Reactivity | HuSpecies Glossary |
Applications | Flow, IHC, CyTOF-ready |
Clone | 496214 |
Clonality | Monoclonal |
Host | Mouse |
Conjugate | Unconjugated |
Concentration | LYOPH |
Immunogen | NS0 mouse myeloma cell line transfected with human 5HT2C |
Specificity | Detects human 5HT2C in direct ELISAs. |
Source | N/A |
Isotype | IgG2a |
Clonality | Monoclonal |
Host | Mouse |
Gene | HTR2C |
Purity Statement | Protein A or G purified from hybridoma culture supernatant |
Innovator's Reward | Test in a species/application not listed above to receive a full credit towards a future purchase. |
Storage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
|
Buffer | Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS. |
Preservative | No Preservative |
Concentration | LYOPH |
Reconstitution Instructions | Reconstitute at 0.5 mg/mL in sterile PBS. |
5HT2C is a 45 kDa 7TM receptor for serotonin and is neuronally expressed in the limbic system of the brain. The release of dopamine due to 5HT2C ligation regulates mood, appetite, and motivation. 5HT2C is an important pharmacologic target in the treatment of psychosis, schizophrenia, depression, anxiety, and migrane headaches. Multiple isoforms of 5HT2C can be generated by RNA editing. Human 5HT2C shares 89% aa sequence identity with mouse and rat 5HT2C.
Secondary Antibodies |
Isotype Controls |
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Gene Symbol | HTR2C |