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TXNIP Antibody (JY2) [Janelia Fluor® 549]

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Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB, Flow, Func, IHC, IP, CyTOF-ready, KO
Clone
JY2
Clonality
Monoclonal
Host
Mouse
Conjugate
Janelia Fluor 549

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TXNIP Antibody (JY2) [Janelia Fluor® 549] Summary

Immunogen
Human recombinant TXNIP
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
TXNIP
Purity
Protein A or G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • CyTOF-ready
  • Flow Cytometry
  • Immunohistochemistry
  • Immunohistochemistry-Frozen
  • Immunohistochemistry-Paraffin
  • Immunoprecipitation
  • Knockout Validated
  • Proximity Ligation Assay
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

Use in Mouse reported in scientific literature (PMID:34576095). Please note that this antibody is reactive to Mouse and derived from the same host, Mouse. Additional Mouse on Mouse blocking steps may be required for IHC and ICC experiments. Please contact Technical Support for more information.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified

Notes

Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for TXNIP Antibody (JY2) [Janelia Fluor® 549]

  • HHCPA78
  • THIF
  • thioredoxin binding protein 2
  • thioredoxin interacting protein
  • Thioredoxin-binding protein 2
  • thioredoxin-interacting protein
  • upregulated by 1,25-dihydroxyvitamin D-3
  • VDUP1EST01027
  • Vitamin D3 up-regulated protein 1

Background

TXNIP may act as an oxidative stress mediator by inhibiting thioredoxin activity or by limiting its bioavailability. Interacts with COPS5 and restores COPS5-induced suppressionof CDKN1B stability, blocking the COPS5-mediated translocation of CDKN1B from the nu

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Video Protocols

WB Video Protocol

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Bioinformatics

Gene Symbol TXNIP