Use in Canine reported in scientific literature (PMID:34311726)
Packaging, Storage & Formulations
Storage
Store at 4C in the dark.
Buffer
PBS
Preservative
0.05% Sodium Azide
Purity
Immunogen affinity purified
Alternate Names for BMP-2 Antibody [Biotin]
BDA2
BMP2
BMP-2
BMP-2A
BMP2ABone morphogenetic protein 2A
bone morphogenetic protein 2
SSFSC
Background
Bone morphogenic protein 2 is required for effective healing of fractures in bone. It is necessary for the expression of transcription factors that regulate osteogenesis and differentiation of progenitor cells into mature osteoblasts. Embryologically, BMP2 is important in mesenchymal maturation to fetal valves. The same mechanism of maturation is also utilized by tumor molecular machinery once mesenchymal stem cells are recruited to tumor microenvironments, leading to many recent attempts to generate BMP inhibitors in the treatment of ovarian and colon cancer. The activity of BMP2 is antagonized by the activity of Bambi and Crim1. BMP2 is an interesting target for distinguishing the mechanism by which normal and necessary maturation processes are mutated in tumorigenesis.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
FAQs for BMP-2 Antibody (NBP1-19751B). (Showing 1 - 1 of 1 FAQ).
I am interested in Bone Morphogenic Protein 2 (BMP-2) for clinical trial in humans. I am using this protein in stem cells culture for future use in humans. Do you have BMP-2 in pharma grade that I can use for humans?
Our antibodies are for research purposes only unfortunately. I am sorry we cannot be of further help.
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