5-HT4 Antibody [DyLight 550]

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

The 5HT4 receptor (5-HT4R) is a member of the serotonin receptors. In response to serotonin (5HT) these G protein coupled receptors cause an increase in cAMP production. It is a glycosylated, transmembrane protein found in the central and peripheral nervous system. Multiple transcripts with variant C-terminal sequnces have been described. The significance of SNP variants of 5HT4 receptors in mental diseases is a controversial topic (PMID:19328558, 19892407), while other SNP variants have been associated with asthma.( PMID:21382128). Additional research show that the early presence of these receptors in the dorsomedial nuclei of prenatal hypothalamus may indicate a crucial role in fetal development. (PMID:20538346)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Array NBP1-78403R

• 5-HT4 Antibodies
• 5-HT4 ELISA Kits
• 5-HT4 Lysates
• 5-HT4 Proteins