IgE Antibody (1E7)

IgE is typically the least abundant isotype - blood serum IgE levels in a normal ("non-atopic") individual are ~150 ng/ml, compared to 10 mg/ml for the IgGs - it is capable of triggering the most powerful immune reactions. Most of our knowledge of IgE has come from research into the mechanism of a form of allergy known as type 1 hypersensitivity. There is much speculation into what physiological benefits IgE contributes, and so far, circumstantial evidence in animal models and statistical population trends have hinted that IgE may be beneficial in fighting gut parasites such as Schistosoma mansoni, but this has not been conclusively proven in humans. IgE may play an important role in the immune system's recognition of cancer, in which the stimulation of a strong cytotoxic response against cells displaying only small amounts of early cancer markers would be beneficial. IgE may be an important target in treatments for allergy and asthma.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 1 confirmed species: Human.

We have publications tested in 2 applications: ELISA, WB.

Showing Publications 1 - 5 of 5.

Publications using NBP3-11412	Applications	Species
Yamaki K, Egi T, Segawa K et al. Co-induced allergic response to an unrelated allergen exacerbates imiquimod-induced psoriasis in mice Biological & pharmaceutical bulletin 2023-08-18 [PMID: 37599076]
Huang Z, Jiang Y, Li H et al. Effect of glycation derived from ?-dicarbonyl compounds on the in vitro digestibility of ovalbumin: Tracing of advanced glycation end-products and immuno-active peptides Food Research International 2023-07-01 [PMID: 37254415] (ELISA, Human) Details: 1:5000 ELISA dilution	ELISA	Human
Alakhras NS, Shin J, Smith SA et al. Peanut allergen inhibition prevents anaphylaxis in a humanized mouse model Science translational medicine 2023-02-08 [PMID: 36753563]
Vukovic N, Halabi S, Russo-Cabrera JS et al. A human IgE bispecific antibody shows potent cytotoxic capacity mediated by monocytes The Journal of biological chemistry Jun 16 2022 [PMID: 35718062]
Premrov Bajuk B, Zrimsek P, Kotnik T Et Al. Insect Protein-Based Diet as Potential Risk of Allergy in Dogs Animals : an open access journal from MDPI Jun 29 2021 [PMID: 34209808] (WB)	WB

Array NBP3-11412

• IgE Antibodies
• IgE ELISA Kits
• IgE Isotype Controls
• IgE Antibody