AdipoR1 Antibody (2416C) [Unconjugated] Summary
Additional Information |
Recombinant Monoclonal Antibody. |
Immunogen |
Synthetic peptide containing human AdipoR1 C-term sequences
|
Specificity |
Detects human AdipoR1 in direct ELISAs. In direct ELISA, no cross-reactivity with human AdipoR2 is observed
|
Source |
N/A |
Isotype |
IgG1 |
Clonality |
Monoclonal |
Host |
Rabbit |
Purity Statement |
Protein A or G purified from cell culture supernatant |
Innovator's Reward |
Test in a species/application not listed above to receive a full credit towards a future purchase. |
Applications/Dilutions
Dilutions |
- CyTOF-ready
- Flow Cytometry 0.25 ug/10^6 cells
- Immunohistochemistry 3-25 ug/mL
|
Packaging, Storage & Formulations
Storage |
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. - 12 months from date of receipt, -20 to -70 °C as supplied.
- 1 month, 2 to 8 °C under sterile conditions after reconstitution.
- 6 months, -20 to -70 °C under sterile conditions after reconstitution.
|
Buffer |
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS. |
Reconstitution Instructions |
Reconstitute at 0.5 mg/mL in sterile PBS. |
Notes
This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.
Alternate Names for AdipoR1 Antibody (2416C) [Unconjugated]
Background
Adiponectin
receptor protein 1 (AdipoR1) is a 7 transmembrane receptor for globular and
full-length adiponectin required for normal glucose and fat homeostasis and for
maintaining a normal body weight.
AdipoR1 mediates increased AMP kinase and PPAR-alpha ligand activities
well as fatty-acid oxidation and glucose uptake by adiponectin. Genetic variability at the AdipoR1 locus is a
strong determinant of coronary artery disease susceptibility in type 2
diabetes. AdipoR1 is abundantly
expressed in skeletal muscle.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are
guaranteed for 1 year from date of receipt.
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