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CD5L Antibody - BSA Free

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Western Blot: CD5L Antibody [NBP1-76699] - Raji lysate with CD5L antibody at (A) 0.5, (B) 1 and (C) 2 ug/ml.
Western Blot: CD5L Antibody [NBP1-76699] - Raji lysate with CD5L antibody at (A) 0.5, (B) 1 and (C) 2 ug/ml.
Immunohistochemistry-Paraffin: CD5L Antibody [NBP1-76699] - Human lymph node tissue with CD5L antibody at 10 ug/ml.

Product Details

Summary
Reactivity Hu, MuSpecies Glossary
Applications WB, ELISA, IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Format
BSA Free
Concentration
1 mg/ml

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NBP1-76699AF350
Alexa Fluor 405
NBP1-76699AF405
Alexa Fluor 488
NBP1-76699AF488
Alexa Fluor 532
NBP1-76699AF532
Alexa Fluor 594
NBP1-76699AF594
Alexa Fluor 647
NBP1-76699AF647
Alexa Fluor 700
NBP1-76699AF700
Alexa Fluor 750
NBP1-76699AF750
Biotin
NBP1-76699B
DyLight 350
NBP1-76699UV
DyLight 405
NBP1-76699V
DyLight 488
NBP1-76699G
DyLight 550
NBP1-76699R
DyLight 594
NBP1-76699DL594
DyLight 650
NBP1-76699C
DyLight 680
NBP1-76699FR
DyLight 755
NBP1-76699IR
FITC
NBP1-76699F
HRP
NBP1-76699H
Janelia Fluor 549
NBP1-76699JF549
Janelia Fluor 646
NBP1-76699JF646
PerCP
NBP1-76699PCP
mFluor Violet 450 SE
NBP1-76699MFV450
mFluor Violet 500 SE
NBP1-76699MFV500
mFluor Violet 610 SE
NBP1-76699MFV610
View Available Formulations
Catalog# & Formulation Size Price
BSA Free
NBP1-76699-0.025mg
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CD5L Antibody - BSA Free Summary

Immunogen
Antibody was raised against a 13 amino acid synthetic peptide near the carboxy terminus of human AIM. The immunogen is located within amino acids 250 - 300 of AIM. Amino Acid Squence: CDDNWGEKEDQVV
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
CD5L
Purity
Peptide affinity purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • ELISA 1:100-1:2000
  • Immunohistochemistry 10 ug/ml
  • Immunohistochemistry-Paraffin 10 ug/ml
  • Western Blot 0.5-2 ug/ml
Theoretical MW
38 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Control Peptide
CD5L Peptide (NBP1-76699PEP)

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.02% Sodium Azide
Concentration
1 mg/ml
Purity
Peptide affinity purified

Alternate Names for CD5L Antibody - BSA Free

  • AIM
  • API6
  • apoptosis inhibitor 6
  • CD5 antigen-like (scavenger receptor cysteine rich family)
  • CD5 antigen-like
  • CD5 molecule-like
  • CD5L
  • CT-2
  • IgM-associated peptide
  • PRO229
  • Spalpha
  • SP-alpha

Background

Apoptosis inhibitor of macrophages (AIM) is a member of the scavenger receptor cysteine-rich domain superfamily (SRCR-SF) initially identified as an inducible cell surface ligand of CD5. It was shown that AIM functions in the thymus as the inducer of resistance to apoptosis within CD4+/CD8+ thymocytes and as the supporter of the viability of these cells before thymic selection. AIM was also shown to support macrophage survival and enhance their phagocytic function. More recent experiments using recombinant AIM significantly inhibited apoptosis of NKT and T cells obtained from C. parvum-stimulated livers in vitro, suggesting that AIM functions to induce resistance to apoptosis in these cells and supports host defense against inflammation during infection.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol CD5L
Entrez
Uniprot