Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70 °C as supplied.
1 month, 2 to 8 °C under sterile conditions after reconstitution.
6 months, -20 to -70 °C under sterile conditions after reconstitution.
Buffer
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Preservative
No Preservative
Reconstitution Instructions
Reconstitute at 0.5 mg/mL in sterile PBS.
Notes
This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.
Alternate Names for CCRL2/CRAM-A/B Antibody (152211)
ACKR5
C-C chemokine receptor-like 2
CCR11
CCR6
CCRL2
CCRL2/CRAM-A/B
chemokine (C-C motif) receptor-like 2
Chemokine receptor CCR11
Chemokine receptor X
CKRX
CKRXMGC116710
CRAM
CRAMA
CRAM-A
CRAMB
CRAM-B
FLJ55815
HCR
HCRMGC34104
Putative MCP-1 chemokine receptor
Background
HCR, also known as CRAM-A, CRAM-B, CKRX and CCRL2, is a seven-transmembrane G-protein linked receptor that shares homology with other human chemokine receptors. Two isoforms were reported and designated CRAM-A and CRAM-B (1) that differ at their N-termini by the inclusion of an additional 12 amino acids on CRAM-A. HCR/CRAM is expressed at varying levels on a variety of peripheral blood cells including monocytes, neutrophils and T cells (2, 3).
Fan, P. et al. (1998) Biochem. Biophys. Res. Commun. 243:264.
Migeotte, I. et al. (2002) Eur. J. Immunol. 32:494.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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