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CCRL2/CRAM-A/B Antibody (152211)

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow, CyTOF-ready
Clone
152211
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated

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CCRL2/CRAM-A/B Antibody (152211) Summary

Immunogen
NS0 mouse myeloma cell line transfected with human CCRL2/CRAM‑A/B
Met1-Val356 (Val180Met)
Accession # NP_001124382
Specificity
Detects human CCRL2/CRAM‑A/B. Stains human HCR-transfected cells but not irrelevant transfectants. It detects both the CRAM-A and CRAM-B isoforms.
Source
N/A
Isotype
IgG2b
Clonality
Monoclonal
Host
Mouse
Gene
CCRL2
Purity Statement
Protein A or G purified from hybridoma culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • CyTOF-ready
  • Flow Cytometry 2.5 ug/10^6 cells
Publications
Read Publications using
MAB2350 in the following applications:

Packaging, Storage & Formulations

Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Buffer
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Preservative
No Preservative
Reconstitution Instructions
Reconstitute at 0.5 mg/mL in sterile PBS.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for CCRL2/CRAM-A/B Antibody (152211)

  • ACKR5
  • C-C chemokine receptor-like 2
  • CCR11
  • CCR6
  • CCRL2
  • CCRL2/CRAM-A/B
  • chemokine (C-C motif) receptor-like 2
  • Chemokine receptor CCR11
  • Chemokine receptor X
  • CKRX
  • CKRXMGC116710
  • CRAM
  • CRAMA
  • CRAM-A
  • CRAMB
  • CRAM-B
  • FLJ55815
  • HCR
  • HCRMGC34104
  • Putative MCP-1 chemokine receptor

Background

HCR, also known as CRAM-A, CRAM-B, CKRX and CCRL2, is a seven-transmembrane G-protein linked receptor that shares homology with other human chemokine receptors. Two isoforms were reported and designated CRAM-A and CRAM-B (1) that differ at their N-termini by the inclusion of an additional 12 amino acids on CRAM-A. HCR/CRAM is expressed at varying levels on a variety of peripheral blood cells including monocytes, neutrophils and T cells (2, 3).
  1. Fan, P. et al. (1998) Biochem. Biophys. Res. Commun. 243:264.
  2. Migeotte, I. et al. (2002) Eur. J. Immunol. 32:494.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for CCRL2/CRAM-A/B Antibody (MAB2350)(3)

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Bioinformatics

Gene Symbol CCRL2
Uniprot