c-Maf Antibody (883926) [Unconjugated]

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

c-Maf is an approximately 40 kDa transcriptional regulator that contains one bZIP domain. It can associate into homodimers and heterodimers with other basic leucine zipper transcription factors. c-Maf plays an important role in fetal erythropoiesis, lens development, mechanosensory neuron development, and the differentiation of chondrocytes and osteoblasts. In the pancreas, c-Maf promotes the transcription of glucagon in alpha cells and insulin in beta cells. In immune cells, it controls Th17 and Treg differentiation by regulating the transcription of IL-4, IL-12 p35, IL-21, IL-22, and GM-CSF. Human c-Maf shares 97% amino acid sequence identity with mouse and rat c-Maf. Alternative splicing of human c-Maf generates a long isoform with a 30 aa substitution for the C-terminal methionine.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Images	Ratings	Applications	Species	Date	Details
Enlarge	3 reviewed by: Natalie Erdmann	Immunocytochemistry/Immunofluorescence	Human	10/24/2016	View Summary Application Immunocytochemistry/Immunofluorescence Sample Tested RPMI-8226 Species Human Lot CIHK051508A Comments Comments Immersion-fixed cells; permeabilized Triton X-100 5 min; blocked 1 hour 10% donkey serum; 1/30 O/N @4oC; Donkey F(ab’)2 anti-mouse IgG (H+L) Alexa Fluor 647 Abcam #ab150103 1 hour at rt; Zeiss AxioImager Cy5 filter cube 500 ms exposure

Array MAB8227

• c-Maf Antibodies
• c-Maf ELISA Kits
• c-Maf Proteins