These proteins are scaffolding/docking proteins that are involved in several growth factor and cytokine signaling pathways, and they contain a pleckstrin homology domain, and bind S

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol GAB3