Apolipoprotein H/ApoH Antibody (517038) [Unconjugated]

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Apolipoprotein H (ApoH also known as beta 2-Glycoprotein 1/ beta 2-GPI) is a 50 kDa secreted monomeric glycoprotein member of the complement control superfamily of molecules. It is produced by hepatocytes and is bound to HDL particles. Circulating ApoH blocks the intrinsic clotting pathway and binds to exposed phospholipids on apoptotic cells. Mature human ApoH contains four Sushi repeats (aa 21‑260) and one C-terminal kringle domain (aa 261‑345) that binds heparin and phospholipids. At least two isoforms exist. One shows a 31 aa substitution for aa 140‑345, while a second represents a bioactive plasmin cleavage product that removes the C-terminal nine amino acids. Mature human ApoH shares 76% aa identity with mouse ApoH.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 1 confirmed species: Human.

We have publications tested in 1 application: Western Blot.

Showing Publication 1 - 1 of 1.

Publication using MAB5087	Applications	Species
Macheboeuf P, Buffalo C, Fu CY, Zinkernagel AS, Cole JN, Johnson JE, Nizet V, Ghosh P Streptococcal M1 protein constructs a pathological host fibrinogen network. Nature, 2011-04-07;472(7341):64-8. 2011-04-07 [PMID: 21475196] (Western Blot, Human)	Western Blot	Human

Array MAB5087

• Apolipoprotein H/ApoH Antibodies
• Apolipoprotein H/ApoH Antibody Pair
• Apolipoprotein H/ApoH ELISA Kits
• Apolipoprotein H/ApoH Lysate
• Apolipoprotein H/ApoH Proteins
• Apolipoprotein H/ApoH Proteins and Enzymes