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AGER Antibody (CL10591)

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Staining of human prostate shows no positivity in glandular cells as expected.
Staining of human prostate shows no positivity in glandular cells as expected.
Staining of human lung shows strong membranous positivity in pneumocytes.
Staining of human kidney shows no positivity in cells in tubules as expected.
Orthogonal Strategies: Analysis in human lung and prostate tissues using NBP3-21177 antibody. Corresponding AGER RNA-seq data are presented for the same tissues.
Staining of rat lung shows strong membranous positivity in pneumocytes.
Staining of human placenta shows no positivity in trophoblastic cells as expected.

Product Details

Summary
Reactivity Hu, Rt, MuSpecies Glossary
Applications IHC
Clone
CL10591
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated
Validated by:
       

Orthogonal Strategies

  

Order Details

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AGER Antibody (CL10591) Summary

Immunogen
This antibody was developed against a Synthetic Peptide of Q15109. Actual immunogen sequence is proprietary.
Predicted Species
Mouse (100%). Backed by our 100% Guarantee.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
AGER
Purity
Protein A purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
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Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:200 - 1:500
  • Immunohistochemistry-Paraffin 1:200 - 1:500
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS, pH 7.2, 40% glycerol
Preservative
0.02% Sodium Azide
Purity
Protein A purified

Alternate Names for AGER Antibody (CL10591)

  • advanced glycosylation end product-specific receptor
  • AGER
  • RAGE isoform delta
  • RAGE isoform sRAGE-delta
  • RAGE
  • Receptor for advanced glycosylation end products
  • receptor for advanced glycosylation end-products
  • SCARJ1

Background

AGER encodes a member of the immunoglobulin superfamily of cell surface molecules. It is a receptor for various molecules, including the amyloidogenic form of serum amyloid A, amyloid-beta protein, members of the S100/calgranulin superfamily and advanced glycation end products. The gene lies within the major histocompatibility complex (MHC) class III region on chromosome 6. Alternative splicing results in two transcript variants encoding different isoforms. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol AGER