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DAP10/HCST Antibody (982107) [Unconjugated]

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Immunohistochemistry-Paraffin: DAP10/HCST Antibody (982107) [Unconjugated] [MAB97862] - DAP10/HCST was detected in immersion fixed paraffin-embedded sections of human kidney using Mouse Anti-Human DAP10/HCST Monoclonal ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow, IHC
Clone
982107
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated
Concentration
1.0 mg/ml

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DAP10/HCST Antibody (982107) [Unconjugated] Summary

Immunogen
Synthetic peptide containing human DAP10/HCST
Isotype
IgG2a
Clonality
Monoclonal
Host
Mouse
Gene
HCST
Purity
Protein A or G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Flow Cytometry 1:10 - 1:1000
  • Immunohistochemistry 5 ug/ml
  • Immunohistochemistry-Paraffin 5 ug/ml

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.02% Sodium Azide
Concentration
1.0 mg/ml
Purity
Protein A or G purified

Alternate Names for DAP10/HCST Antibody (982107) [Unconjugated]

  • DAP10
  • DAP10PIK3AP
  • DKFZP586C1522
  • HCST
  • hematopoietic cell signal transducer
  • KAP10
  • KAP10DNAX-activation protein 10
  • kinase assoc pro of ~10kDa
  • Kinase Assoc Protein
  • Membrane protein DAP10
  • phosphoinositide-3-kinase adaptor protein
  • PIK3AP
  • Transmembrane adapter protein KAP10

Background

HCST encodes a transmembrane signaling adaptor that contains a YxxM motif in its cytoplasmic domain. The encoded protein may form part of the immune recognition receptor complex with the C-type lectin-like receptor NKG2D. As part of this receptor complex, this protein may activate phosphatidylinositol 3-kinase dependent signaling pathways through its intracytoplasmic YxxM motif. This receptor complex may have a role in cell survival and proliferation by activation of NK and T cell responses. Alternative splicing results in two transcript variants encoding different isoforms.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol HCST