Immunohistochemistry-Paraffin: Fc epsilon RI Antibody (AER-37) [NBP1-43278] - Staining of human mast cell in human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced ...read more
Flow Cytometry: Fc epsilon RI Antibody (AER-37) [NBP1-43278] - Analysis using the FITC conjugate of NBP1-43278. Staining of normal human peripheral blood cells with Anti-Human IgE PE and Mouse IgG2b K Isotype Control ...read more
Flow Cytometry: Fc epsilon RI Antibody (AER-37) [NBP1-43278] - Staining of normal human peripheral blood cells with Mouse IgG2b kappa Isotype Control Purified (green histogram) or Anti-Human Fc epsilon Receptor I a ...read more
The AER-37 antibody has been tested by flow cytometric analysis of peripheral blood leukocytes. This can be used at less than or equal to 1 ug per test. Cell number should be determined empirically but can range from 10^5to 10^8cells/test.
Use in Human reported in scientific literature (PMID:33741501).
Packaging, Storage & Formulations
Storage
Store at 4C. Do not freeze.
Buffer
PBS (pH 7.2)
Preservative
0.09% Sodium Azide
Concentration
0.5 mg/ml
Purity
Protein A or G purified
Alternate Names for Fc epsilon RI Antibody (AER-37) - BSA Free
alpha polypeptide
Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide
Fc-epsilon RI-alpha
FcERI
high affinity immunoglobulin epsilon receptor alpha-subunit
high affinity immunoglobulin epsilon receptor subunit alpha
high-affinity, of mast cells, alpha polypeptide
Background
The AER-37 monoclonal antibody reacts with the Fc epsilon RI alpha subunit, an IgE-binding subunit lacking signal-transducing ability. Fc epsilon RI alpha is expressed on mast and basophil cells and is upregulated by the presence of IgE. Fc epsilon RI alpha forms a tetrameric complex with one beta and two gamma subunits. The beta and gamma subunits possess immunoreceptor tyrosine-based activation motifs (ITAM). The Fc epsilon RI complex plays an important role in triggering IgE-mediated allergic reactions.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
The concentration calculator allows you to quickly calculate the volume, mass or concentration of your vial. Simply enter your mass, volume, or concentration values for your reagent and the calculator will determine the rest.
=
÷
Review this Product
Be the first to review our Fc epsilon RI Antibody (AER-37) - BSA Free and receive a gift card or discount.