CHORDC1 Antibody - BSA Free

Cysteine and histidine-rich domain containing 1 (CHORDC1; CHP1) is a member of a novel family of highly conserved proteins. These proteins are factors in plant disease resistance, as well as animal development. Mammalian Chp-1 is a novel Hsp90-interacting protein that contains two CHORD domains and one CS domain. CHP-1 binds to the ATPase domain of Hsp90, but this interaction does not utilize ATP and ATPase- coupled conformational change of Hsp90 (PMID: 15642353). High ADP:ATP ratios in cell lysates appears to promote the interaction between CHP1 and Hsp90 (PMID: 19875381). Additionally, CHP-1 has been shown to be 63% homologous to Melusin; a muscle specific protein necessary for heart hypertrophy caused by mechanical burden (PMID12965203).

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 1 confirmed species: Human.

We have publications tested in 1 application: WB.

Showing Publications 1 - 3 of 3.

Publications using NBP1-78304	Applications	Species
Urabe F, Kosaka N et al. miR-26a regulates extracellular vesicle secretion from prostate cancer cells via targeting SHC4, PFDN4, and CHORDC1. Sci Adv 2020-01-05 [PMID: 32494663] (WB, Human)	WB	Human
Sikorski K, Mehta A et al. A high-throughput pipeline for validation of antibodies. Nat Methods 2018-01-11 [PMID: 30377371] (Human) Details: Antibody validation based on denaturing gel electrophoresis of biotinylated cell lysates (PAGE) followed by mass spectrometry (MS) and antibody array analysis (MAP).		Human
Zhao F, Xu G, Zhou Y et al. MicroRnA-26b Inhibits Hepatitis B Virus Transcription and Replication by Targeting the Host Factor CHORDC1. J. Biol. Chem. 2014-10-23 [PMID: 25342750] (WB, Human)	WB	Human

Array NBP1-78304

• CHORDC1 Antibodies
• CHORDC1 Proteins