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CHORDC1 Antibody [DyLight 550]

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Product Details

Summary
Reactivity Hu, MuSpecies Glossary
Applications WB, ICC/IF, IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
DyLight 550

Order Details

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CHORDC1 Antibody [DyLight 550] Summary

Immunogen
A synthetic peptide made to an internal portion of the human CHORDC1 protein (between residues 100-250) [UniProt Q9UHD1]
Localization
Nucleus. Cytoplasm.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
CHORDC1
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Immunogen affinity purified

Notes



DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for CHORDC1 Antibody [DyLight 550]

  • CHORD domain-containing protein 1
  • CHORD-containing protein 1
  • CHP1CHP-1
  • cysteine and histidine-rich domain (CHORD) containing 1
  • cysteine and histidine-rich domain (CHORD)-containing 1
  • cysteine and histidine-rich domain (CHORD)-containing, zinc-binding protein 1
  • cysteine and histidine-rich domain-containing protein 1
  • FLJ37289
  • Protein morgana

Background

Cysteine and histidine-rich domain containing 1 (CHORDC1; CHP1) is a member of a novel family of highly conserved proteins. These proteins are factors in plant disease resistance, as well as animal development. Mammalian Chp-1 is a novel Hsp90-interacting protein that contains two CHORD domains and one CS domain. CHP-1 binds to the ATPase domain of Hsp90, but this interaction does not utilize ATP and ATPase- coupled conformational change of Hsp90 (PMID: 15642353). High ADP:ATP ratios in cell lysates appears to promote the interaction between CHP1 and Hsp90 (PMID: 19875381). Additionally, CHP-1 has been shown to be 63% homologous to Melusin; a muscle specific protein necessary for heart hypertrophy caused by mechanical burden (PMID12965203).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

FAQs for CHORDC1 Antibody (NBP1-78304R) (0)

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol CHORDC1