CD42b/GPIb alpha Antibody (HIP1) [DyLight 488] Summary
Additional Information |
Clone HIP1 was used by HLDA to establish CD designation. |
Immunogen |
Peripheral blood mononuclear cells of a patient suffering with CLL. |
Specificity |
The antibody HIP1 reacts with CD42b (GPIb alpha), a 135-145 kDa membrane glycoprotein expressed on platelets and megakaryocytes. CD42b and CD42c (GPIb beta) are composed in a disulfide linked heterodimer (CD42b/c; 160 kDa); CD42b/c forms a noncovalent complex with CD42a and CD42d. HLDA IV; WS Code P 40 |
Isotype |
IgG1 |
Clonality |
Monoclonal |
Host |
Mouse |
Gene |
GP1BA |
Purity |
Protein A purified |
Innovator's Reward |
Test in a species/application not listed above to receive a full credit towards a future purchase. |
Applications/Dilutions
Dilutions |
- CyTOF-ready
- Flow Cytometry
- Immunohistochemistry
- Immunohistochemistry-Frozen
|
Reactivity Notes
Mouse reactivity reported in scientific literature (PMID: 31467123).
Packaging, Storage & Formulations
Storage |
Store at 4C in the dark. |
Buffer |
50mM Sodium Borate |
Preservative |
0.05% Sodium Azide |
Purity |
Protein A purified |
Notes
DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.
Alternate Names for CD42b/GPIb alpha Antibody (HIP1) [DyLight 488]
Background
CD42b is a platelet activation marker involved in the process of coagulation as an aggregating factor. It interacts with extracellular matrix as well as with adhesion molecules. Its expression and activation seems to be regulated by VEGF and PDGF.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are
guaranteed for 1 year from date of receipt.
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FAQs for CD42b/GPIb alpha Antibody (NB500-511G) (0)
Secondary Antibodies
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