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Angiopoietin-2 Antibody (OTI3H7) [Janelia Fluor® 549]

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Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications IHC
Clone
OTI3H7
Clonality
Monoclonal
Host
Mouse
Conjugate
Janelia Fluor 549

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NBP2-70173AF350
Alexa Fluor 405
NBP2-70173AF405
Alexa Fluor 488
NBP2-70173AF488
Alexa Fluor 532
NBP2-70173AF532
Alexa Fluor 594
NBP2-70173AF594
Alexa Fluor 647
NBP2-70173AF647
Alexa Fluor 700
NBP2-70173AF700
Alexa Fluor 750
NBP2-70173AF750
Allophycocyanin
NBP2-70173APC
Biotin
NBP2-70173B
CoraFluor 1
NBP2-70173CL1
DyLight 350
NBP2-70173UV
DyLight 405
NBP2-70173V
DyLight 488
NBP2-70173G
DyLight 550
NBP2-70173R
DyLight 594
NBP2-70173DL594
DyLight 650
NBP2-70173C
DyLight 680
NBP2-70173FR
DyLight 755
NBP2-70173IR
FITC
NBP2-70173F
HRP
NBP2-70173H
Janelia Fluor 525
NBP2-70173JF525
Janelia Fluor 585
NBP2-70173JF585
Janelia Fluor 635
NBP2-70173JF635
Janelia Fluor 646
NBP2-70173JF646
Janelia Fluor 669
NBP2-70173JF669
PE
NBP2-70173PE
PerCP
NBP2-70173PCP
Unconjugated
NBP2-46520
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
NBP2-46520
Azide and BSA Free
NBP2-70173
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Angiopoietin-2 Antibody (OTI3H7) [Janelia Fluor® 549] Summary

Immunogen
Recombinant protein fragment corresponding to amino acids 19-496 of human Angiopoietin-2 (NP_001138) produced in E.coli.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
ANGPT2
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

Please note that this antibody is reactive to Mouse and derived from the same host, Mouse. Mouse-On-Mouse blocking reagent may be needed for IHC and ICC experiments to reduce high background signal. You can find these reagents under catalog numbers PK-2200-NB and MP-2400-NB. Please contact Technical Support if you have any questions.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Immunogen affinity purified

Notes

Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for Angiopoietin-2 Antibody (OTI3H7) [Janelia Fluor® 549]

  • AGPT2
  • ANG2
  • ANG-2
  • angiopoietin 2
  • Angiopoietin-2
  • angiopoietin-2a
  • angiopoietin-2B
  • angiopoitin 2
  • ANGPT2
  • Tie2-ligand

Background

Angiopoietin 1 and Angiopoietin 2 are important for development of the endothelium, by regulating tyrosine phosphorylation of the membrane receptor Tie 2/Tek. Angiopoietin 2 is only 60% homologous with Angiopoietin 1. Angiopoietin 1 binding to Tie 2/Tek causes phosphorylation of the receptor. Angiopoietin 2 competes for this binding, and thus blocks receptor phosphorylation. Angiopoietin 2 expression occurs at sites of vascular remodeling: dorsal aorta and major aortic branches, ovary, placenta and uterus.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Angiopoietin-2
Antibody (OTI3H7) [Ja ...
NBP2-70173JF549
Angiopoietin-2 Antibody (OTI3H7) [Janelia Fluor® 549]
Species: Hu, Mu, Rt
Applications: IHC

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Bioinformatics

Gene Symbol ANGPT2