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ARC/NOL3 Antibody - BSA Free

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Western Blot: ARC/NOL3 Antibody [NBP2-41753] - ARC in HeLa (H), KB (K), and A549 (A) whole cell lysates with anti-ARC (CT) at a 1:1000 dilution.
Western Blot: ARC/NOL3 Antibody [NBP2-41753] - ARC in HeLa (H), KB (K), and A549 (A) whole cell lysates with anti-ARC (CT) at a 1:1000 dilution.
Immunohistochemistry: ARC/NOL3 Antibody [NBP2-41753] - Human heart tissue at 5 ug/mL
Immunohistochemistry-Paraffin: ARC/NOL3 Antibody [NBP2-41753] - Human skeletal muscle with ARC/NOL3 antibody at 5 ug/mL.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ELISA, IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Format
BSA Free
Concentration
1 mg/ml

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NBP2-41753AF350
Alexa Fluor 405
NBP2-41753AF405
Alexa Fluor 488
NBP2-41753AF488
Alexa Fluor 532
NBP2-41753AF532
Alexa Fluor 594
NBP2-41753AF594
Alexa Fluor 647
NBP2-41753AF647
Alexa Fluor 700
NBP2-41753AF700
Alexa Fluor 750
NBP2-41753AF750
Biotin
NBP2-41753B
DyLight 350
NBP2-41753UV
DyLight 405
NBP2-41753V
DyLight 488
NBP2-41753G
DyLight 550
NBP2-41753R
DyLight 594
NBP2-41753DL594
DyLight 650
NBP2-41753C
DyLight 680
NBP2-41753FR
DyLight 755
NBP2-41753IR
FITC
NBP2-41753F
HRP
NBP2-41753H
Janelia Fluor 549
NBP2-41753JF549
Janelia Fluor 646
NBP2-41753JF646
PerCP
NBP2-41753PCP
mFluor Violet 450 SE
NBP2-41753MFV450
mFluor Violet 500 SE
NBP2-41753MFV500
mFluor Violet 610 SE
NBP2-41753MFV610
View Available Formulations
Catalog# & Formulation Size Price
BSA Free
NBP2-41753-0.025mg
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ARC/NOL3 Antibody - BSA Free Summary

Immunogen
Antibody was raised against an 18 amino acid peptide near the carboxy terminus of human ARC. The immunogen is located within the last 50 amino acids of ARC. Amino Acid Squence: PDPEPEPDFEERDESEDS
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
NOL3
Purity
Peptide affinity purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • ELISA
  • Immunohistochemistry 5 ug/ml
  • Immunohistochemistry-Paraffin 5 ug/ml
  • Western Blot 1-2 ug/ml
Theoretical MW
25 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Publications
Read Publication using
NBP2-41753 in the following applications:

  • WB
    1 publication

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.02% Sodium Azide
Concentration
1 mg/ml
Purity
Peptide affinity purified

Alternate Names for ARC/NOL3 Antibody - BSA Free

  • Apoptosis repressor with CARD
  • ARC
  • ARCFLJ35304
  • CARD2
  • Muscle-enriched cytoplasmic protein
  • MYC
  • MYP
  • NOL3
  • NOP30
  • NOPnucleolar protein 3
  • nucleolar protein 3 (apoptosis repressor with CARD domain)
  • Nucleolar protein of 30 kDa

Background

Apoptosis is regulated by death domain (DD) and/or caspase recruitment domain (CARD) containing molecules and a caspase family of proteases. CARD domain containing cell death regulators include RAIDD, Apaf-1, caspase-9, and caspase-2. A novel CARD domain containing protein was recently identified and designated ARC for apoptosis repressor with CARD. ARC interacts with caspase-2 and -8 and inhibits enzymatic activity of caspase-8. ARC suppresses apoptosis induced by cell death adapters FADD and TRADD and by cell death receptors Fas, TNFR-1 and DR3. The messenger RNA of ARC is primarily expressed in skeletal muscle and cardiac tissue.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for ARC/NOL3 Antibody (NBP2-41753)(1)

We have publications tested in 1 confirmed species: Human.

We have publications tested in 1 application: WB.


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Bioinformatics

Gene Symbol NOL3
Uniprot