Fatty Acid Synthase/FASN Antibody [Unconjugated]

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

FASN (Fatty Acid SyNthase; also FAS) is a cytosolic member of the short chain dehydrogenase/reductase family 27X. It is expressed in neurons, skeletal muscle, adipocytes and hepatocytes and both catalyzes the formation of palmitic acid from acetylCoA and malonylCoA and likely mediates the transfer of fatty acids to peptides. Human FASN is 2511 amino acids (aa) in length. It contains multiple domains, including a beta ‑ketoacyl synthase domain (aa 1‑414), an acyl and malonyl transferase domain (aa 429‑817), an enoyl reductase domain (aa 1563‑1863), a beta ‑ketoacyl reductase domain (aa 1864‑2118) and a thioesterase domain (aa 2207‑2511). FASN exists as an antiparallel homodimer. There is one theoretical alternative start site at Met2073. Over aa 10‑212, human FASN shares 92% aa identity with mouse FASN.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publication using AF5927	Applications	Species
Xiang J, Deng YY, Liu HX, Pu Y LncRNA MALAT1 Promotes PPAR alpha/CD36-Mediated Hepatic Lipogenesis in Nonalcoholic Fatty Liver Disease by Modulating miR-206/ARNT Axis Frontiers in bioengineering and biotechnology 6/13/2022 [PMID: 35769097]

Array AF5927

• Fatty Acid Synthase/FASN Antibodies
• Fatty Acid Synthase/FASN ELISA Kits
• Fatty Acid Synthase/FASN Lysate
• Fatty Acid Synthase/FASN Proteins