COL1A2 Antibody

COL1A2 is the pro-alpha2 chain of type I collagen whose triple helix comprises two alpha1 chains and one alpha2 chain. Type I is a fibril-forming collagen found in most connective tissues and is abundant in bone, cornea, dermis and tendon. Mutations in this gene are associated with osteogenesis imperfecta types I-IV, Ehlers-Danlos syndrome type VIIB, recessive Ehlers-Danlos syndrome Classical type, idiopathic osteoporosis, and atypical Marfan syndrome. Symptoms associated with mutations in this gene, however, tend to be less severe than mutations in the gene for the alpha1 chain of type I collagen (COL1A1) reflecting the different role of alpha2 chains in matrix integrity.This gene encodes the pro-alpha2 chain of type I collagen whose triple helix comprises two alpha1 chains and one alpha2 chain. Type I is a fibril-forming collagen found in most connective tissues and is abundant in bone, cornea, dermis and tendon. Mutations in this gene are associated with osteogenesis imperfecta types I-IV, Ehlers-Danlos syndrome type VIIB, recessive Ehlers-Danlos syndrome Classical type, idiopathic osteoporosis, and atypical Marfan syndrome. Symptoms associated with mutations in this gene, however, tend to be less severe than mutations in the gene for the alpha1 chain of type I collagen (COL1A1) reflecting the different role of alpha2 chains in matrix integrity. Three transcripts, resulting from the use of alternate polyadenylation signals, have been identified for this gene. [provided by R. Dalgleish]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 1 confirmed species: Mouse.

We have publications tested in 1 application: WB.

Showing Publications 1 - 2 of 2.

Publications using NBP1-57987	Applications	Species
Wang Q, Sundar I, Li D et al. E-cigarette-Induced Pulmonary Inflammation and Dysregulated Repair are Mediated by nAChR ?7 Receptor: Role of nAChR ?7 in ACE2 Covid-19 receptor regulation Research Square 2022-11-07 [PMID: 32702718]
Wang Q, Sundar IK, Li D et al. E-cigarette-induced pulmonary inflammation and dysregulated repair are mediated by nAChR alpha 7 receptor: role of nAChR alpha 7 in SARS-CoV-2 Covid-19 ACE2 receptor regulation Respir. Res. 2020-06-18 [PMID: 32552811] (WB, Mouse) Details: Citation using the Alexa Fluor 488 format of this antibody.	WB	Mouse

Array NBP1-57987

• COL1A2 Antibodies
• COL1A2 ELISA Kits
• COL1A2 Proteins