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AdipoR1 Antibody (2416C) [Unconjugated]

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HEK293 human embryonic kidney cell line transfected with either (A) human AdipoR1 or (B) irrelevant transfectants and eGFP was stained with Rabbit Anti-Human AdipoR1 Monoclonal Antibody (Catalog # MAB10128) followed by ...read more
AdipoR1 was detected in immersion fixed paraffin-embedded sections of human placenta using Rabbit Anti-Human AdipoR1 Monoclonal Antibody (Catalog # MAB10128) at 3 µg/mL for 1 hour at room temperature followed by ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow, IHC, CyTOF-ready
Clone
2416C
Clonality
Monoclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

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AdipoR1 Antibody (2416C) [Unconjugated] Summary

Additional Information
Recombinant Monoclonal Antibody.
Immunogen
Synthetic peptide containing human AdipoR1 C-term sequences
Specificity
Detects human AdipoR1 in direct ELISAs. In direct ELISA, no cross-reactivity with human AdipoR2 is observed
Source
N/A
Isotype
IgG1
Clonality
Monoclonal
Host
Rabbit
Purity Statement
Protein A or G purified from cell culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • CyTOF-ready
  • Flow Cytometry 0.25 ug/10^6 cells
  • Immunohistochemistry 3-25 ug/mL

Packaging, Storage & Formulations

Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Buffer
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Reconstitution Instructions
Reconstitute at 0.5 mg/mL in sterile PBS.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for AdipoR1 Antibody (2416C) [Unconjugated]

  • ACDCR1
  • adiponectin receptor 1
  • adiponectin receptor protein 1
  • AdipoR1
  • ADR1
  • CGI45
  • FLJ42464
  • PAQR1
  • PAQR1FLJ25385
  • Progestin and adipoQ receptor family member I
  • TESBP1A

Background

Adiponectin receptor protein 1 (AdipoR1) is a 7 transmembrane receptor for globular and full-length adiponectin required for normal glucose and fat homeostasis and for maintaining a normal body weight.  AdipoR1 mediates increased AMP kinase and PPAR-alpha ligand activities well as fatty-acid oxidation and glucose uptake by adiponectin.  Genetic variability at the AdipoR1 locus is a strong determinant of coronary artery disease susceptibility in type 2 diabetes.  AdipoR1 is abundantly expressed in skeletal muscle.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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