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EGR2 Antibody (27C3)

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Western Blot: EGR2 Antibody (27C3) [NBP3-26605] - Positive Western Blot detected in: SY5Y whole cell lysate, U251 whole cell lysate, MCF7 whole cell lysate, K562 whole cell lysate, Mouse Brain tissue lysate, Mouse Brain tissue lysate. All lanes: EGR2 Antibody at 1: 1000 Secondary: Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 50 kDa Observed band size: 50 kDa
Western Blot: EGR2 Antibody (27C3) [NBP3-26605] - Positive Western Blot detected in: SY5Y whole cell lysate, U251 whole cell lysate, MCF7 whole cell lysate, K562 whole cell lysate, Mouse Brain tissue lysate, Mouse Brain ...read more
Flow Cytometry: EGR2 Antibody (27C3) [NBP3-26605] - Overlay Peak curve showing SH-SY5Y cells stained with EGR2 Antibody (27C3) (red line) at 1:50. The cells were fixed in 4% formaldehyde and permeated by 0.2% Triton ...read more

Product Details

Summary
Reactivity Hu, MuSpecies Glossary
Applications WB, ELISA, Flow
Clone
27C3
Clonality
Monoclonal
Host
Rabbit
Conjugate
Unconjugated

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EGR2 Antibody (27C3) Summary

Additional Information
Recombinant monoclonal antibody expressed in HEK293F cells
Immunogen
A synthesized peptide derived from Human EGR2 [UniProt P11161]
Isotype
IgG
Clonality
Monoclonal
Host
Rabbit
Gene
EGR2
Purity
Affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
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Applications/Dilutions

Dilutions
  • ELISA
  • Flow Cytometry 1:50-1:200
  • Western Blot 1:500-1:2000

Packaging, Storage & Formulations

Storage
Store at -20 to -70C. Avoid freeze-thaw cycles.
Buffer
PBS, pH 7.4, 150mM NaCl and 50% glycerol
Preservative
0.02% Sodium Azide
Purity
Affinity purified

Alternate Names for EGR2 Antibody (27C3)

  • AT591
  • CMT1D
  • CMT4E
  • early growth response 2 (Krox-20 homolog, Drosophila)
  • early growth response 2
  • early growth response protein 2
  • EGR-2
  • FLJ14547
  • Krox-20 homolog, Drosophila
  • KROX-20, Drosophila, homolog (early growth response-2)
  • KROX20DKFZp686J1957
  • Zinc finger protein Krox-20

Background

Early Growth Response 2 (EGR2) is an early growth response family member which binds to specific areas of DNA and helps control the activity of particular genes. Specifically, EGR2 activates several genes that are involved in the formation and maintenance of myelin, the fatty substance that covers and protects nerve cells.

Defects in EGR2 have been linked to a number of diseases including congenital hypomyelination neuropathy, Charcot-Marie-Tooth disease type 1D, and Dejerine-Sottas neuropathy. EGR 2 antibodies may be useful tools for nerurscience research.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol EGR2