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Dectin-1/CLEC7A Antibody - BSA Free

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Western Blot: Dectin-1/CLEC7A Antibody [NBP2-41170] - Western blot analysis of CLEC7A in rat spleen tissue lysate with CLEC7A antibody at (A) 1 and (B) 2 ug/mL.
Immunocytochemistry/ Immunofluorescence: Dectin-1/CLEC7A Antibody [NBP2-41170] - Immunofluorescence of CLEC7A in human spleen tissue withCLEC7A antibody at 20 ug/mL.
Immunohistochemistry-Paraffin: Dectin-1/CLEC7A Antibody [NBP2-41170] - Human spleen tissue with CLEC7A antibody at 5 ug/mL.
Immunohistochemistry: Dectin-1/CLEC7A Antibody - BSA Free [NBP2-41170] - Immunohistochemistry of Dectin-1/CLEC7A in human spleen tissue with Dectin-1/CLEC7A antibody at 5 u/mL.
Immunocytochemistry/ Immunofluorescence: Dectin-1/CLEC7A Antibody - BSA Free [NBP2-41170] - Immunofluorescence of Dectin-1/CLEC7A in Jurkat cells with Dectin-1/CLEC7A antibody at 20 u/mL.
Immunocytochemistry/ Immunofluorescence: Dectin-1/CLEC7A Antibody - BSA Free [NBP2-41170] - Immunofluorescence of Dectin-1/CLEC7A in Jurkat cells with Dectin-1/CLEC7A antibody at 20 u/mL.
Immunohistochemistry: Dectin-1/CLEC7A Antibody - BSA Free [NBP2-41170] - Immunohistochemistry of Dectin-1/CLEC7A in human spleen tissue with Dectin-1/CLEC7A antibody at 5 u/mL.

Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB, ELISA, ICC/IF, IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Format
BSA Free
Concentration
1 mg/ml

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Dectin-1/CLEC7A Antibody - BSA Free Summary

Immunogen
Antibody was raised against a 17 amino acid synthetic peptide near the center of human CLEC7A. The immunogen is located within amino acids 70 - 120 of CLEC7A. Amino Acid Squence: LSRNKENHSQPTQSSLE
Specificity
Multiple isoforms of CLEC7A are known to exist.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
CLEC7A
Purity
Peptide affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • ELISA
  • Immunocytochemistry/ Immunofluorescence 20 ug/ml
  • Immunohistochemistry 5 ug/mL
  • Immunohistochemistry-Paraffin 5 ug/mL
  • Western Blot 1 - 2 ug/mL
Theoretical MW
27 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Bovine (88%)

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.02% Sodium Azide
Concentration
1 mg/ml
Purity
Peptide affinity purified

Alternate Names for Dectin-1/CLEC7A Antibody - BSA Free

  • Beta-glucan receptor
  • BGR
  • CD369
  • CLEC7A
  • CLECSF12
  • CLECSF12DC-associated C-type lectin 1
  • C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamilymember 12
  • C-type lectin domain family 7 member A
  • C-type lectin domain family 7, member A
  • C-type lectin superfamily member 12
  • Dectin1
  • Dectin-1
  • DECTIN1CANDF4
  • Dendritic cell-associated C-type lectin 1
  • dendritic cell-associated C-type lectin-1
  • hDectin-1
  • lectin-like receptor 1

Background

Dectin1 encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. The encoded glycoprotein is a small type II membrane receptor with an extracellular C-type lectin-like domain fold and a cytoplasmic domain with an immunoreceptor tyrosine-based activation motif. It functions as a pattern-recognition receptor that recognizes a variety of beta-1,3-linked and beta-1,6-linked glucans from fungi and plants, and in this way plays a role in innate immune response. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. This gene is closely linked to other CTL/CTLD superfamily members on chromosome 12p13 in the natural killer gene complex region.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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WB Video Protocol
ICC/IF Video Protocol

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Bioinformatics

Gene Symbol CLEC7A