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Dopamine beta-Hydroxylase Antibody (DBH/7224) [Janelia Fluor® 549]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications IHC
Clone
DBH/7224
Clonality
Monoclonal
Host
Mouse
Conjugate
Janelia Fluor 549

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Dopamine beta-Hydroxylase Antibody (DBH/7224) [Janelia Fluor® 549] Summary

Immunogen
Recombinant fragment (around aa200-400) of human Dopamine beta-Hydroxylase protein (exact sequence is proprietary)
Localization
Cytoplasm
Isotype
IgG2 Kappa
Clonality
Monoclonal
Host
Mouse
Gene
DBH
Purity
Protein A or G purified
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Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry-Paraffin
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified

Notes



Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for Dopamine beta-Hydroxylase Antibody (DBH/7224) [Janelia Fluor® 549]

  • DBH
  • DBM
  • dopamine beta-hydroxylase (dopamine beta-monooxygenase)
  • Dopamine betaHydroxylase
  • Dopamine beta-Hydroxylase
  • Dopamine beta-monooxygenase
  • DOPBHY
  • EC 1.14.17.1

Background

Dopamine beta-hydroxylase belongs to the copper type II, ascorbate-dependent monooxygenase family and catalyzes the oxidative hydroxylation of dopamine to noradrenaline. It is almost exclusively located in the adrenal medulla and the synaptic vesicles of postganglionic sympathetic neurons being expressed in noradrenergic and adrenergic neurons. DBH serves as a marker of noradrenergic cells.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol DBH