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CXCR2/IL-8RB Antibody (48311) [Fluorescein]

 (9 Publications)
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Human peripheral blood granulocytes were stained with Mouse Anti-Human CXCR2/IL-8 RB Fluorescein-conjugated Monoclonal Antibody (Catalog # FAB331F, filled histogram) or isotype control antibody (Catalog # IC003F, open histogram). View our protocol for Staining Membrane-associated Proteins.
Human peripheral blood granulocytes were stained with Mouse Anti-Human CXCR2/IL-8 RB Fluorescein-conjugated Monoclonal Antibody (Catalog # FAB331F, filled histogram) or isotype control antibody (Catalog # IC003F, open ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow
Clone
48311
Clonality
Monoclonal
Host
Mouse
Conjugate
Fluorescein

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
FAB331U-100UG
Alexa Fluor 405
FAB331V-100UG
Alexa Fluor 488
FAB331G-100UG
Alexa Fluor 532
FAB331X
Alexa Fluor 594
FAB331T-100UG
Alexa Fluor 647
FAB331R-100UG
Alexa Fluor 700
FAB331N-100UG
Alexa Fluor 750
FAB331S-100UG
Allophycocyanin
FAB331A-025
Allophycocyanin
FAB331A-100
Allophycocyanin/Cy7
FAB331APCCY7
Biotin
FAB331B
DyLight 350
FAB331D
DyLight 405
FAB331E
DyLight 488
FAB331K
DyLight 550
FAB331L
DyLight 594
FAB331M
DyLight 650
FAB331W
DyLight 680
FAB331Y
DyLight 755
FAB331Z
Fluorescein
FAB331F-100
HRP
FAB331H
Janelia Fluor 549
FAB331I
Janelia Fluor 646
FAB331J
PE/Atto594
FAB331PEATT594
PE/Cy5.5
FAB331PECY55
PE/Cy7
FAB331PECY7
Phycoerythrin
FAB331P-100
Phycoerythrin
FAB331P-025
Unconjugated
MAB331-100
mFluor Violet 450 SE
FAB331MFV450
mFluor Violet 500 SE
FAB331MFV500
mFluor Violet 610 SE
FAB331MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
MAB331-100
Carrier Free
FAB331V-100UG
Carrier Free
MAB331-500
Carrier Free
FAB331G-100UG
Carrier Free
FAB331R-100UG
Carrier Free
FAB331S-100UG
Carrier Free
FAB331T-100UG
Carrier Free
FAB331U-100UG
Carrier Free
MAB331-SP
Carrier Free
FAB331A-100
Carrier Free
FAB331A-025
Carrier Free
MAB331-100
Carrier Free
FAB331P-100
Carrier Free
FAB331P-025
Carrier Free
FAB331F-100
Carrier Free
FAB331N-100UG
100% Guarantee on every product

CXCR2/IL-8RB Antibody (48311) [Fluorescein] Summary

Additional Information
Clone 48311 was used by HLDA to establish CD designation
Immunogen
NS0 mouse myeloma cell line transfected with human CXCR2/IL-8 RB
Met1-Leu355
Accession # AAB25880
Specificity
Detects human CXCR2/IL-8 RB transfected NS0 cells but not the parental cell line. It does not cross-react with CXCR1 (IL-8 RA).
Source
N/A
Isotype
IgG2a
Clonality
Monoclonal
Host
Mouse
Gene
CXCR2
Purity Statement
Protein A or G purified from ascites
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
Learn about the Innovator's Reward

Applications/Dilutions

Dilutions
  • Flow Cytometry 10 uL/10^6 cells
Publications
Read Publications using
FAB331F in the following applications:

Packaging, Storage & Formulations

Storage
Protect from light. Do not freeze.
  • 12 months from date of receipt, 2 to 8 °C as supplied.
Buffer
Supplied in a saline solution containing BSA and Sodium Azide.
Preservative
Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for CXCR2/IL-8RB Antibody (48311) [Fluorescein]

  • CD182 antigen
  • CD182
  • CDw128b
  • chemokine (C-X-C motif) receptor 2
  • chemokine (CXC) receptor 2
  • CMKAR2
  • C-X-C chemokine receptor type 2
  • CXCR2 gene for IL8 receptor type B
  • CXCR2
  • CXC-R2
  • CXCR-2
  • GRO/MGSA receptor
  • High affinity interleukin-8 receptor B
  • IL-8 RB
  • IL-8 receptor type 2
  • IL-8R B
  • IL8R2
  • IL8RA
  • IL8RB
  • interleukin 8 receptor B
  • interleukin 8 receptor type 2
  • interleukin-8 receptor type B

Background

CXCR2, also known as IL-8 RB, is a G protein-coupled chemokine receptor expressed on neutrophils. It binds IL-8, GRO alpha , GRO beta , GRO gamma , NAP-2, and ENA-78.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for CXCR2/IL-8RB Antibody (FAB331F)(9)

We have publications tested in 2 confirmed species: Human, Mouse.

We have publications tested in 2 applications: Flow Cytometry, ICC.


Filter By Application
Flow Cytometry
(6)
ICC
(1)
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Human
(6)
Mouse
(1)
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Showing Publications 1 - 9 of 9.
Publications using FAB331F Applications Species
Rosa Mistica C. Ignacio, Yuan-Lin Dong, Syeda M. Kabir, Hyeongjwa Choi, Eun-Sook Lee, Andrew J. Wilson et al. CXCR2 is a negative regulator of p21 in p53-dependent and independent manner via Akt-mediated Mdm2 in ovarian cancer Oncotarget 2018-02-09 [PMID: 29515768]
Hazeldine J, Harris P, Chapple I, Grant M, Greenwood H, Livesey A, Sapey E, Lord J Impaired neutrophil extracellular trap formation: a novel defect in the innate immune system of aged individuals. Aging Cell, 2014-04-30;13(4):690-8. 2014-04-30 [PMID: 24779584] (Flow Cytometry, Human) Flow Cytometry Human
Morandi , Fabio, Di Carlo , Emma, Ferrone , Soldano, Petretto , Andrea, Pistoia , Vito, Airoldi , Irma IL-27 in human secondary lymphoid organs attracts myeloid dendritic cells and impairs HLA class I-restricted antigen presentation. J Immunol, 2014-02-19;192(6):2634-42. 2014-02-19 [PMID: 24554774] (Flow Cytometry, Human) Flow Cytometry Human
Liu L, Xie F, Chang K, Li M, Meng Y, Wang X, Li H, Li D, Yu J Hypoxia promotes the proliferation of cervical carcinoma cells through stimulating the secretion of IL-8. Int J Clin Exp Pathol, 2014-01-15;7(2):575-83. 2014-01-15 [PMID: 24551277] (Flow Cytometry, Human) Flow Cytometry Human
Eikawa S, Ohue Y, Kitaoka K Enrichment of Foxp3+ CD4 regulatory T cells in migrated T cells to IL-6- and IL-8-expressing tumors through predominant induction of CXCR1 by IL-6. J. Immunol., 2010-11-03;185(11):6734-40. 2010-11-03 [PMID: 21048114] (Flow Cytometry, Human) Flow Cytometry Human
Yang G, Rosen DG, Liu G CXCR2 promotes ovarian cancer growth through dysregulated cell cycle, diminished apoptosis, and enhanced angiogenesis. Clin. Cancer Res., 2010-05-26;16(15):3875-86. 2010-05-26 [PMID: 20505188] (ICC, Human) ICC Human
Maxwell PJ, Gallagher R, Seaton A, Wilson C, Scullin P, Pettigrew J, Stratford IJ, Williams KJ, Johnston PG, Waugh DJ HIF-1 and NF-kappaB-mediated upregulation of CXCR1 and CXCR2 expression promotes cell survival in hypoxic prostate cancer cells. Oncogene, 2007-05-28;26(52):7333-45. 2007-05-28 [PMID: 17533374] (Flow Cytometry, Human) Flow Cytometry Human
Mihara K, Smit MJ, Krajnc-Franken M, Gossen J, Rooseboom M, Dokter W Human CXCR2 (hCXCR2) takes over functionalities of its murine homolog in hCXCR2 knockin mice. Eur. J. Immunol., 2005-09-01;35(9):2573-82. 2005-09-01 [PMID: 16094689] (Flow Cytometry, Mouse) Flow Cytometry Mouse
Björn Frendéus, Gabriela Godaly, Long Hang, Diana Karpman, Ann-Charlotte Lundstedt, Catharina Svanborg Interleukin 8 Receptor Deficiency Confers Susceptibility to Acute Experimental Pyelonephritis and May Have a Human Counterpart J. Exp. Med 2000-09-18 [PMID: 10993918]

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Bioinformatics

Gene Symbol CXCR2
Uniprot