CXCR5 Antibody (614641) [Unconjugated]

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

CXCR5 (CXC chemokine receptor 5; also BLR-1, NLR and CD185) is a 55-60 kDa member of the G-protein coupled receptor 1 family. It is expressed on select cell types, including granule and Purkinje cell neurons, embryonic CD4+ CD3- IL-7R alpha + precursor cells, B cells and follicular T helper cells. CXCR5 selectively binds BLC/CXCL13. This appears to both promote embryonic lymph node development and, in the adult, direct expressing cells to positions that optimize antigen presentation and antibody production. Mouse CXCR5 is a 7-transmembrane glycoprotein that is 374 amino acids (aa) in length. It contains a 57 aa N-terminal extracellular region plus a 47 aa C-terminal cytoplasmic domain. Over aa 1-57, mouse CXCR5 shares 84% and 47% aa identity with rat and human CXCR5, respectively.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 1 confirmed species: Mouse.

We have publications tested in 1 application: IHC.

Showing Publication 1 - 1 of 1.

Publication using MAB6198	Applications	Species
Malyshkina, A;Bayer, W;Podschwadt, P;Otto, L;Karakoese, Z;Sutter, K;Bruderek, K;Wang, B;Lavender, KJ;Santiago, ML;Leipe, PM;Elsner, C;Esser, S;Brandau, S;Gunzer, M;Dittmer, U; Immunotherapy-induced cytotoxic T follicular helper cells reduce numbers of retrovirus-infected reservoir cells in B cell follicles PLoS pathogens 2023-10-01 [PMID: 37883584] (IHC, Mouse)	IHC	Mouse

Array MAB6198

• CXCR5 Antibodies
• CXCR5 ELISA Kits
• CXCR5 Lysate
• CXCR5 Protein