Species: Hu
Applications: Flow, B/N, CyTOF-ready
Host: Mouse Monoclonal
Species: Hu
Applications: WB, Flow, CyTOF-ready
Host: Goat Polyclonal
Species: Mu
Applications: Flow, B/N, CyTOF-ready
Host: Rat Monoclonal
Species: Hu
Applications: ELISA
Host: Mouse Monoclonal
Species: Hu
Applications: ELISA
Species: Mu
Applications: ELISA
Species: Hu
Applications: WB
Species: Hu
Applications: Bioactivity
Species: Hu
Applications: Bioactivity
Species: Hu
Applications: Bioactivity
Description
B7-RP1 is a 40 kD protein, also known as ICOS ligand, B7-H2, and B7h. It has recently been clustered as CD275. It is a member of the immunoglobulin receptor superfamily expressed on splenic B cells, dendritic cells and macrophages. The expression of this antigen is increased by TNF- alpha stimulation and is highly upregulated by local inflammation. B7RP1 binds to ICOS and co-stimulates T cell and B cell responses. Two isoforms of this protein have been reported to occur as a result of alternative splicing. These isoforms show differential tissue distribution.
Bioinformatics
| Entrez |
Human
Mouse
|
| Uniprot |
Human
Human
Human
|
| Product By Gene ID |
23308 |
| Alternate Names |
- B7H2B7 homolog 2
- B7-H2B7-related protein 1
- B7RP1B7-like protein Gl50
- B7RP-1LICOS
- CD275 antigen
- CD275
- GL50transmembrane protein B7-H2 ICOS ligand
- ICOSL
- ICOS-L
- inducible T-cell co-stimulator ligand
- KIAA0653ICOS ligand
|
Research Areas for B7-H2/ICOSLG
Find related products by research area and learn more about each of the different research areas below.
Cell Cycle and Replication
![Flow Cytometry B7-H2/ICOSLG Antibody (136726) [Unconjugated]](http://images.novusbio.com/fullsize2/B7-H2_MAB165_Flow_Cytometry_8343.jpg)
![Western Blot B7-H2/ICOSLG Antibody [Unconjugated]](http://images.novusbio.com/fullsize2/B7H2_AF165_Western_Blot_20282.jpg)
![Blockade of Receptor-ligand Interaction B7-H2/ICOSLG Antibody (987602) [Unconjugated]](http://images.novusbio.com/fullsize2/B7H2_MAB10083_Block_Neutralize_23355.jpg)
![Sandwich ELISA B7-H2/ICOSLG Antibody Pair [HRP]](http://images.novusbio.com/fullsize/B7-H2-ICOSLG-Antibody-Pair-[HRP]-Sandwich-ELISA-NBP2-79653-img0001.jpg)
![N/A B7-H2/ICOSLG [Biotin]](http://images.novusbio.com/fullsize2/B7H2_DY16505_ELISA_2569.jpg)
![N/A B7-H2/ICOSLG [Biotin]](http://images.novusbio.com/fullsize2/dy10083-05_mouse-b7-h2-duoset-elisa-5-plate-19202295833.png)
![Bioactivity B7-H2/ICOSLG [Unconjugated]](http://images.novusbio.com/fullsize2/B7H2_165B7_2309.jpg)
![Bioactivity B7-H2/ICOSLG [Unconjugated]](http://images.novusbio.com/fullsize2/B7H2_8206B7_1012.jpg)
![Binding Activity B7-H2/ICOSLG [Biotin]](http://images.novusbio.com/fullsize/protein/avi165_recombinant-human-b7-h2-fc-chimera-avi-tag-protein-cf-binding-activity-1852020134859.jpg)
![Neutralization B7-H2/ICOSLG Antibody (136726) [Unconjugated]](http://images.novusbio.com/fullsize2/B7-H2_MAB165_Block_Neutralize_9035.jpg)
![Flow Cytometry B7-H2/ICOSLG Antibody [Unconjugated]](http://images.novusbio.com/fullsize2/B7-H2_AF165_Flow_Cytometry_8160.jpg)
![Flow Cytometry B7-H2/ICOSLG Antibody (987602) [Unconjugated]](http://images.novusbio.com/fullsize2/B7H2_MAB10083_Flow_Cytometry_23035.jpg)
![Neutralization B7-H2/ICOSLG Antibody (987602) [Unconjugated]](http://images.novusbio.com/fullsize2/B7H2_MAB10083_Block_Neutralize_23088.jpg)
![SDS-PAGE B7-H2/ICOSLG [Unconjugated]](http://images.novusbio.com/fullsize2/B7H2_8206B7_1340.jpg)
![N/A B7-H2/ICOSLG [Biotin]](http://images.novusbio.com/fullsize/protein/avi165_recombinant-human-b7-h2-fc-chimera-avi-tag-protein-cf-152020133948.jpg)