CD44 Antibody (8E2F3) - BSA Free

CD44, also known as IN, LHRMIC4, CDW44, HCELL, is a cell-surface glycoprotein involved in cell-cell interactions, cell adhesion and migration. It is a receptor for hyaluronic acid (HA) and can also interact with other ligands, such as osteopontin, collagens, and matrix metalloproteinases (MMPs). This protein participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing, hematopoiesis, and tumor metastasis. Transcripts for this gene undergo complex alternative splicing that results in many functionally distinct isoforms, however, the full length nature of some of these variants has not been determined. Alternative splicing is the basis for the structural and functional diversity of this protein, and may be related to tumor metastasis.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 4 confirmed species: Human, Mouse, Rat, Canine.

We have publications tested in 6 applications: FLOW, ICC/IF, IF/IHC, IHC-P, PAGE, WB.

Showing Publications 1 - 10 of 22. Show All 22 Publications. Collapse Publications.

Publications using NBP1-47386	Applications	Species
Zuo Q, Yang Y, Lyu Y, Yang C, Chen C, Salman S, Huang T, Wicks E, Jackson W, Datan E, Qin W, Semenza G Plexin-B3 expression stimulates MET signaling, breast cancer stem cell specification, and lung metastasis. Cell Rep, 2023-02-28;42(3):112164. 2023-02-28 [PMID: 36857181]
Lubanska D, Alrashed S, Mason GT et al. Impairing proliferation of glioblastoma multiforme with CD44+ selective conjugated polymer nanoparticles Scientific reports 2022-07-15 [PMID: 35840697] (PAGE)	PAGE
Saxena N, Bhardwaj G, Jadhav S, et al. Pre-metastatic niche drives breast cancer invasion by modulating MSC homing and CAF differentiation bioRxiv 2021-01-15 (ICC/IF, Human)	ICC/IF	Human
Marzban H, Sasani F Canine Mammary Gland Cancer Stem Cell and its Potential Role in Malignant Biologic Behavior Iranian Journal of Veterinary Medicine 2020-01-01 (WB, Canine)	WB	Canine
Ning Li, Qin Zhu, Yuhua Tian, Kyung Jin Ahn, Xin Wang, Zvi Cramer, Justine Jou, Ian W. Folkert, Pengfei Yu, Stephanie Adams-Tzivelekidis, Priyanka Sehgal, Najia N. Mahmoud, Cary B. Aarons, Robert E. Roses, Andrei Thomas-Tikhonenko, Emma E. Furth, Ben Z. Stanger, Anil Rustgi, Malay Haldar, Bryson W. Katona, Kai Tan, Christopher J. Lengner Mapping and modeling human colorectal carcinoma interactions with the tumor microenvironment Nature Communications 2023-11-30 [PMID: 38036590]
S Vondra, AL Höbler, AI Lackner, J Raffetsede, ZN Mihalic, A Vogel, L Saleh, V Kunihs, P Haslinger, M Wahrmann, H Husslein, R Oberle, J Kargl, S Haider, P Latos, G Schabbauer, M Knöfler, J Ernerudh, J Pollheimer The human placenta shapes the phenotype of decidual macrophages Cell Reports, 2023-01-10;42(1):111977. 2023-01-10 [PMID: 36640334]
Salman S, Meyers DJ, Wicks EE Et al. HIF inhibitor 32-134D eradicates murine hepatocellular carcinoma in combination with anti-PD1 therapy J Clin Invest 2022-05-02 [PMID: 35499076] (FLOW, Mouse) Details: Citation using the Alexa Fluor 488 version of this antibody.	FLOW	Mouse
Li H, Chaitankar V, Zhu J et al. Olfactomedin 4 mediation of prostate stem/progenitor-like cell proliferation and differentiation via MYC Scientific reports 2020-12-14 [PMID: 33318499] (ICC/IF, IHC-P, Human)	ICC/IF, IHC-P	Human
Chen PY, Qin L, Li G et al. Smooth Muscle Cell Reprogramming in Aortic Aneurysms Cell Stem Cell 2020-04-02 [PMID: 32243809] (Mouse)		Mouse
Tsai FJ, Lai MT, Cheng J et al. Novel K6-K14 keratin fusion enhances cancer stemness and aggressiveness in oral squamous cell carcinoma Oncogene 2019-03-13 [PMID: 30867567] (IF/IHC, Mouse)	IF/IHC	Mouse
Hassanzadeh H, Matin MM, Naderi-Meshkin H et al. Using paracrine effects of Ad-MSCs on keratinocyte cultivation and fabrication of epidermal sheets for improving clinical applications Cell Tissue Bank 2018-08-13 [PMID: 30105667] (FLOW, Human)	FLOW	Human
Baek M, kim M, Lim JS et al. Epidermal-specific deletion of TC-PTP promotes UVB-induced epidermal cell survival through the regulation of Flk-1/JNk signaling. Cell Death Dis. 2018-06-28 [PMID: 29955047] (WB, Mouse)	WB	Mouse
Jeong YJ, Oh HK, Park SH, Bong JG. Association between inflammation and cancer stem cell phenotype in breast cancer. Nat Commun. [PMID: 29434947] (IHC-P, Human)	IHC-P	Human
Samanta D, Park Y, Ni X et al. Chemotherapy induces enrichment of CD47+/CD73+/PDL1+ immune evasive triple-negative breast cancer cells Proc. Natl. Acad. Sci. U.S.A. 2018-01-24 [PMID: 29367423] (FLOW, Mouse) Details: This citation used the Alexa Fluor 488 form of this antbody	FLOW	Mouse
Lee HC, Ling QD, Yu WC et al. Drug-resistant colon cancer cells produce high carcinoembryonic antigen and might not be cancer-initiating cells. Drug Des Devel Ther. 2013-01-01 [PMID: 23818760] (IF/IHC, Mouse)	IF/IHC	Mouse
Papakonstantinou E, Klagas I, Karakiulakis G et al. Steroids and beta2-Agonists Regulate Hyaluronan Metabolism in Asthmatic Airway Smooth Muscle Cells Am J Respir Cell Mol Biol 2012-12-01 [PMID: 22865625]
Du W, Wright BM, Li X, Finke J, Rini BI, Zhou M, He H, Lal P, Welford SM. Tumor-derived macrophage migration inhibitory factor promotes an autocrine loop that enhances renal cell carcinoma. Oncogene. 2012-04-30 [PMID: 22543583] (WB, Human)	WB	Human
Asare O The Role of TC-PTP-Mediated Suppression of Autophagy During Skin Carcinogenesis Thesis 2023-01-01
Samanta D, Huang T, Shah R et al. BIRC2 Expression Impairs Anti-Cancer Immunity and Immunotherapy Efficacy Cell Rep [PMID: 32846130] (FLOW, Mouse) Details: Citation using the PE format of this antibody.	FLOW	Mouse
Byun Js, Oh M, Lee S Et Al. The transcription factor PITX1 drives astrocyte differentiation by regulating the SOX9 gene J. Biol. Chem. 2020-08-05 [PMID: 32759168] (IF/IHC, Rat)	IF/IHC	Rat
Scimeca M, Urbano N, Bonfiglio R et al. Breast osteoblast-like cells: a new biomarker for the management of breast cancer. Br. J. Cancer. 2018-10-17 [PMID: 30327566] (IHC-P, Human)	IHC-P	Human
Chefetz I, Alvero AB, Holmberg JC et al. TLR2 enhances ovarian cancer stem cell self-renewal and promotes tumor repair and recurrence. Cell Cycle 2013-02-01 [PMID: 23324344] (WB, IHC-P, FLOW, Human)	WB, IHC-P, FLOW	Human
Show All 22 Publications. Collapse Publications.

Images	Ratings	Applications	Species	Date	Details
Enlarge	5 reviewed by: Corey .	WB	Human	07/12/2013	View Summary Application Western Blot Sample Tested Human Brain Tissue Species Human Lot 130226

Array NBP1-47386

• CD44 Antibodies
• CD44 Antibody Pair
• CD44 ELISA Kits
• CD44 Lysates
• CD44 Protein
• CD44 Proteins and Enzymes
• CD44 ELISA