CD94 Antibody (131412) [Unconjugated]

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

The type-II transmembrane glycoprotein CD94 covalently associates with C-type lectins of the NKG2 family to yield heterodimers important in NK cell recognition of class I MHC molecules. CD94/NKG2A complexes are also found on a subset of CD8+ T cells. Expression of CD94/NKG2 heterodimers may regulate cell survival and effector functions. There are two alternatively spliced variants of CD94 that differ by 31 amino acids encoded by exon 2.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 1 confirmed species: Human.

We have publications tested in 3 applications: Flow Cytometry, Functional Assay, Neutralization.

Showing Publications 1 - 4 of 4.

Publications using MAB1058	Applications	Species
Q Hammer, J Dunst, W Christ, F Picarazzi, M Wendorff, P Momayyezi, O Huhn, HK Netskar, KT Maleki, M García, T Sekine, E Sohlberg, V Azzimato, M Aouadi, Karolinska, Severe COV, F Degenhardt, A Franke, F Spallotta, M Mori, J Michaëlsso, NK Björkström, T Rückert, C Romagnani, A Horowitz, J Klingström, HG Ljunggren, KJ Malmberg SARS-CoV-2 Nsp13 encodes for an HLA-E-stabilizing peptide that abrogates inhibition of NKG2A-expressing NK cells Cell Reports, 2022-02-21;0(0):110503. 2022-02-21 [PMID: 35235832] (Neutralization, Human)	Neutralization	Human
Nachmani D, Zimmermann A, Oiknine Djian E, Weisblum Y, Livneh Y, Khanh Le V, Galun E, Horejsi V, Isakov O, Shomron N, Wolf D, Hengel H, Mandelboim O MicroRNA editing facilitates immune elimination of HCMV infected cells. PLoS Pathog, 2014-02-27;10(2):e1003963. 2014-02-27 [PMID: 24586166] (Flow Cytometry, Human)	Flow Cytometry	Human
Angelini DF, Zambello R, Galandrini R, Diamantini A, Placido R, Micucci F, Poccia F, Semenzato G, Borsellino G, Santoni A, Battistini L NKG2A inhibits NKG2C effector functions of gammadelta T cells: implications in health and disease. J. Leukoc. Biol., 2010-10-15;89(1):75-84. 2010-10-15 [PMID: 20952657] (Functional Assay, Human)	Functional Assay	Human
Yu J, Mao HC, Wei M, Hughes T, Zhang J, Park IK, Liu S, McClory S, Marcucci G, Trotta R, Caligiuri MA CD94 surface density identifies a functional intermediary between the CD56bright and CD56dim human NK-cell subsets. Blood, 2009-11-06;115(2):274-81. 2009-11-06 [PMID: 19897577] (Flow Cytometry, Human)	Flow Cytometry	Human

Array MAB1058

• CD94 Antibodies
• CD94 ELISA Kit
• CD94 Lysates
• CD94 Protein
• CD94 Proteins and Enzymes