Fc epsilon RI Antibody (AER-37) [Biotin] Summary
Immunogen |
The immunogen for this antibody was FceRI alpha. |
Isotype |
IgG2b Kappa |
Clonality |
Monoclonal |
Host |
Mouse |
Gene |
FCER1A |
Purity |
Protein A or G purified |
Innovator's Reward |
Test in a species/application not listed above to receive a full credit towards a future purchase. |
Applications/Dilutions
Dilutions |
- Flow Cytometry 1:10-1:1000
|
Application Notes |
The AER-37 antibody has been tested by flow cytometric analysis of peripheral blood leukocytes. This can be used at less than or equal to 1 ug per test. Cell number should be determined empirically but can range from 10^5to 10^8cells/test. |
Readout System |
|
Reactivity Notes
Use in Human reported in scientific literature (PMID:33741501).
Packaging, Storage & Formulations
Storage |
Store at 4C. Do not freeze. |
Buffer |
PBS (pH 7.2) with 0.1% gelatin |
Preservative |
0.09% Sodium Azide |
Concentration |
5 mg/ml |
Purity |
Protein A or G purified |
Alternate Names for Fc epsilon RI Antibody (AER-37) [Biotin]
Background
The AER-37 monoclonal antibody reacts with the Fc epsilon RI alpha subunit, an IgE-binding subunit lacking signal-transducing ability. Fc epsilon RI alpha is expressed on mast and basophil cells and is upregulated by the presence of IgE. Fc epsilon RI alpha forms a tetrameric complex with one beta and two gamma subunits. The beta and gamma subunits possess immunoreceptor tyrosine-based activation motifs (ITAM). The Fc epsilon RI complex plays an important role in triggering IgE-mediated allergic reactions.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are
guaranteed for 1 year from date of receipt.
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FAQs for Fc epsilon RI Antibody (NBP1-43522) (0)
Secondary Antibodies
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