Collagen I Antibody

Collagen I is one of the most abundant extracellular matrix (ECM) proteins in mammals and is an important structural component in connective tissues, bones, teeth, skin, heart, and lungs (1, 2). Collagen I is commonly used for biomedical purposes including providing an ECM microenvironment for cell attachment, proliferation, and mesenchymal stem cell growth and differentiation to the osteogenic lineage (1, 3, 4). Furthermore, type I Collagen hydrogels are a promising scaffold for engineering tissues and tumors (4). Collagen type I can be extracted from numerous sources including mammals, most commonly bovine and porcine, fish, amphibians, and birds (1, 4). Structurally, Collagen I is a heterotrimer comprised of two alpha-1 chains and one alpha-2 chain that together forms a triple helix (1, 3, 5). Each alpha chain is primarily formed by glycine, proline, and hydroxyproline repeats with the alpha-1 chains having a theoretical molecular weight of 139 kDa and 129 kDa for the alpha-2 chain (3). The dimeric form of Collagen I has a theoretical molecular weight of ~270 kDa while the trimeric form is >400 kDa (3, 5).

A variety of disease pathologies have been associated with mutations in or disruptions in collagen type I. Osteogenesis imperfecta, also known as brittle bone disease, is caused by autosomal dominant mutations in Collagen type I encoding genes and characterized by fragile bones and skeletal deformities (6). Ehlers-Danlos syndromes (EDS) is another disorder that affects soft connective tissue and its various clinical subtypes are associated with different mutations in Collagen I (7).

Alternative names for Collagen I includes alpha-1 type I collagen, alpha1(I) procollagen, CAFYD, COL1A1, collagen alpha 1 chain type I, collagen alpha-1(I) chain, EDSARTH1, EDSC, OI1, OI2, OI3, OI4, pro-alpha-1 collagen type 1, type I proalpha 1, and type I procollagen alpha 1 chain.

References

1. Chowdhury, S. R., Mh Busra, M. F., Lokanathan, Y., Ng, M. H., Law, J. X., Cletus, U. C., & Binti Haji Idrus, R. (2018). Collagen Type I: A Versatile Biomaterial. Advances in experimental medicine and biology. https://doi.org/10.1007/978-981-13-0947-2_21

2. Kisling, A., Lust, R. M., & Katwa, L. C. (2019). What is the role of peptide fragments of collagen I and IV in health and disease?. Life sciences. https://doi.org/10.1016/j.lfs.2019.04.042

3. Kwon, D., Kang, G. S., Han, D. K., Park, K., Kim, J. H., & Lee, S. H. (2014). Establishment and characterization of human engineered cells stably expressing large extracellular matrix proteins. Archives of pharmacal research. https://doi.org/10.1007/s12272-013-0294-0

4. Antoine, E. E., Vlachos, P. P., & Rylander, M. N. (2014). Review of collagen I hydrogels for bioengineered tissue microenvironments: characterization of mechanics, structure, and transport. Tissue engineering. Part B, Reviews. https://doi.org/10.1089/ten.TEB.2014.0086

5. Leon-Lopez, A., Morales-Penaloza, A., Martinez-Juarez, V. M., Vargas-Torres, A., Zeugolis, D. I., & Aguirre-alvarez, G. (2019). Hydrolyzed Collagen-Sources and Applications. Molecules (Basel, Switzerland). https://doi.org/10.3390/molecules24224031

6. Marini, J. C., Forlino, A., Bachinger, H. P., Bishop, N. J., Byers, P. H., Paepe, A., Fassier, F., Fratzl-Zelman, N., Kozloff, K. M., Krakow, D., Montpetit, K., & Semler, O. (2017). Osteogenesis imperfecta. Nature reviews. Disease primers. https://doi.org/10.1038/nrdp.2017.52

7. Callewaert, B., Malfait, F., Loeys, B., & De Paepe, A. (2008). Ehlers-Danlos syndromes and Marfan syndrome. Best practice & research. Clinical rheumatology, 22(1), 165-189. https://doi.org/10.1016/j.berh.2007.12.005

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 8 confirmed species: Human, Mouse, Rat, Bacteria, Bovine, Chicken, Porcine, Rabbit.

We have publications tested in 16 applications: B/N, ELISA, Flow, ICC, ICC/IF, IF, IF/IHC, IHC, IHC-Fr, IHC-P, IHC-WhMt, IP, In Vivo, MiAr, PAGE, WB.

Showing Publications 1 - 10 of 322. Show All 322 Publications. Collapse Publications.

Publications using NB600-408	Applications	Species
Salome Guillaumin, Mehmet Gurdal, Dimitrios I. Zeugolis, Gustavo Caetano-Anolles Gums as Macromolecular Crowding Agents in Human Skin Fibroblast Cultures Life 2024-03-25 [PMID: 38672707]
Drakos S, Shankar T, Visker J et al. Adipocyte Enhancer Binding Protein 1 (AEBP1) Inhibition as a Potential Anti-Fibrotic Therapy in Heart Failure. Research Square 2023-10-17 (WB, Mouse)	WB	Mouse
Jack H. Wellmerling, Sara R. Dresler, Jeffrey A. Meridew, Kyoung M. Choi, Daniel J. Tschumperlin, Qi Tan RNA ‐sequencing reveals differential fibroblast responses to bleomycin and pneumonectomy Physiological Reports 2024-07-11 [PMID: 38991987]
Biswajoy Ghosh, Jyotirmoy Chatterjee, Ranjan Rashmi Paul, Sebastian Acuña, Pooja Lahiri, Mousumi Pal, Pabitra Mitra, Krishna Agarwal Molecular histopathology of matrix proteins through autofluorescence super-resolution microscopy Scientific Reports 2024-05-08 [PMID: 38719976]
Jan-Niklas May, Jennifer I Moss, Florian Mueller, Susanne K Golombek, Ilaria Biancacci, Larissa Rizzo, Asmaa Said Elshafei, Felix Gremse, Robert Pola, Michal Pechar, Tomáš Etrych, Svea Becker, Christian Trautwein, Roman D Bülow, Peter Boor, Ruth Knuechel, Saskia von Stillfried, Gert Storm, Sanyogitta Puri, Simon T Barry, Volkmar Schulz, Fabian Kiessling, Marianne B Ashford, Twan Lammers Histopathological biomarkers for predicting the tumour accumulation of nanomedicines. Nature biomedical engineering 2024-04-08 [PMID: 38589466]
Yiwei Wang, Xingchen Geng, Zhihua Guo, Dandan Chu, Ruixing Liu, Boyuan Cheng, Haohao Cui, Chengcheng Li, Jingguo Li, Zhanrong Li M2 macrophages promote subconjunctival fibrosis through YAP/TAZ signalling Annals of Medicine 2024-02-09 [PMID: 38335557]
Salli Talvi, Johanna Jokinen, Kalle Sipilä, Pekka Rappu, Fu-Ping Zhang, Matti Poutanen, Pia Rantakari, Jyrki Heino Embigin deficiency leads to delayed embryonic lung development and high neonatal mortality in mice. iScience 2024-02-16 [PMID: 38318368]
Drakos S, Shankar T, Visker J et al. Adipocyte Enhancer Binding Protein 1 (AEBP1) Inhibition as a Potential Anti-Fibrotic Therapy in Heart Failure. Research Square 2023-10-17 (IHC, Mouse)	IHC	Mouse
Rajadurai A, Tsao H Identification of collagen-suppressive agents in keloidal fibroblasts using a high-content, phenotype-based drug screen JID Innovations 2023-11-01 [PMID: 38303762] (WB)	WB
Yang Q, Huo E, Cai Y et al. Myeloid PFKFB3-mediated glycolysis promotes kidney fibrosis Frontiers in immunology 2023-11-16 [PMID: 38035106] (WB, Mouse)	WB	Mouse
Zhang K, Zhang MX, Meng XX et al. Targeting GPR65 alleviates hepatic inflammation and fibrosis by suppressing the JNK and NF-?B pathways Military Medical Research 2023-11-25 [PMID: 38001521] (WB, IHC, Mouse, Human)	WB, IHC	Mouse, Human
Liu S, Li B, Liu N et al. Multi-omics analysis of human tendon adhesion reveals ACKR1 migrates macrophages involve in endogenous regeneration Research Square 2023-10-30 (IHC, Human)	IHC	Human
Camarena, V;Williams, MM;Morales, AA;Zafeer, MF;Kilic, OV;Kamiar, A;Abad, C;Rasmussen, MA;Briski, LM;Peart, L;Bademci, G;Barbouth, DS;Smithson, S;Wang, G;Shehadeh, LA;Walz, K;Tekin, M; ADAMTSL2 mutations determine the phenotypic severity in Geleophysic Dysplasia JCI insight 2024-02-01 [PMID: 38300707]
Yoon-Young Kang, Dong-Young Kim, Sang-Yong Lee, Hee-Joong Kim, Taehawn Kim, Jeong A Cho, Taewon Lee, Eun Young Choi Innate Immune Training Initiates Efferocytosis to Protect against Lung Injury. Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024-01-26 [PMID: 38279580]
Laura Jahnke, Virginie Perrenoud, Souska Zandi, Yuebing Li, Federica Maria Conedera, Volker Enzmann, Girish Kumar Srivastava Modulation of Extracellular Matrix Composition and Chronic Inflammation with Pirfenidone Promotes Scar Reduction in Retinal Wound Repair Cells 2024-01-16 [PMID: 38247855]
Junichi Saito, Jui M. Dave, Freddy Duarte Lau, Daniel M. Greif Presenilin-1 in smooth muscle cells facilitates hypermuscularization in elastin aortopathy iScience 2023-12-13 [PMID: 38226162]
Amy Lewis, David T Humphreys, Belen Pan-Castillo, Giulio Berti, Carla Felice, Hannah Gordon, Radha Gadhok, Anke Nijhuis, Shameer Mehta S, Liliane Eleid, Sidra Iqbal, Alessandro Armuzzi, Annamaria Minicozzi, Eleni Giannoulatou, Joanne ChinAleong, Roger Feakins, Virag Sagi-Kiss, Dora Barisic, Margarita-Ioanna Koufaki, Jacob G Bundy, James O Lindsay, Andrew Silver Epigenetic and Metabolic Reprogramming of Fibroblasts in Crohn’s Disease Strictures Reveals Histone Deacetylases as Therapeutic Targets Journal of Crohn's & Colitis 2024-06-01 [PMID: 38069679]
Scaria SM, Frumm SM, Vikram EP et al. Epimorphic regeneration in the mammalian tympanic membrane NPJ Regenerative medicine 2023-10-18 [PMID: 37852984] (IHC-WhMt, Mouse)	IHC-WhMt	Mouse
Lee KW, Chung K, Nam DH et al. Decellularized allogeneic cartilage paste with human costal cartilage and crosslinked hyaluronic acid-carboxymethyl cellulose carrier augments microfracture for improved articular cartilage repair Acta biomaterialia 2023-10-07 [PMID: 37813156] (IHC, Rabbit)	IHC	Rabbit
Choi S, Ham S, Lee YI et al. Silibinin Downregulates Types I and III Collagen Expression via Suppression of the mTOR Signaling Pathway Int J Mol Sci 2023-09-21 [PMID: 37762688] (B/N)	B/N
Ballester-Servera C, Alonso J, Cañes L et al. Lysyl oxidase-dependent extracellular matrix crosslinking modulates calcification in atherosclerosis and aortic valve disease Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023-09-18 [PMID: 37729730]
Chinnapaka S, Yang KS, Surucu Y et al. Human adipose ECM alleviates radiation-induced skin fibrosis via endothelial cell-mediated M2 macrophage polarization iScience 2023-09-15 [PMID: 37705953]
Yang Q, Huo E, Cai Y et al. PFKFB3-Mediated Glycolysis Boosts Fibroblast Activation and Subsequent Kidney Fibrosis Cells 2023-08-17 [PMID: 37626891] (B/N, WB)	B/N, WB
Liu C, Zhou D, Zhang Q et al. Transcription factor EB (TFEB) improves ventricular remodeling after myocardial infarction by inhibiting Wnt/?-catenin signaling pathway PeerJ 2023-08-18 [PMID: 37609444] (B/N, WB)	B/N, WB
Fang, L;Zhou, L;Kulić, Ž;Lehner, MD;Tamm, M;Roth, M; EPs® 7630 Stimulates Tissue Repair Mechanisms and Modifies Tight Junction Protein Expression in Human Airway Epithelial Cells International journal of molecular sciences 2023-07-07 [PMID: 37446408] (WB)	WB
Hernández-Bule ML, Toledano-Macías E, Pérez-González LA et al. Anti-Fibrotic Effects of RF Electric Currents International journal of molecular sciences 2023-07-01 [PMID: 37446165] (ICC/IF)	ICC/IF
Gobbo F, Zingariello M, Verachi P et al. GATA1-defective immune-megakaryocytes as possible drivers of idiopathic pulmonary fibrosis bioRxiv 2023-09-19 [PMID: 37425686] (IHC, ICC/IF)	IHC, ICC/IF
Gäberlein K, Schröder SK, Nanda I et al. Genetic Characterization of Rat Hepatic Stellate Cell Line PAV-1 Cells 2023-06-11 [PMID: 37371073] (WB, Rat)	WB	Rat
Zhu X, Wang Y, Soaita I et al. Acetate controls endothelial-to-mesenchymal transition Cell metabolism 2023-06-08 [PMID: 37327791] (WB, Human)	WB	Human
Zhao T, Chu Z, Chu C et al. Macrophages induce gingival destruction via Piezo1-mediated MMPs-degrading collagens in periodontitis Frontiers in Immunology 2023-05-16 [PMID: 37261355] (ICC/IF, Human, Mouse) Details: Dilution: 1:100	ICC/IF	Human, Mouse
Hwang AR, Lee HJ, Kim S et al. Inhibition of p90RSK Ameliorates PDGF-BB-Mediated Phenotypic Change of Vascular Smooth Muscle Cell and Subsequent Hyperplasia of Neointima International Journal of Molecular Sciences 2023-04-30 [PMID: 37175802] (In Vivo, B/N)	In Vivo, B/N
Silva CS, Pinto RD, Pires RA et al. The Influence of Feeder Cell-Derived Extracellular Matrix Density on Thymic Epithelial Cell Culture ACS biomaterials science & engineering 2023-04-19 [PMID: 37074315]
Beamish EL, Johnson J, Shih B et al. Delay in loop ileostomy reversal surgery does not impact upon post-operative clinical outcomes. Complications are associated with an increased loss of microflora in the defunctioned intestine Gut microbes 2023-04-14 [PMID: 37055940] (WB, Human)	WB	Human
Gao AY, Diaz Espinosa AM, Nguyen BBN et al. Dopamine Receptor D1 Is Exempt from Transforming Growth Factor ?-Mediated Antifibrotic G Protein-Coupled Receptor Landscape Tampering in Lung Fibroblasts The Journal of pharmacology and experimental therapeutics 2023-09-01 [PMID: 37024146]
Liu B, Jie X, Deng J et al. Bupi Yishen formula may prevent kidney fibrosis by modulating fatty acid metabolism in renal tubules Phytomedicine : international journal of phytotherapy and phytopharmacology 2023-03-16 [PMID: 37001297] (IHC-P, Rat)	IHC-P	Rat
Takács R, Vágó J, Póliska S et al. The temporal transcriptomic signature of cartilage formation Nucleic acids research 2023-05-08 [PMID: 36987858] (IHC-P, Chicken) Details: 1:500 IHC-P dilution	IHC-P	Chicken
Li K, Huo Q, Dimmitt NH et al. Osteosarcoma-enriched transcripts paradoxically generate osteosarcoma-suppressing extracellular proteins eLife 2023-03-21 [PMID: 36943734] (ELISA, IP, WB)	ELISA, IP, WB
Volkova E, Procell L, Kong L et al. Vascular stiffening in aging females with a hypertension induced HIF2A gain of function mutation Bioengineering & Translational Medicine 2022-10-03 [PMID: 36925716] (IF/IHC, Mouse)	IF/IHC	Mouse
Li S, Livingston MJ, Ma Z et al. Tubular cell senescence promotes maladaptive kidney repair and chronic kidney disease after cisplatin nephrotoxicity JCI insight 2023-03-14 [PMID: 36917180] (IHC-P, WB, Mouse)	IHC-P, WB	Mouse
Geiduschek EK, Milne PD, Mzyk P et al. TLR4 signaling modulates extracellular matrix production in the lamina cribrosa Front Ophthalmol (Lausanne) 2022-08-19 [PMID: 36911656] (ICC/IF)	ICC/IF
Yuri G, Sanhueza S, Paredes A et al. Deleterious liver-adipose crosstalk in obesity: Hydroethanolic extract of Lampaya medicinalis Phil. (Verbenaceae) counteracts fatty acid-induced fibrotic marker expression in human hepatocytes Molecular and cellular endocrinology 2023-03-15 [PMID: 36736687]
Alaghemand H, Esmaeili B, Firouz P. A comparative study of the preventive effect of chlorhexidine o. 12% and nano zinc oxide particles on the distraction of collagen scaffolding of the hybrid layer by two immunohistochemistry and microleakage tests. Dentistry and Medical research. 2014-09-21 (IHC-P, Human) Details: Collagen I alpha 1 antibody used for IHC-P on 4um sections of dentin extracted from human subject's molars and premolar teeth with no caries and visible anatomic defects (Figure 2).	IHC-P	Human
Tibaldi E, Brocca A, Sticca A et al. Fam20C-mediated phosphorylation of osteopontin is critical for its secretion but dispensable for its action as a cytokine in the activation of hepatic stellate cells in liver fibrogenesis FASEB j. Nov 29 2019 (WB, Rat)	WB	Rat
Zou CY, Hu JJ, Lu D et al. A self-fused hydrogel for the treatment of glottic insufficiency through outstanding durability, extracellular matrix-inducing bioactivity and function preservation Bioactive Materials 2023-06-01 [PMID: 36582347] (IHC)	IHC
Cook J. Toward a Mechanistic Understanding of Hepatic Insulin Action and Resistance. Thesis. 2014-01-01 (WB, Mouse)	WB	Mouse
Rodriguez-Rivera V. Novel Biofabrication Technologies to Recapitulate In Vivo Geometries in Collagen Hydrogels Thesis. 2014-12-15 (WB)	WB
Shao Q, Feng Y, Wang W et al. Drug carrier for sustained release of withaferin A for pancreatic cancer treatment J Mater Sci 2019 Oct 23
DeRoo E, Zhou T, Yang H et al. A vein wall cell atlas of murine venous thrombosis determined by single-cell RNA sequencing Communications biology 2023-01-31 [PMID: 36721040] (IHC, Mouse)	IHC	Mouse
Melchor SJ, Hatter JA, Castillo EALT, Saunders CM Cachexia and fibrosis are costs of chronic IL-1R-mediated disease tolerance in T. gondii infection bioRxiv
Shao Q, Feng Y, Wang W et al. Drug carrier for sustained release of withaferin A for pancreatic cancer treatment J Mater Sci
Zhang Y, Jeong H, Mori K et al. Vascular endothelial growth factor from retinal pigment epithelium is essential in choriocapillaris and axial length maintenance PNAS Nexus 2022-08-24 [PMID: 36714840] (IF/IHC, Mouse)	IF/IHC	Mouse
Arias-Garcia M, Rickman R, Sero J The cell-cell adhesion protein JAM3 determines nuclear deformability by regulating microtubule organization biorxiv.org 2019-01-01 (ICC/IF, Human)	ICC/IF	Human
Paul K, Darzi S, Del Borgo M et al. Vaginal delivery of tissue engineered endometrial mesenchymal stem/stromal cells in an aloe vera-alginate hydrogel alleviates maternal simulated birth injury Applied Materials Today 2021-03-01 (ICC/IF, Human)	ICC/IF	Human
Lee SY, Kim S, Choi I et al. Inhibition of 11 beta -hydroxysteroid dehydrogenase 1 relieves fibrosis through depolarizing of hepatic stellate cell in NASH Cell death & disease 2022-11-29 [PMID: 36446766] (WB, Human) Details: Dilutions: 1:500	WB	Human
Kwon T, Moon D, Kim J Et Al. Application of 630-nm and 850-nm Light-emitting Diodes and Microcurrent to Accelerate Collagen and Elastin Deposition in Porcine Skin Medical Lasers 2021-06-30 (IHC-P)	IHC-P
Scaria S Understanding the Mechanisms of Epimorphic Regeneration in the Mammalian Tympanic Membrane Thesis 2022-01-01 (Mouse)		Mouse
Alves AL, Carvalho AC, Machado I et al. Cell-Laden Marine Gelatin Methacryloyl Hydrogels Enriched with Ascorbic Acid for Corneal Stroma Regeneration Bioengineering (Basel, Switzerland) 2023-01-04 [PMID: 36671634] (ICC/IF, Human) Details: Dilution used in ICC 1:200	ICC/IF	Human
Latif A, Fisher LE, Dundas AA et al. Microparticles Decorated with Cell-Instructive Surface Chemistries Actively Promote Wound Healing Advanced materials (Deerfield Beach, Fla.) 2022-11-28 [PMID: 36440539] (IHC-P, Human)	IHC-P	Human
Sun X, Zhou L, Han Y et al. Scutellarin Attenuates Doxorubicin-Induced Cardiotoxicity by Inhibiting Myocardial Fibrosis, Apoptosis and Autophagy in Rats Chemistry & biodiversity 2022-11-23 [PMID: 36419360]
Taniguchi Y, Ouhara K, Kitagawa M et al. Periapical lesion following Cnm-positive Streptococcus mutans pulp infection worsens cerebral hemorrhage onset in an SHRSP rat model Clinical and experimental immunology 2022-11-11 [PMID: 36368020] (WB, Human)	WB	Human
Mi YB, Liu XH, Wang WS et al. ER-phagy Is Involved in the Degradation of Collagen I by IL-1B in Human Amnion in Parturition Journal of immunology (Baltimore, Md. : 1950) 2022-10-26 [PMID: 36288908] (WB, Human)	WB	Human
Lewis A, SAnchez S, Berti G et al. Small-molecule Wnt inhibitors are a potential novel therapy for intestinal fibrosis in Crohns disease Clinical science (London, England : 1979) 2022-10-14 [PMID: 36156078] (ICC/IF, Human)	ICC/IF	Human
Xu J, Kausalya PJ, Ong AGM et al. ZO-2/Tjp2 suppresses Yap and Wwtr1/Taz-mediated hepatocyte to cholangiocyte transdifferentiation in the mouse liver npj Regenerative Medicine 2022-09-23 [PMID: 36151109] (WB, B/N)	WB, B/N
Youssef ME, Abdel-Reheim MA, Morsy MA et al. Ameliorative Effect of Dabigatran on CFA-Induced Rheumatoid Arthritis via Modulating Kallikrein-Kinin System in Rats International Journal of Molecular Sciences 2022-09-07 [PMID: 36142208] (WB)	WB
Nanda I, Schr�der SK, Steinlein C et al. Rat Hepatic Stellate Cell Line CFSC-2G: Genetic Markers and Short Tandem Repeat Profile Useful for Cell Line Authentication Cells 2022-09-16 [PMID: 36139474] (WB)	WB
Gong H, Chen L, He Y et al. Pleural thickening induced by Glaesserella parasuis infection was linked to increased collagen and elastin Frontiers in cellular and infection microbiology 2022-08-11 [PMID: 36034702] (IHC-P, Porcine)	IHC-P	Porcine
Zhou YH, Guo Y, Zhu JY et al. Spheroid co-culture of BMSCs with osteocytes yields ring-shaped bone-like tissue that enhances alveolar bone regeneration Scientific reports 2022-08-27 [PMID: 36030312] (IHC-P, Mouse) Details: IHC-P 1:100	IHC-P	Mouse
Caporarello N, Lee J, Pham TX et al. Dysfunctional ERG signaling drives pulmonary vascular aging and persistent fibrosis Nature communications 2022-07-25 [PMID: 35879310] (WB, Human)	WB	Human
Hadjisavva R, Anastasiou O, Ioannou PS et al. Adherens junctions stimulate and spatially guide integrin activation and extracellular matrix deposition Cell reports 2022-07-19 [PMID: 35858563] (ICC, Human)	ICC	Human
Patil SV, Kasetti RB, Millar JC, Zode GS. A Novel Mouse Model of TGF?2-Induced Ocular Hypertension Using Lentiviral Gene Delivery International Journal of Molecular Sciences 2022-06-21 [PMID: 35805889] (WB)	WB
I Nanda, C Steinlein, T Haaf, EM Buhl, DG Grimm, SL Friedman, SK Meurer, SK Schröder, R Weiskirche Genetic Characterization of Rat Hepatic Stellate Cell Line HSC-T6 for In Vitro Cell Line Authentication Cells, 2022-05-29;11(11):. 2022-05-29 [PMID: 35681478]
JJ Wu, ZL Sun, SY Liu, ZH Chen, ZD Yuan, ML Zou, YY Teng, YY Li, DY Guo, FL Yuan The ASIC3-M-CSF-M2 macrophage-positive feedback loop modulates fibroblast-to-myofibroblast differentiation in skin fibrosis pathogenesis Cell Death & Disease, 2022-06-06;13(6):527. 2022-06-06 [PMID: 35661105]
Ron C Vinestock, Neta Felsenthal, Eran Assaraf, Eldad Katz, Sarah Rubin, Lia Heinemann-Yerushalmi, Sharon Krief, Nili Dezorella, Smadar Levin-Zaidman, Michael Tsoory, Stavros Thomopoulos, Elazar Zelzer Neonatal Enthesis Healing Involves Noninflammatory Acellular Scar Formation through Extracellular Matrix Secretion by Resident Cells. The American journal of pathology 2022-08-16 [PMID: 35659946]
Li X, Yong T, Wei Z et al. Reversing insufficient photothermal therapy-induced tumor relapse and metastasis by regulating cancer-associated fibroblasts Nature communications 2022-05-19 [PMID: 35589680] (IF/IHC, Mouse, Human)	IF/IHC	Mouse, Human
Kim MK, Yoon JA, Yoon SY et al. Human Platelet-Rich Plasma Facilitates Angiogenesis to Restore Impaired Uterine Environments with Asherman's Syndrome for Embryo Implantation and Following Pregnancy in Mice Cells 2022-05-05 [PMID: 35563855] (IHC)	IHC
Xue W, Yu SY, Kuss M et al. 3D bioprinted white adipose model forin vitrostudy of cancer-associated cachexia induced adipose tissue remodeling Biofabrication 2022-05-26 [PMID: 35504266]
Park HH, Kim YM, Anh Hong LT et al. Dual-functional hydrogel system for spinal cord regeneration with sustained release of arylsulfatase B alleviates fibrotic microenvironment and promotes axonal regeneration Biomaterials 2022-05-01 [PMID: 35461098] (IF/IHC, Rat)	IF/IHC	Rat
Pothiawala A, Sahbazoglu BE, Ang BK et al. GDF5 + chondroprogenitors derived from human pluripotent stem cells preferentially form permanent chondrocytes Development (Cambridge, England) 2022-04-22 [PMID: 35451016]
Lavin RC, Tan S. Spatial relationships of intra-lesion heterogeneity in Mycobacterium tuberculosis microenvironment, replication status, and drug efficacy PLOS Pathogens 2022-03-28 [PMID: 35344572]
Aidos L, Modina SC, Millar VRH et al. Meniscus Matrix Structural and Biomechanical Evaluation: Age-Dependent Properties in a Swine Model Bioengineering (Basel, Switzerland) 2022-03-15 [PMID: 35324808] (IF/IHC, WB, Porcine)	IF/IHC, WB	Porcine
Lee M, Kim H, Kwak I et al. Immunohistochemical Analysis of Postburn Scars following Treatment Using Dermal Substitutes Analytical Cellular Pathology 2022-02-25 [PMID: 35251908]
Trott AJ, Greenwell BJ, Karhadkar TR et al. Lack of food intake during shift work alters the heart transcriptome and leads to cardiac tissue fibrosis and inflammation in rats BMC biology 2022-03-03 [PMID: 35236346] (IF/IHC, Rat)	IF/IHC	Rat
Li C, Yang M, Qu Z et al. Effect of electroacupuncture on the degradation of collagen in pelvic floor supporting tissue of stress urinary incontinence rats International urogynecology journal 2022-02-28 [PMID: 35226143] (WB, Rat)	WB	Rat
Rusu-Nastase E, Lupan A, Marinescu C et al. MiR-29a Increase in Aging May Function as a Compensatory Mechanism Against Cardiac Fibrosis Through SERPINH1 Downregulation Frontiers in Cardiovascular Medicine 2022-01-18 [PMID: 35118144] (ICC/IF, Mouse)	ICC/IF	Mouse
Srinivasan MP, Bhopale KK, Caracheo AA et al. Exposure to binge ethanol and fatty acid ethyl esters exacerbates chronic ethanol-induced pancreatic injury in hepatic alcohol dehydrogenase deficient deer mice American journal of physiology. Gastrointestinal and liver physiology 2022-01-05 [PMID: 34984929] (WB, Mouse)	WB	Mouse
Wang R, Kairen C, Li L et al. Overexpression of NDUFV1 alleviates renal damage by improving mitochondrial function in unilateral ureteral obstruction model mice Cell biology international 2021-12-22 [PMID: 34936716]
Zhang D, Liu B, Jie X et al. Uncovering Bupi Yishen Formula Pharmacological Mechanisms Against Chronic Kidney Disease by Network Pharmacology and Experimental Validation Frontiers in Pharmacology 2021-11-15 [PMID: 34867380] (WB, B/N)	WB, B/N
Keller CR, Hu Y, Ruud KF Et al. Human Breast Extracellular Matrix Microstructures and Protein Hydrogel 3D Cultures of Mammary Epithelial Cells Cancers 2021-11-22 [PMID: 34831010] (ICC/IF, Human)	ICC/IF	Human
Kasetti RB, Maddineni P, Kodati B Et al. Astragaloside IV Attenuates Ocular Hypertension in a Mouse Model of TGF beta 2 Induced Primary Open Angle Glaucoma International journal of molecular sciences 2021-11-19 [PMID: 34830390] (ICC/IF, Human)	ICC/IF	Human
Jiang X, Wojtkiewicz M, Patwardhan C et al. The effects of maturation and aging on the rotator cuff tendon-to-bone interface The FASEB Journal 2022-03-18 [PMID: 34822203] (B/N)	B/N
de Sousa BM, Correia CR, Ferreira JAF Et al. Capacitive interdigitated system of high osteoinductive/conductive performance for personalized acting-sensing implants NPJ Regenerative medicine 2021-11-23 [PMID: 34815414] (WB, Mouse)	WB	Mouse
Lee J, Ung A, Kim H Et al. Engineering liver microtissues to study the fusion of HepG2 with mesenchymal stem cells and invasive potential of fused cells Biofabrication 2021-11-30 [PMID: 34740205]
Miura Y, Lam M, Bourke JE, Kanazawa S Bimodal fibrosis in a novel mouse model of bleomycin-induced usual interstitial pneumonia Life science alliance 2022-01-01 [PMID: 34728556] (IHC-P, Mouse)	IHC-P	Mouse
Huang LT, Chou HC, Chen CM. Inhibition of FABP4 attenuates hyperoxia-induced lung injury and fibrosis via inhibiting TGF- beta signaling in neonatal rats Journal of cellular physiology 2021-10-28 [PMID: 34708870] (Rat)		Rat
Maddineni P, Kasetti RB, Kodati B et al. Sodium 4-Phenylbutyrate Reduces Ocular Hypertension by Degrading Extracellular Matrix Deposition via Activation of MMP9 International journal of molecular sciences 2021-09-18 [PMID: 34576258] (ICC/IF, Mouse)	ICC/IF	Mouse
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Townsend J, Zabel T, Feng Y, Wang J. Effects of tissue processing on bioactivity of cartilage matrix-based hydrogels encapsulating osteoconductive particles. Biomed. Mater. 2018-02-07 [PMID: 29411714] (IF/IHC, Rat)	IF/IHC	Rat
Rogerson C, Gissen P. VPS33B and VIPAR are essential for epidermal lamellar body biogenesis and function. Biochim. Biophys. Acta. 2018-01-30 [PMID: 29409756] (IF/IHC, Mouse)	IF/IHC	Mouse
Wu X, Zhi F, Lun W, Deng Q. Baicalin inhibits PDGF-BB-induced hepatic stellate cell proliferation, apoptosis, invasion, migration and activation via the miR-3595/ACSL4 axis. Int. J. Mol. Med. 2018-04-01 [PMID: 29393361] (WB, Rat)	WB	Rat
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Kasetti RB, Maddineni P, Millar JC et al. Increased synthesis and deposition of extracellular matrix proteins leads to endoplasmic reticulum stress in the trabecular meshwork Sci Rep. 2017-11-02 [PMID: 29097767] (ICC/IF, Human)	ICC/IF	Human
Kaukonen R. Filopodia and stromal extracellular matrix as regulators of cancer cell invasion and growth. Thesis. (ICC/IF, Human)	ICC/IF	Human
Xue W, Lee D, Kong Y et al. A Facile Strategy for the Fabrication of Cell?Laden Porous Alginate Hydrogels based on Two?Phase Aqueous Emulsions Advanced Functional Materials 2023-06-02 (IHC)	IHC
Biancacci I, De Santis D, Rama E et al. Repurposing Tamoxifen for Tumor Microenvironment Priming and Enhanced Tumor?Targeted Drug Delivery Advanced Therapeutics 2023-07-19 (IHC-Fr)	IHC-Fr
Kasetti RB, Maddineni P, Patel P et al. Transforming growth factor B2 (TGFB2) signaling plays a key role in glucocorticoid-induced ocular hypertension J. Biol. Chem. 2018-05-09 [PMID: 29743238] (Mouse)		Mouse
Joshi S, Wang W, Khan SR. Transcriptional study of hyperoxaluria and calcium oxalate nephrolithiasis in male rats: Inflammatory changes are mainly associated with crystal deposition PLoS ONE. 2017-11-01 [PMID: 29091707] (IHC-P, Rat)	IHC-P	Rat
Kaukonen R, Jacquemet G, Hamidi H, Ivaska J. Cell-derived matrices for studying cell proliferation and directional migration in a complex 3D microenvironment Nat Protoc. 2017-11-01 [PMID: 29048422] (ICC/IF)	ICC/IF
Lee DJ, Lee YT, Zou R et al. Polydopamine-Laced Biomimetic Material Stimulation of Bone Marrow Derived Mesenchymal Stem Cells to Promote Osteogenic Effects. Sci Rep. 2017-10-11 [PMID: 29021583] (ICC/IF, Rat)	ICC/IF	Rat
Gai Z, Chu L, Xu Z et al. Farnesoid X receptor activation protects the kidney from ischemia-reperfusion damage Sci Rep 2017-08-29 [PMID: 28852062] (IHC-P, Mouse)	IHC-P	Mouse
Whatcott CJ, Ng S, Barrett MT et al. Inhibition of ROCK1 kinase modulates both tumor cells and stromal fibroblasts in pancreatic cancer PLoS ONE 2017-08-25 [PMID: 28841710] (IHC-P, Mouse)	IHC-P	Mouse
Chen X, Li W, Li Y et al. Elevated serum antibody against Schistosoma japonicum HSP60 as a promising biomarker for liver pathology in schistosomiasis Sci Rep 2017-08-10 [PMID: 28798366] (IHC-P, Mouse)	IHC-P	Mouse
Hino K, Horigome K, Nishio M et al. Activin-A enhances mTOR signaling to promote aberrant chondrogenesis in fibrodysplasia ossificans progressiva J. Clin. Invest. 2017-07-31 [PMID: 28758906] (IHC-P, Human)	IHC-P	Human
Doebar S C, Sieuwerts A M et al. Gene Expression Differences between Ductal Carcinoma in Situ with and without Progression to Invasive Breast Cancer. Am J Pathol 2017-01-07 [PMID: 28634007] (IF/IHC, Human)	IF/IHC	Human
Tombulturk FK, Kasap M, Tuncdemir M et al. Effects of Lucilia sericata on wound healing in streptozotocin-induced diabetic rats and analysis of its secretome at the proteome level. Hum Exp Toxicol. 2017-01-01 [PMID: 28621210] (IF/IHC)	IF/IHC
L Marrero, J Simkin, M Sammarco, K Muneoka Fibroblast reticular cells engineer a blastema extracellular network during digit tip regeneration in mice Regeneration (Oxf), 2017-05-03;4(2):69-84. 2017-05-03 [PMID: 28616246]
Mahdy MAA, Warita K, Hosaka YZ. Effects of transforming growth factor-B1 treatment on muscle regeneration and adipogenesis in glycerol-injured muscle. Anim. Sci. J. 2017-06-06 [PMID: 28585769]
Haak AJ, Girtman MA, Ali MF et al. Phenylpyrrolidine structural mimics of pirfenidone lacking antifibrotic activity: A new tool for mechanism of action studies. Eur. J. Pharmacol. 2017-05-30 [PMID: 28576410] (Human)		Human
Pan R, Zhang Y, Zheng M et al. Hydroxysafflor Yellow A Suppresses MRC-5 Cell Activation Induced by TGF-b1 by Blocking TGF-b1 Binding to TbRII. Front Pharmacol 2017-05-29 [PMID: 28553231] (ICC/IF, WB, Human)	ICC/IF, WB	Human
Lugenbiel P, Wenz F, Govorov K et al. Atrial myofibroblast activation and connective tissue formation in a porcine model of atrial fibrillation and reduced left ventricular function. Life Sci. 2017-05-22 [PMID: 28546006] (Porcine)		Porcine
Gerarduzzi C, Kumar RK, Trivedi P et al. Silencing SMOC2 ameliorates kidney fibrosis by inhibiting fibroblast to myofibroblast transformation. JCI Insight. 2017-04-20 [PMID: 28422762] (WB, Human)	WB	Human
Hernandez H, Medina-Ortiz WE, Luan T et al. Crosstalk Between Transforming Growth Factor Beta-2 and Toll-Like Receptor 4 in the Trabecular Meshwork. Invest. Ophthalmol. Vis. Sci. 2017-03-01 [PMID: 28346614] (ICC/IF, Human)	ICC/IF	Human
Mi Y, Wang W et al. Autophagic Degradation of Collagen 1A1 by Cortisol in Human Amnion Fibroblasts. Endocrinology 2017-01-04 [PMID: 28323983] (WB, Human)	WB	Human
Liu R, Das B, Xiao W et al. A Novel Inhibitor of Homeodomain Interacting Protein Kinase 2 Mitigates Kidney Fibrosis through Inhibition of the TGF-b1/Smad3 Pathway. J. Am. Soc. Nephrol. 2017-02-20 [PMID: 28220029] (WB)	WB
Patel GC, Phan TN, Maddineni P et al. Dexamethasone-Induced Ocular Hypertension in Mice: Effects of Myocilin and Route of Administration. Am. J. Pathol. 2017-02-03 [PMID: 28167045]
Sansalone Salvatore, Loreto Carla, Leonardi Rosario et al. Microsurgical tunica albuginea transplantation in an animal model. Asian Journal of Andrology [PMID: 28139472] (IF/IHC, Rat)	IF/IHC	Rat
Jakob M. Townsend, S. Connor Dennis, Jonathan Whitlow et al. Colloidal Gels with Extracellular Matrix Particles and Growth Factors for Bone Regeneration in Critical Size Rat Calvarial Defects. The AAPS Journal. [PMID: 28138909] (IF/IHC, Rat)	IF/IHC	Rat
Hellewell AL, Rosini S, Adams JC. A Rapid, Scalable Method for the Isolation, Functional Study, and Analysis of Cell-derived Extracellular Matrix J Vis Exp 2017-01-04 [PMID: 28117783] (ICC/IF, Human)	ICC/IF	Human
Malinverno M, Corada M, Ferrarini L et al. Peg3/PW1 is a marker of a subset of vessel associated endothelial progenitors Stem Cells 2017-01-16 [PMID: 28090691] (WB, ICC/IF, Mouse)	WB, ICC/IF	Mouse
Lugenbiel P, Wenz F, Syren P et al. TREK-1 (K2P2.1) K(+) channels are suppressed in patients with atrial fibrillation and heart failure and provide therapeutic targets for rhythm control. Basic Res. Cardiol. 2017-01-01 [PMID: 28005193] (Human)		Human
Peuhu E, Kaukonen R, Lerche M et al. SHARPIN regulates collagen architecture and ductal outgrowth in the developing mouse mammary gland. EMBO J. 2016-12-14 [PMID: 27974362] (WB, Mouse)	WB	Mouse
Yeonhwa Song, Se-hyuk Kim, Kang Mo Kim, Eun Kyung Choi, Joon Kim, Haeng Ran Seo Activated hepatic stellate cells play pivotal roles in hepatocellular carcinoma cell chemoresistance and migration in multicellular tumor spheroids Scientific Reports 2016-11-17 [PMID: 27853186]
Kasetti RB, Phan TN, Millar JC, Zode GS. Expression of Mutant Myocilin Induces Abnormal Intracellular Accumulation of Selected Extracellular Matrix Proteins in the Trabecular Meshwork. Invest. Ophthalmol. Vis. Sci. 2016-11-01 [PMID: 27820874] (Human)		Human
Makitsubo M, Adachi N, Nakasa T et al. Differences in joint morphology between the knee and ankle affect the repair of osteochondral defects in a rabbit model. J Orthop Surg Res. 2016-10-04 [PMID: 27716360] (IF/IHC, Rabbit)	IF/IHC	Rabbit
Cakir-Ozkan N, Eri S, Bekar E et al. The Use of Sequentially VEGF and BMP2 Releasing Biodegradable Scaffolds in Rabbit Mandibular Defects. J Oral Maxillofac Surg. 2016-08-27 [PMID: 27663536] (IF/IHC, Rabbit)	IF/IHC	Rabbit
Sakurai Y, Hada T, Yamamoto S et al. Remodeling of the Extracellular Matrix by Endothelial Cell-Targeting siRNA Improves the EPR-Based Delivery of 100 nm Particles. Mol Ther 2016-12-01 [PMID: 27633444]
WULANDARI E, JUSMAN SW, MOENADJAT Y et al. Expressions of Collagen I and III in Hypoxic Keloid Tissue Kobe J Med Sci. 2016-06-08 [PMID: 27604536]
Kaukonen R, Mai A, Georgiadou M et al. Normal stroma suppresses cancer cell proliferation via mechanosensitive regulation of JMJD1a-mediated transcription. Nat Commun. 2016-08-04 [PMID: 27488962] (ICC/IF, Human)	ICC/IF	Human
Lewis DM, Park KM, Tang V et al. Intratumoral oxygen gradients mediate sarcoma cell invasion. Proc. Natl. Acad. Sci. U.S.A. 2016-08-16 [PMID: 27486245] (ICC/IF, Mouse)	ICC/IF	Mouse
Granato M, Zompetta C, Vescarelli E et al. HCV derived from sera of HCV-infected patients induces pro-fibrotic effects in human primary fibroblasts by activating GLI2. Sci Rep. 2016-08-01 [PMID: 27476557] (ICC/IF, Human)	ICC/IF	Human
Banushi B, Forneris F, Straatman-Iwanowska A et al. Regulation of post-Golgi LH3 trafficking is essential for collagen homeostasis Nat Commun 2016-07-20 [PMID: 27435297] (IP)	IP
Xie T, Liang J, Liu N et al. Transcription factor TBX4 regulates myofibroblast accumulation and lung fibrosis J. Clin. Invest. 2016-08-01 [PMID: 27400124]
Chen HJ, Wei Z, Sun J et al. A recellularized human colon model identifies cancer driver genes Nat. Biotechnol. 2016-07-11 [PMID: 27398792]
Yang Jie, Xiang Fei, Cai Peng-Cheng et al. Activation of calpain by renin-angiotensin system in pleural mesothelial cells mediates tuberculous pleural fibrosis. Am J Physiol Lung Cell Mol Physiol 2016-01-01 [PMID: 27261452] (WB, Human)	WB	Human
Lee DJ, Park Y, Hu WS, Ko CC. Osteogenic Potential of Multipotent Adult Progenitor Cells for Calvaria Bone Regeneration. Adv Med. 2016-05-30 [PMID: 27239552] (IF/IHC, Rat)	IF/IHC	Rat
Chen PY, Qin L, Li G et al. Smooth muscle FGF/TGFbeta cross talk regulates atherosclerosis progression. EMBO Mol Med. 2016-05-13 [PMID: 27189169] (IF/IHC, Mouse)	IF/IHC	Mouse
Deng HW, Tian Y, Zhou XJ et al. Effect of Bilberry Extract on Development of Form-Deprivation Myopia in the Guinea Pig. J Ocul Pharmacol Ther 2016-05-01 [PMID: 26982283]
Hunziker EB, Lippuner K, Keel MJ et al. A novel organ-slice culturing system to simulate meniscal repair: Proof of concept using a synovium-based pool of meniscoprogenitor cells. J. Orthop. Res. 2016-01-21 [PMID: 26790377] (IHC-P, Human)	IHC-P	Human
Ying R, Wang XQ, Yang Y et al. Hydrogen sulfide suppresses endoplasmic reticulum stress-induced endothelial-to-mesenchymal transition through Src pathway. Life Sci. 2016-01-01 [PMID: 26656263] (WB, Human)	WB	Human
Chen PY, Qin L, Baeyens N et al. Endothelial-to-mesenchymal transition drives atherosclerosis progression. J Clin Invest 2015-10-26 [PMID: 26517696] (WB)	WB
Schmidt JB, Tranquillo RT. Cyclic Stretch and Perfusion Bioreactor for Conditioning Large Diameter Engineered Tissue Tubes. Ann Biomed Eng. 2015-08-26 [PMID: 26307332] (IHC-Fr, Human)	IHC-Fr	Human
Bertolo A, Arcolino F, Capossela S et al. Growth factors cross-linked to collagen microcarriers promote expansion and chondrogenic differentiation of human mesenchymal stem cells. Tissue Eng Part A. 2015-07-29 [PMID: 26222829] (Human)		Human
Jenkitkasemwong S, Wang CY, Coffey R et al. SLC39A14 Is Required for the Development of Hepatocellular Iron Overload in Murine Models of Hereditary Hemochromatosis. Cell Metab 2015-07-07 [PMID: 26028554] (WB)	WB
Rana Indrajeetsinh, Kompa Andrew R, Skommer Joanna et al. Contribution of microRNA to pathological fibrosis in cardio-renal syndrome: impact of uremic toxins. Physiol Rep 2015-01-01 [PMID: 25896982] (WB, Rat)	WB	Rat
Katsutsugu Umeda, Hirotsugu Oda, Qing Yan, Nadine Matthias, Jiangang Zhao, Brian R. Davis, Naoki Nakayama Long-Term Expandable SOX9 + Chondrogenic Ectomesenchymal Cells from Human Pluripotent Stem Cells Stem Cell Reports 2015-03-26 [PMID: 25818812]
Shetty R, Sathyanarayanamoorthy A, Ramachandra RA et al. Attenuation of lysyl oxidase and collagen gene expression in keratoconus patient corneal epithelium corresponds to disease severity. Mol Vis 2015-01-01 [PMID: 25593510] (IF/IHC)	IF/IHC
Weidenhamer NK, Moore DL, Lobo FL et al. Influence of culture conditions and extracellular matrix alignment on human mesenchymal stem cells invasion into decellularized engineered tissues. J Tissue Eng Regen Med. 2015-01-02 [PMID: 25556358]
Ikezumi Y, Suzuki T, Yamada T et al. Alternatively activated macrophages in the pathogenesis of chronic kidney allograft injury. Pediatr. Nephrol. 2014-12-09 [PMID: 25487670] (IHC-P, Human) Details: Collagen I alpha 1 antibody used for IHC-P on human kidney allograft protocol biopsies (Fig 1)	IHC-P	Human
Duarte AS, Cavaleiro E, Pereira C et al. Aeromonas piscicola AH-3 expresses an extracellular collagenase with cytotoxic properties. Lett. Appl. Microbiol. 2014-12-02 [PMID: 25443157] (WB) Details: Collagen I alpha 1 antibody used for Far-Western blot analysis on cell-free supernatants (CFSs) from Aeromonas piscicola AH-3 and Aeromonas piscicola AH-3::colAh knockout mutants, with collagen type I as a positive control (Figure 1C).	WB
Gehmlich K, Dodd MS, William Allwood J et al. Changes in the cardiac metabolome caused by perhexiline treatment in a mouse model of hypertrophic cardiomyopathy. Mol Biosyst. 2014-12-01 [PMID: 25437646] (WB, Mouse) Details: Collagen I alpha 1 antibody used in WB for examining the Collagen 1 protein levels in perhexiline- and placebo-treated Mybpc3 KI mice compared to WT, with endogenous protein calsequestrin (CSQ) used as a normalization control. WB data is shown in Figure S4A.	WB	Mouse
Fukuda M, Aoki T, Manabe T et al. Exacerbation of Intracranial Aneurysm and Aortic Dissection in Hypertensive Rat Treated With the Prostaglandin F-Receptor Antagonist AS604872. J. Pharmacol. Sci. 2014-10-23 [PMID: 25341845] (IF/IHC, Human, Rat)	IF/IHC	Human, Rat
Ramani K, Donoyan S, Tomasi Ml, Park S. Role of Methionine Adenosyltransferase Alpha2 and B Phosphorylation and Stabilization in Human Hepatic Stellate Cell Trans-Differentiation. J. Cell. Physiol. 2014-10-07 [PMID: 25294683] (WB, Human)	WB	Human
Di Giancamillo A, Deponti D, Addis A et al. Meniscus maturation in the swine model: changes occurring along with anterior to posterior and medial to lateral aspect during growth. J Cell. Mol. Med. 2014-09-12 [PMID: 25216283]
Elsner A,Lange F,Fitzner B et al. Distinct antifibrogenic effects of erlotinib, sunitinib and sorafenib on rat pancreatic stellate cells World J. Gastroenterol. 2014-06-28 [PMID: 24976727] (WB, Rat) Details: Collagen I antibody used for WB on protein extracts from rat's pancreatic stellate cells/ PSCs using PVDF membrane protein transfer and LI-COR -Odyssey detection. Figure 4A - type?I?collagen 150 kDa expression levels in Rat's PSCs treated or not with 48h of 10uM/L erlotinib, sorafenib or sunitinib.	WB	Rat
Jobara Kanta, Kaido Toshimi, Hori Tomohide et al. Whey-hydrolyzed peptide-enriched immunomodulating diet prevents progression of liver cirrhosis in rats. Nutrition. 2014-02-28 [PMID: 24976428] (Rat)		Rat
Torres PM, Vieira SI, Cerqueira AR et al. Effects of Mn-doping on the structure and biological properties of beta-tricalcium phosphate. J. Inorg. Biochem. 2014-04-03 [PMID: 24747361] (ICC/IF, WB, Mouse)	ICC/IF, WB	Mouse
Nijhuis A, Biancheri P, Lewis A et al. In Crohn's disease fibrosis reduced expression of the miR-29 family enhances collagen expression in intestinal fibroblasts. Clin. Sci. 2014-03-18 [PMID: 24641356] (ICC/IF, Human)	ICC/IF	Human
Majumder K, Chakrabarti S, Morton JS et al. Egg-Derived Tri-Peptide IRW Exerts Antihypertensive Effects in Spontaneously Hypertensive Rats. PLoS One. 2013-11-29 [PMID: 24312436] (ICC/IF, IHC-Fr, Rat)	ICC/IF, IHC-Fr	Rat
Rebours V, Albuquerque M, Sauvanet A et al. Hypoxia Pathways and Cellular Stress Activate Pancreatic Stellate Cells: Development of an Organotypic Culture Model of Thick Slices of Normal Human Pancreas. PLoS One. 2013-09-30 [PMID: 24098783] (IHC-P, Human)	IHC-P	Human
Seet LF, Finger SN, Chu SW et al. Novel Insight into the Inflammatory and Cellular Responses Following Experimental Glaucoma Surgery: A Roadmap for Inhibiting Fibrosis. Curr Mol Med 2013-06-07 [PMID: 23651348]
Gilkes DM, Chaturvedi P, Bajpai S et al. Collagen prolyl hydroxylases are essential for breast cancer metastasis. Cancer Res 2013-06-01 [PMID: 23539444] (WB, Human)	WB	Human
Ni J, Dong Z, Han W et al. The Role of RhoA and Cytoskeleton in Myofibroblast Transformation in Hyperoxic Lung Fibrosis Free Radic Biol Med 2013-03-18 [PMID: 23517783] (ICC/IF, WB, IHC-P, Mouse, Human)	ICC/IF, WB, IHC-P	Mouse, Human
Gilkes DM, Bajpai S, Chaturvedi P et al. HIF-1 Promotes Extracellular Matrix Remodeling under Hypoxic Conditions by Inducing P4HA1, P4HA2, and PLOD2 Expression in Fibroblasts. J Biol Chem 2013-02-19 [PMID: 23423382] (WB, Human)	WB	Human
Gilkes DM, Bajpai S, Wong CC et al. Procollagen lysyl hydroxylase 2 is essential for hypoxia-induced breast cancer metastasis. Mol Cancer Res 2013-05-01 [PMID: 23378577] (WB, Human)	WB	Human
Masuzaki R, Zhao SR, Csizmadia E et al. Scar formation and lack of regeneration in adult and neonatal liver after stromal injury Wound Repair Regen 2013-01-01 [PMID: 23228176] (IF/IHC, Mouse)	IF/IHC	Mouse
Chen PY, Qin L, Barnes C et al. FGF Regulates TGF-beta Signaling and Endothelial-to-Mesenchymal Transition via Control of let-7 miRNA Expression Cell Rep 2012-11-27 [PMID: 23200853] (IF/IHC, ICC/IF, Mouse)	IF/IHC, ICC/IF	Mouse
Weidenhamer NK, Tranquillo RT. Influence of Cyclic Mechanical Stretch and Tissue Constraints on Cellular and Collagen Alignment in Fibroblast-derived Cell Sheets Tissue Eng Part C Methods 2012-11-06 [PMID: 23126441] (IF/IHC, ICC/IF, Human)	IF/IHC, ICC/IF	Human
Wang B, Sun J, Qian S et al. Proliferation and differentiation of osteoblastic cells on silicon-doped TiO2 film deposited by cathodic arc Biomed Pharmacother 2012-09-27 [PMID: 23089479] (ICC/IF, WB, Human)	ICC/IF, WB	Human
Zhang S, Sun J, Xu Y et al. Biological Behavior of Osteoblast-like Cells on Titania and Zirconia Films Deposited by Cathodic Arc Deposition Biointerphases 2012-12-01 [PMID: 23055096] (ICC/IF, Human)	ICC/IF	Human
Gokce A, Yilmaz I, Bircan R et al. Synergistic Effect of TGF-beta1 And BMP-7 on Chondrogenesis and Extracellular Matrix Synthesis: An In Vitro Study Open Orthop J 2012-01-01 [PMID: 23002411] (WB, Human)	WB	Human
Pratap A, Singh S, Mundra V et al. Attenuation of early liver fibrosis by pharmacological inhibition of smoothened receptor signaling J Drug Target 2012-11-01 [PMID: 22994359] (WB, Rat)	WB	Rat
Geirsson A, Singh M, Ali R et al. Modulation of Transforming Growth Factor-beta Signaling and Extracellular Matrix Production in Myxomatous Mitral Valves by Angiotensin II Receptor Blockers Circulation 2012-09-11 [PMID: 22965982] (IF/IHC, Human)	IF/IHC	Human
Lai VK, Frey CR, Kerandi AM et al. Microstructural and Mechanical Differences Between Digested Collagen-Fibrin Co-Gels and Pure Collagen and Fibrin Gels Acta Biomater 2012-07-21 [PMID: 22828381] (ICC/IF, Rat)	ICC/IF	Rat
Lee HJ, Won JH, Doo SH et al. Inhibition of collagen deposit in obstructed rat bladder outlet by transplantation of superparamagnetic iron oxide-labeled human mesenchymal stem cells as monitored by molecular magnetic resonance imaging (MRI) Cell Transplant 2012-01-01 [PMID: 22449414] (WB, Rat)	WB	Rat
Zhou L, Wang L, Lu L, Jiang P, Sun H et al. Inhibition of miR-29 by TGF-beta-Smad3 Signaling through Dual Mechanisms Promotes Transdifferentiation of Mouse Myoblasts into Myofibroblasts PLoS ONE 2012-01-01 [PMID: 22438993] (WB, ICC/IF, Mouse)	WB, ICC/IF	Mouse
Remacle AG, Golubkov VS, Shiryaev SA, Dahl R, Stebbins JL, Chernov AV, Cheltsov AV, Pellecchia M, Strongin AY. Novel MT1-MMP Small-Molecule Inhibitors Based on Insights into Hemopexin Domain Function in Tumor Growth. Cancer Res;72(9):2339-49. 2012-05-01 [PMID: 22406620] (ICC/IF, IF/IHC, Mouse)	ICC/IF, IF/IHC	Mouse
Ferreira JR, Hirsch ML, Zhang L et al. Three-dimensional multipotent progenitor cell aggregates for expansion, osteogenic differentiation and 'in vivo' tracing with AAV vector serotype 6 Gene Ther 2012-03-08 [PMID: 22402320] (IHC-Fr, Rat)	IHC-Fr	Rat
Seet L-F, Tong L, Su R, Wong TT. Involvement of SPARC and MMP-3 in the Pathogenesis of Human Pterygium. Investigative Ophthalmology & Visual Science. 2012-01-04 [PMID: 22222271]
Mak KM, Kwong AJ, Chu E et al. Hepatic steatosis, fibrosis, and cancer in elderly cadavers. Anat Rec (Hoboken) 2012-01-01 [PMID: 22139908]
Ma W, Han W, Greer PA et al. Calpain mediates pulmonary vascular remodeling in rodent models of pulmonary hypertension, and its inhibition attenuates pathologic features of disease. The Journal of Clinical Investigation. 2011-10-17 [PMID: 22005303]
Deng Y, Chen B, Qi Y et al. The effects of levofloxacin on rabbit anterior cruciate ligament cells in vitro. Toxicology and Applied Pharmacology. 2011-08-27 [PMID: 21903125]
Golubkov VS, Chernov AV, Strongin AY. Intradomain cleavage of the inhibitory prodomain is essential to the pro-tumorigenic function of membrane type-1 matrix metalloproteinase (MT1-MMP) in vivo. J Biol Chem. 2011-08-08 [PMID: 21832072]
Seet LF, Su R, Toh LZ, Wong TT. In vitro analyses of the anti-fibrotic effect of SPARC silencing in human Tenon's fibroblasts: comparisons with mitomycin-C. J Cell Mol Med. 2011-07-31 [PMID: 21801304] (WB, Human)	WB	Human
Lee K, Kim H, Kim JM et al. Nacre-driven water-soluble factors promote wound healing of the deep burn Porcine skin by recovering angiogenesis and fibroblast function. Mol Biol Rep. 2011-06-19 [PMID: 21688145] (IF/IHC, Porcine)	IF/IHC	Porcine
Ahmann KA, Johnson SL, Hebbel RP, Tranquillo RT. Shear stress responses of adult blood outgrowth endothelial cells seeded on bioartificial tissue. Tissue Eng Part A;17(19-20):2511-21. 2011-10-01 [PMID: 21599543] (IF/IHC, Human)	IF/IHC	Human
Crawford JR, Pilling D, Gomer RH et al. Improved serum-free culture conditions for spleen-derived murine fibrocytes. J Immunol Methods 2010-12-01 [PMID: 20888336]
Ramirez Allan M, Wongtrakool Cherry, Welch Teresa et al. Vitamin D inhibition of pro-fibrotic effects of transforming growth factor beta1 in lung fibroblasts and epithelial cells. J Steroid Biochem Mol Biol 2010-01-01 [PMID: 19931390] (WB, Mouse)	WB	Mouse
Han Weihong, Wang Wei, Mohammed Kamal A, Su Yunchao. Alpha-defensins increase lung fibroblast proliferation and collagen synthesis via the beta-catenin signaling pathway. FEBS J 2009-01-01 [PMID: 19814765] (WB, Human)	WB	Human
Sotgia F, Del Galdo F, Casimiro MC et al. Caveolin-1-/- Null Mammary Stromal Fibroblasts Share Characteristics with Human Breast Cancer-Associated Fibroblasts. Am J Pathol;174(3):746-761. 2009-01-01 [PMID: 19234134]
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Hazra S, Xiong S, Wang J et al. Peroxisome proliferator-activated receptor gamma induces a phenotypic switch from activated to quiescent hepatic stellate cells. J Biol Chem 2004-03-01 [PMID: 14702344]
Stefanovic B, Schnabl B, Brenner DA et al. Inhibition of collagen alpha 1(I) expression by the 5' stem-loop as a molecular decoy. J Biol Chem 2002-05-01 [PMID: 11889120]
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Images	Ratings	Applications	Species	Date	Details
	5 reviewed by: Federica Gnudi	IHC-P	Rat	05/05/2022	View Summary Application Immunohistochemistry-Paraffin Sample Tested Rat Lung Tissue Species Rat Lot 47500
	5 reviewed by: Verified Customer	ICC	Human	04/23/2021	View Summary Application Immunocytochemistry Sample Tested chondrocytes Species Human Lot 44222
Enlarge	5 reviewed by: Verified Customer	IHC-P	Mouse	10/10/2019	View Summary Application Immunohistochemistry-Paraffin Sample Tested Mouse Pancreas Species Mouse Lot 42336
Enlarge	4 reviewed by: Verified Customer	IHC-P	Mouse	10/02/2019	View Summary Application Immunohistochemistry-Paraffin Sample Tested Balb/3T3 mouse embryonic fibroblast cell line Species Mouse Lot 40267
	5 reviewed by: Wangsheng Wang	WB	Human	05/30/2018	View Summary Application Western Blot Sample Tested whole cell extract Species Human Lot 35820
Enlarge	3 reviewed by: Verified Customer	IHC-P	Mouse	10/25/2017	View Summary Application Immunohistochemistry-Paraffin Sample Tested IHC on parrafin sections (mouse) Species Mouse Lot 38594
Enlarge	5 reviewed by: Verified Customer	WB	Human	09/27/2017	View Summary Application Western Blot Sample Tested Cell lysate from human trabecular meshwork Species Human Lot 38594
	4 reviewed by: Verified Customer	ICC	Feline	06/23/2017	View Summary Application Immunocytochemistry Sample Tested Adult small intestine Species Feline Lot 38594 Comments Comments 4% PFA fixed feline tissue
Enlarge	5 reviewed by: Jakob Townsend	IHC-P	Rat	02/20/2017	View Summary Application Immunohistochemistry-Paraffin Sample Tested Bone Species Rat Lot 37789
Enlarge	5 reviewed by: Verified Customer	IHC-P	Rat	07/20/2016	View Summary Application Immunohistochemistry-Paraffin Sample Tested rat colon Species Rat Lot 34015
Enlarge	4 reviewed by: Verified Customer	WB	Other	08/04/2015	View Summary Application Western Blot Species Other
Enlarge	4 reviewed by: Verified Customer	IF	Human	10/02/2014	View Summary Application Immunofluorescence Sample Tested primary human cardiac fibroblasts Species Human Lot 32011
Enlarge	4 reviewed by: Elizabeth Rendina-Ruedy	WB	Mouse	08/05/2013	View Summary Application Western Blot Sample Tested Mouse Flushed Femur and whole cell lysate MC3T3 Species Mouse
Enlarge	5 reviewed by: Verified Customer	IHC-Fr	Human	06/18/2013	View Summary Application Immunohistochemistry-Frozen Sample Tested HaCaT-ras A5-RT3 (SCC) tumor sections Species Human
Enlarge	5 reviewed by: Nathan Weidenhamer	ICC	Human	02/04/2013	View Summary Application Immunocytochemistry Sample Tested human dermal fibroblast derived cell sheet Species Human
Enlarge	5 reviewed by: Verified Customer	WB	Human	09/04/2012	View Summary Application Western Blot Sample Tested Fibroblast Cell Media Species Human

Array NB600-408

• Collagen I Antibodies
• Collagen I Protein