B7-H2/ICOSLG Antibody (987614) [HRP] Summary
Immunogen |
Mouse myeloma cell line NS0-derived recombinant mouse B7-H2 Met1-Lys279 Accession # Q9JHJ8 |
Specificity |
Detects mouse B7-H2 in direct ELISAs.
|
Isotype |
IgG1 |
Clonality |
Monoclonal |
Host |
Rat |
Innovator's Reward |
Test in a species/application not listed above to receive a full credit towards a future purchase. |
Applications/Dilutions
Dilutions |
- Blockade of Receptor-ligand Interaction
- CyTOF-ready
- Flow Cytometry
|
Application Notes |
Optimal dilution of this antibody should be experimentally determined. |
Packaging, Storage & Formulations
Storage |
Store at 4C in the dark. |
Buffer |
PBS |
Preservative |
No Preservative |
Alternate Names for B7-H2/ICOSLG Antibody (987614) [HRP]
Background
B7-RP1 is a 40 kD protein, also known as ICOS ligand, B7-H2, and B7h. It has recently been clustered as CD275. It is a member of the immunoglobulin receptor superfamily expressed on splenic B cells, dendritic cells and macrophages. The expression of this antigen is increased by TNF- alpha stimulation and is highly upregulated by local inflammation. B7RP1 binds to ICOS and co-stimulates T cell and B cell responses. Two isoforms of this protein have been reported to occur as a result of alternative splicing. These isoforms show differential tissue distribution.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are
guaranteed for 1 year from date of receipt.
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FAQs for B7-H2/ICOSLG Antibody (FAB1582H) (0)
Secondary Antibodies
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Isotype Controls
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