CD44 Antibody

CD44 represents a family of type I transmembrane glycoproteins expressed on many cell types such as B cells, monocytes, macrophages, and variable subsets of thymocytes and peripheral T cells. CD44 primarily functions as an adhesion molecule. It has been implicated in various processes, such as hematopoiesis, lymphocyte homing, leukocyte activation, tumor metastasis and development. The KM201 monoclonal antibody reacts with an epitope very close to the hyaluronate binding domain on the CD44 molecule. KM201 can inhibit hyaluronate-dependent cell aggregation, prevent lympho-hemopoiesis in both Dexter and Whitlock-Witte Cultures, prevent the earliest intrathymic precursors from homing to the thymus, and costimulate the activation of freshly purified splenic CD4+ T cells.1-6

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 1 confirmed species: Human.

We have publications tested in 1 application: ICC/IF.

Showing Publications 1 - 7 of 7.

Publications using NBP1-84578	Applications	Species
Helen Schneck, Berthold Gierke, Frauke Uppenkamp et al. EpCAM-Independent Enrichment of Circulating Tumor Cells in Metastatic Breast Cancer. PLOS ONE 2015-12-22 [PMID: 26859839] (ICC/IF, Human)	ICC/IF	Human
Ran Ma, Irma Fredriksson, Govindasamy-Muralidharan Karthik et al. Superficial scrapings from breast tumors is a source for biobanking and research purposes. Laboratory Investigation 2014-01-01 [PMID: 24776644] (ICC/IF, Human)	ICC/IF	Human
Baccelli I, Schneeweiss A, Riethdorf S et al. Identification of a population of blood circulating tumor cells from breast cancer patients that initiates metastasis in a xenograft assay. Nat Biotechnol 2013-06-01 [PMID: 23609047]
Petit V, Massonnet G, Maciorowski Z et al. Optimization of tumor xenograft dissociation for the profiling of cell surface markers and nutrient transporters. Lab Invest 2013-05-01 [PMID: 23459372]
Vazquez-Martin A, Oliveras-Ferraros C, Cufi S et al. Metformin regulates breast cancer stem cell ontogeny by transcriptional regulation of the epithelial-mesenchymal transition (EMT) status. Cell Cycle 2010-09-15 [PMID: 20890129]
Twarock S, Rock K, Sarbia M et al. Synthesis of hyaluronan in oesophageal cancer cells is uncoupled from the prostaglandin-cAMP pathway. Br J Pharmacol 2009-05-01 [PMID: 19338584]
Asplund A, Gry Bjorklund M, Sundquist C et al. Expression profiling of microdissected cell populations selected from basal cells in normal epidermis and basal cell carcinoma. Br J Dermatol 2008-03-01 [PMID: 18241271]

Images	Ratings	Applications	Species	Date	Details
Enlarge	4 reviewed by: Verified Customer	IHC-P	Human	04/11/2019	View Summary Application Immunohistochemistry-Paraffin Sample Tested human skin Species Human Lot I113988

Array NBP1-84578

• CD44 Antibodies
• CD44 Antibody Pair
• CD44 ELISA Kits
• CD44 Lysates
• CD44 Protein
• CD44 ELISA
• CD44 Proteins and Enzymes