BMP-2 Products

Description

Bone morphogenic proteins (BMPs) are members of the TGFbeta superfamily. BMPs are involved in the induction of cartilage and bone formation. In vivo studies have shown that BMP-2 (also designated BMP-2A) and BMP-3 can independently induce cartilage formation. Smad3 association with the TGFbeta receptor complex and Smad1 translocation to the nucleus are observed after the addition of BMP-4 (also designated BMP-2B), suggesting that BMP-4 may play a role in activation of the Smad pathway. BMP-5, BMP-6 and BMP-7 all share high sequence homology with BMP-2, indicating that they each may be able to induce cartilage formation. BMP-8 (also designated OP-2) is thought to be involved in early development, as detectable expression has not been found in adult organs.

Bioinformatics

Entrez	12156 Mouse 29373 Rat 650 Human
Uniprot	AAI48690.1 Human NM_001200 Human NP_001191 Human P12643 Human P21274 Mouse
Product By Gene ID	650
Alternate Names	BMP-2 BMP-2A BMP2ABone morphogenetic protein 2A bone morphogenetic protein 2

Research Areas for BMP-2

Find related products by research area and learn more about each of the different research areas below.

Cytokine Research
Embryonic Stem Cell Markers
Immunology
Neuronal Cell Markers
Neuronal Stem Cell Markers
Stem Cell Markers
Stem Cell Signaling Pathway