Name: CCL20/MIP-3 alpha Antibody [Unconjugated]
Brand: Novus Biologicals
SKU: AF360
Price: 499 USD

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At	=	A. thaliana	SyHa	=	Golden Syrian Hamster
All	=	All Species	Ha	=	Hamster
An	=	Animal	Hu	=	Human
ArHa	=	Armenian Hamster	I	=	Insect
Av	=	Avian	Ll	=	Llama
Bb	=	Baboon	Ma	=	Mammal
Ba	=	Bacteria	Mk	=	Monkey
Bv	=	Bovine	Mu	=	Mouse
Ca	=	Canine	Multi	=	Multi-species
Ce	=	C. Elegans	NA	=	Non-species specific
Ch	=	Chicken	Or	=	Orangutan
ChHa	=	Chinese Hamster	Pl	=	Plant
Cm	=	Cynomolgus Monkey	Pm	=	Primate
Do	=	Donkey	Po	=	Porcine
Dr	=	Drosophilia	Rb	=	Rabbit
Ec	=	E. Coli	Rt	=	Rat
Eq	=	Equine	RM	=	Rhesus Macaque
Fe	=	Feline	Sh	=	Sheep
Ft	=	Ferret	Vb	=	Vertebrate
Fi	=	Fish	Vi	=	Virus
Fu	=	Fungi	Xp	=	Xenopus
Ge	=	Gerbil	Ye	=	Yeast
GP	=	Guinea Pig	Ze	=	Zebrafish
Gt	=	Goat

Reactivity	HuSpecies Glossary
Applications	IHC, B/N, ICC/IF
Clonality	Polyclonal
Host	Goat
Conjugate	Unconjugated
Concentration	LYOPH

Conjugate	Catalog #	Availability	Size	Price
Biotin	BAF360

Immunogen	E. coli-derived recombinant human CCL20/MIP-3 alpha Ala27-Met96 (Asn95Asp) Accession # P78556
Specificity	Detects human CCL20/MIP-3 alpha in direct ELISAs.
Source	N/A
Isotype	IgG
Clonality	Polyclonal
Host	Goat
Gene	CCL20
Purity Statement	Antigen Affinity-purified
Endotoxin Note	<0.10 EU per 1 μg of the antibody by the LAL method.
Innovator's Reward	Test in a species/application not listed above to receive a full credit towards a future purchase. Learn about the Innovator's Reward

Storage	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Buffer	Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Preservative	No Preservative
Concentration	LYOPH
Reconstitution Instructions	Reconstitute at 0.2 mg/mL in sterile PBS.

CCL20/MIP-3 alpha Antibody [Unconjugated]

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CCL20/MIP-3 alpha Antibody [Unconjugated] Summary

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Publications for CCL20/MIP-3 alpha Antibody (AF360)(23)

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Bioinformatics

Publications using AF360	Applications	Species
F Parween, SP Singh, HH Zhang, N Kathuria, FA Otaizo-Car, A Shamsaddin, PJ Gardina, S Ganesan, J Kabat, HA Lorenzi, TG Myers, JM Farber Chemokine positioning determines mutually exclusive roles for their receptors in extravasation of pathogenic human T cells bioRxiv : the preprint server for biology, 2023-02-13;0(0):. 2023-02-13 [PMID: 36789428] (ICC, Human)	ICC	Human
KR Brink, MG Hunt, AM Mu, K Groszman, KV Hoang, KP Lorch, BH Pogostin, JS Gunn, JJ Tabor An E. coli display method for characterization of peptide-sensor kinase interactions Nature Chemical Biology, 2022-12-08;0(0):. 2022-12-08 [PMID: 36482094] (Human)		Human
Wang W, Lin Y, Zhang F et al. Single cell transcriptomic analysis of human amnion identifies cell-specific signatures associated with membrane rupture and parturition Cell Biosci. 5/18/2022 [PMID: 35585644]
Louis Boafo Kwantwi, Shujing Wang, Wenjun Zhang, Weidong Peng, Zeyu Cai, Youjing Sheng et al. Tumor-associated neutrophils activated by tumor-derived CCL20 (C-C motif chemokine ligand 20) promote T cell immunosuppression via programmed death-ligand 1 (PD-L1) in breast cancer Bioengineered 9/14/2021 [PMID: 34519637]
JL Booth, ES Duggan, VI Patel, W Wu, DM Burian, DC Hutchings, VL White, KM Coggeshall, MG Dozmorov, JP Metcalf Gene expression profiling of primary human type I alveolar epithelial cells exposed to Bacillus anthracis spores reveals induction of neutrophil and monocyte chemokines Microb. Pathog., 2018-04-25;0(0):. 2018-04-25 [PMID: 29704667] (Neutralization, Human)	Neutralization	Human
XP Zhang, ZJ Hu, AH Meng, GC Duan, QT Zhao, J Yang Role of CCL20/CCR6 and the ERK signaling pathway in lung adenocarcinoma Oncol Lett, 2017-10-23;14(6):8183-8189. 2017-10-23 [PMID: 29250193] (IHC-P, Human)	IHC-P	Human
Rump L, Mattey D, Kehoe O, Middleton J An initial investigation into endothelial CC chemokine expression in the human rheumatoid synovium. Cytokine, 2017-09-01;97(0):133-140. 2017-09-01 [PMID: 28648867] (IHC-Fr, Human)	IHC-Fr	Human
X Ye, R Wang, R Bhattachar, D Boulbes, F Fan, L Xia, H Adoni, NJ Ajami, MC Wong, DP Smith, JF Petrosino, S Venable, W Qiao, V Baladanday, DM Maru, LM Ellis Fusobacterium nucleatum subspecies animalis influences pro-inflammatory cytokine expression and monocyte activation in human colorectal tumors Cancer Prev Res (Phila), 2017-05-08;0(0):. 2017-05-08 [PMID: 28483840] (Neutralization, Human)	Neutralization	Human
Brand O, Somanath S, Moermans C, Yanagisawa H, Hashimoto M, Cambier S, Markovics J, Bondesson A, Hill A, Jablons D, Wolters P, Lou J, Marks J, Baron J, Nishimura S Transforming Growth Factor-beta and Interleukin-1beta Signaling Pathways Converge on the Chemokine CCL20 Promoter. J Biol Chem, 2015-04-27;290(23):14717-28. 2015-04-27 [PMID: 25918170] (IHC-P, Human)	IHC-P	Human
Yu , Qing, Lou , Xiang-mi, He , Yan Preferential recruitment of Th17 cells to cervical cancer via CCR6-CCL20 pathway. PLoS ONE, 2015-03-13;10(3):e0120855. 2015-03-13 [PMID: 25768730] (Bioassay, Human)	Bioassay	Human
Hashikawa K, Yasumoto S, Nakashima K, Arakawa F, Kiyasu J, Kimura Y, Saruta H, Nakama T, Yasuda K, Tashiro K, Kuhara S, Hashimoto T, Ohshima K Microarray analysis of gene expression by microdissected epidermis and dermis in mycosis fungoides and adult T-cell leukemia/lymphoma. Int J Oncol, 2014-06-26;45(3):1200-8. 2014-06-26 [PMID: 24970722] (IHC-P, Human)	IHC-P	Human
Nandi , Bisweswa, Pai , Christin, Huang , Qin, Prabhala , Rao H, Munshi , Nikhil C, Gold , Jason S CCR6, the sole receptor for the chemokine CCL20, promotes spontaneous intestinal tumorigenesis. PLoS ONE, 2014-05-27;9(5):e97566. 2014-05-27 [PMID: 24866282] (IHC-P, Mouse)	IHC-P	Mouse
Chen J, Wu M, Kuo S, Liao F IL-22 negatively regulates Helicobacter pylori-induced CCL20 expression in gastric epithelial cells. PLoS ONE, 2014-05-13;9(5):e97350. 2014-05-13 [PMID: 24824519] (IHC, Human)	IHC	Human
Vincent-Bugnas S, Vitale S, Mouline C, Khaali W, Charbit Y, Mahler P, Precheur I, Hofman P, Maryanski J, Doglio A EBV infection is common in gingival epithelial cells of the periodontium and worsens during chronic periodontitis. PLoS ONE, 2013-12-19;8(12):e80336. 2013-12-19 [PMID: 24367478] (ICC, Human)	ICC	Human
BENJAMIN VICINUS, CLAUDIA RUBIE, NATHALIE STEGMAIER, VILMA OLIVEIRA FRICK, KATHRIN KÖLSCH, ANNE KAUFFELS et al. miR-21 and its target gene CCL20 are both highly overexpressed in the microenvironment of colorectal tumors: Significance of their regulation Oncology Reports 9/1/2013 [PMID: 23817679]
Sperling T, Oldak M, Walch-Ruckheim B, Wickenhauser C, Doorbar J, Pfister H, Malejczyk M, Majewski S, Keates AC, Smola S Human Papillomavirus Type 8 Interferes with a Novel C/EBPÃŽÂ²-Mediated Mechanism of Keratinocyte CCL20 Chemokine Expression and Langerhans Cell Migration. PLoS Pathog., 2012-07-26;8(7):e1002833. 7/26/2012 [PMID: 22911498]
Shan M, Cheng HF, Song LZ Lung myeloid dendritic cells coordinately induce TH1 and TH17 responses in human emphysema. Sci Transl Med, 2009-10-28;1(4):4ra10. 2009-10-28 [PMID: 20368170] (ICC, IHC-Fr, Human)	ICC, IHC-Fr	Human
Yuangang Liu, James P. Lagowski, Shangpu Gao, James H. Raymond, Clifton R. White, Molly F. Kulesz-Martin Regulation of the Psoriatic Chemokine CCL20 by E3 Ligases Trim32 and Piasy in Keratinocytes Journal of Investigative Dermatology 5/1/2010 [PMID: 20054338]
Chang KP, Hao SP, Chang JH, Wu CC, Tsang NM, Lee YS, Hsu CL, Ueng SH, Liu SC, Liu YL, Wei PC, Liang Y, Chang YS, Yu JS Macrophage inflammatory protein-3alpha is a novel serum marker for nasopharyngeal carcinoma detection and prediction of treatment outcomes. Clin. Cancer Res., 2008-11-01;14(21):6979-87. 2008-11-01 [PMID: 18980993] (IHC, Human)	IHC	Human
Lee SK, Pi SH, Kim SH, Min KS, Lee HJ, Chang HS, Kang KH, Kim HR, Shin HI, Lee SK, Kim EC Substance P regulates macrophage inflammatory protein 3alpha/chemokine C-C ligand 20 (CCL20) with heme oxygenase-1 in human periodontal ligament cells. Clin. Exp. Immunol., 2007-10-09;150(3):567-75. 2007-10-09 [PMID: 17924972] (ELISA Development, Human)	ELISA Development	Human
Facco M, Baesso I, Miorin M, Bortoli M, Cabrelle A, Boscaro E, Gurrieri C, Trentin L, Zambello R, Calabrese F, Cassatella MA, Semenzato G, Agostini C Expression and role of CCR6/CCL20 chemokine axis in pulmonary sarcoidosis. J. Leukoc. Biol., 2007-07-05;82(4):946-55. 2007-07-05 [PMID: 17615381] (ELISA Development, IHC-Fr, IHC-P, Human)	ELISA Development, IHC-Fr, IHC-P	Human
Marchal-Somme J, Uzunhan Y, Marchand-Adam S, Valeyre D, Soumelis V, Crestani B, Soler P Cutting edge: nonproliferating mature immune cells form a novel type of organized lymphoid structure in idiopathic pulmonary fibrosis. J. Immunol., 2006-05-15;176(10):5735-9. 2006-05-15 [PMID: 16670278] (IHC-Fr, Human)	IHC-Fr	Human
Vanbervliet B, Homey B, Durand I, Massacrier C, Ait-Yahia S, de Bouteiller O, Vicari A, Caux C Sequential involvement of CCR2 and CCR6 ligands for immature dendritic cell recruitment: possible role at inflamed epithelial surfaces. Eur J Immunol, 2002-01-01;32(1):231-42. 2002-01-01 [PMID: 11782014] (IHC-Fr, Human)	IHC-Fr	Human
Show All 23 Publications. Collapse Publications.

Catalog# & Formulation	Size	Price
Carrier Free AF360-SP

Gene Symbol	CCL20
Uniprot	P78556()