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BMP-2 Antibody [DyLight 550]

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Product Details

Summary
Reactivity Hu, Mu, Rt, CaSpecies Glossary
Applications WB, ICC/IF, IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
DyLight 550

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NBP1-19751AF350
Alexa Fluor 405
NBP1-19751AF405
Alexa Fluor 488
NBP1-19751AF488
Alexa Fluor 532
NBP1-19751AF532
Alexa Fluor 594
NBP1-19751AF594
Alexa Fluor 647
NBP1-19751AF647
Alexa Fluor 700
NBP1-19751AF700
Alexa Fluor 750
NBP1-19751AF750
Allophycocyanin
NBP1-19751APC
Biotin
NBP1-19751B
DyLight 350
NBP1-19751UV
DyLight 405
NBP1-19751V
DyLight 488
NBP1-19751G
DyLight 594
NBP1-19751DL594
DyLight 650
NBP1-19751C
DyLight 680
NBP1-19751FR
DyLight 755
NBP1-19751IR
FITC
NBP1-19751F
HRP
NBP1-19751H
Janelia Fluor 549
NBP1-19751JF549
Janelia Fluor 646
NBP1-19751JF646
PE
NBP1-19751PE
PerCP
NBP1-19751PCP
Unconjugated
NBP1-19751
mFluor Violet 450 SE
NBP1-19751MFV450
mFluor Violet 500 SE
NBP1-19751MFV500
mFluor Violet 610 SE
NBP1-19751MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
NBP1-19751
BSA Free
NBP1-19751
BSA Free
NBP1-19751SS
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BMP-2 Antibody [DyLight 550] Summary

Immunogen
A synthetic peptide made to an internal region of human BMP2 (within residues 250-350) [Swiss-Prot# P12643]
Localization
Secreted
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
BMP2
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

Use in Canine reported in scientific literature (PMID:34311726)

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Immunogen affinity purified

Notes



DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for BMP-2 Antibody [DyLight 550]

  • BDA2
  • BMP2
  • BMP-2
  • BMP-2A
  • BMP2ABone morphogenetic protein 2A
  • bone morphogenetic protein 2
  • SSFSC

Background

Bone morphogenic protein 2 is required for effective healing of fractures in bone. It is necessary for the expression of transcription factors that regulate osteogenesis and differentiation of progenitor cells into mature osteoblasts. Embryologically, BMP2 is important in mesenchymal maturation to fetal valves. The same mechanism of maturation is also utilized by tumor molecular machinery once mesenchymal stem cells are recruited to tumor microenvironments, leading to many recent attempts to generate BMP inhibitors in the treatment of ovarian and colon cancer. The activity of BMP2 is antagonized by the activity of Bambi and Crim1. BMP2 is an interesting target for distinguishing the mechanism by which normal and necessary maturation processes are mutated in tumorigenesis.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Species: Mu
Applications: BA

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Product General Protocols

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Video Protocols

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ICC/IF Video Protocol

FAQs for BMP-2 Antibody (NBP1-19751R). (Showing 1 - 1 of 1 FAQ).

  1. I am interested in Bone Morphogenic Protein 2 (BMP-2) for clinical trial in humans. I am using this protein in stem cells culture for future use in humans. Do you have BMP-2 in pharma grade that I can use for humans?
    • Our antibodies are for research purposes only unfortunately. I am sorry we cannot be of further help.

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Bioinformatics

Gene Symbol BMP2