CTGF/CCN2 was detected in immersion fixed paraffin-embedded sections of human breast cancer tissue using 25 µg/mL Human CTGF/CCN2 C-Terminus Monoclonal Antibody (Catalog # MAB660) overnight at 4 °C. Tissue was ...read more
Immunostaining of neuroendocrine tumors. Representative photomicrographs demonstrating anti-connective tissue growth factor (CCN2) (panel A) immunostaining of gut carcinoid tumor tissue. CCN2 immunoreactivity was seen ...read more
E. coli-derived recombinant human CTGF Glu247-Ala349 Accession # NP_001892.1
Specificity
Detects human CTGF C-teriminal peptide in direct ELISAs. Does not cross-react with recombinant human (rh) LDGF, rhNOV, rhPDGF, rhPlGF, rhVEGF206, rhVEGF-B186, rhVEGF-C, rhVEGF-D, or rhWISP-1.
Source
N/A
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
CTGF
Purity Statement
Protein A or G purified from ascites
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70 °C as supplied.
1 month, 2 to 8 °C under sterile conditions after reconstitution.
6 months, -20 to -70 °C under sterile conditions after reconstitution.
Buffer
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Preservative
No Preservative
Reconstitution Instructions
Reconstitute at 0.5 mg/mL in sterile PBS.
Notes
This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.
Alternate Names for CTGF/CCN2 Antibody (88430) - C-terminus
CCN2
CCN2IGFBP-8
connective tissue growth factor
CTGF
CTGRP
Fisp12
HCS24
Hypertrophic chondrocyte-specific protein 24
IBP-8
IGF-binding protein 8
IGFBP-8
IGFBP8CCN family member 2
Insulin-like growth factor-binding protein 8
MGC102839
NOV2
Background
CTGF belongs to the CCN (CYR61/CTGF/NOV) family of secreted proteins
that share a common multimodular organization. Each protein contains
IGF-binding protein domain, a von Willebrand factor type C domain, a
thrombospondin type I domain, and a cysteine knot domain. The
multimodular CTGF has the ability to bind multiple ligands and has
numerous effects on development, differentation, and disease. The
C-terminal cysteine knot motif contains the heparin and low density
lipoprotein receptor (LDLR) binding sites that contributes to the
adhesive and mitogenic properties of CTGF.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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FAQs for CTGF/CCN2 Antibody (MAB660). (Showing 1 - 1 of 1 FAQs).
We are looking for a pair of mouse CTGF antibody for ELISA, we prefer no azide and/or glycerol, and in carrier free form (no EDTA, no Tris, no BSA). For the validation, we need approximately 100ug. If it works, we'll order more later.
Unfortunately we do not carry any CTGF antibodies that suit your specifications. We do carry AbSelect antibody purification kits that will remove BSA, Tris and azide from antibody formulations which may be an option for you.
The concentration calculator allows you to quickly calculate the volume, mass or concentration of your vial. Simply enter your mass, volume, or concentration values for your reagent and the calculator will determine the rest.
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