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Cdc20 Antibody (AR12) [DyLight 350]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow, ICC/IF, IHC, CyTOF-ready
Clone
AR12
Clonality
Monoclonal
Host
Mouse
Conjugate
DyLight 350

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NBP2-34552AF350
Alexa Fluor 405
NBP2-34552AF405
Alexa Fluor 488
NBP2-34552AF488
Alexa Fluor 532
NBP2-34552AF532
Alexa Fluor 594
NBP2-34552AF594
Alexa Fluor 647
NBP2-34552AF647
Alexa Fluor 700
NBP2-34552AF700
Alexa Fluor 750
NBP2-34552AF750
Allophycocyanin
NBP2-34552APC
Biotin
NBP2-34552B
CoraFluor 1
NBP2-34552CL1
DyLight 405
NBP2-34552V
DyLight 488
NBP2-34552G
DyLight 550
NBP2-34552R
DyLight 594
NBP2-34552DL594
DyLight 650
NBP2-34552C
DyLight 680
NBP2-34552FR
DyLight 755
NBP2-34552IR
FITC
NBP2-34552F
HRP
NBP2-34552H
Janelia Fluor 525
NBP2-34552JF525
Janelia Fluor 549
NBP2-34552JF549
Janelia Fluor 646
NBP2-34552JF646
Janelia Fluor 669
NBP2-34552JF669
PE
NBP2-34552PE
PerCP
NBP2-34552PCP
Unconjugated
NBP2-32954-0.1mg
mFluor Violet 450 SE
NBP2-34552MFV450
mFluor Violet 500 SE
NBP2-34552MFV500
mFluor Violet 610 SE
NBP2-34552MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
NBP2-32954-0.1mg
IHC-Prediluted
NBP2-44406
Azide and BSA Free
NBP2-34552-0.1mg
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Cdc20 Antibody (AR12) [DyLight 350] Summary

Description
This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.
Immunogen
Urea-denatured His6 Cdc20 human recombinant protein (Uniprot: Q12834)
Localization
Cytoplasmic
Isotype
IgG1 Kappa
Clonality
Monoclonal
Host
Mouse
Gene
CDC20
Purity
Protein A or G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
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Applications/Dilutions

Dilutions
  • CyTOF-ready
  • Flow Cytometry
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified

Notes



DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for Cdc20 Antibody (AR12) [DyLight 350]

  • CDC20 cell division cycle 20 homolog (S. cerevisiae)
  • CDC20 cell division cycle 20 homolog
  • Cdc20
  • cell division cycle 20 homolog (S. cerevisiae)
  • cell division cycle protein 20 homolog
  • MGC102824
  • p55CDC
  • p55CDCS. cerevisiae, homolog)

Background

CDC20 is a WD repeat containing cell cycle-regulator that binds to and activates the ubiquitin-ligase activity of the APC/c (anaphase-promoting complex/cyclosome). APC/c ubiquitinating activity is responsible for the degradation of securin and cyclin B that prompts the onset of anaphase and exit from mitosis. CDC20 has also been reported to form a complex with histone deacetylases and can function as a transcriptional repressor involved in cell cycle arrest. As a regulator of APC/c activity, CDC20 plays a key role in the spindle-assembly checkpoint.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Cdc20 Antibody
(AR12) [DyLight 350]
NBP2-34552UV
Cdc20 Antibody (AR12) [DyLight 350]
Species: Hu
Applications: Flow, ICC/IF, IHC, CyTOF-ready

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Product General Protocols

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Video Protocols

ICC/IF Video Protocol

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol CDC20