11 beta-HSD1 Antibody

The protein encoded by this gene is a microsomal enzyme that catalyzes the conversion of the stress hormone cortisol to the inactive metabolite cortisone. In addition, the encoded protein can catalyze the reverse reaction, the conversion of cortisone to cortisol. Too much cortisol can lead to central obesity, and a particular variation in this gene has been associated with obesity and insulin resistance in children. Two transcript variants encoding the same protein have been found for this gene.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publication using NB300-934	Applications	Species
Paterson JM, Morton NM, Fievet C et al. Metabolic syndrome without obesity: Hepatic overexpression of 11beta-hydroxysteroid dehydrogenase type 1 in transgenic mice. Proc Natl Acad Sci U S A 2004-05-04 [PMID: 15118095]

Array NB300-934

• 11 beta-HSD1 Antibodies
• 11 beta-HSD1 ELISA Kits
• 11 beta-HSD1 Lysates
• 11 beta-HSD1 Proteins