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Tryptophanyl tRNA synthetase Antibody (1C6K8)

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications ELISA, IHC
Clone
1C6K8
Clonality
Monoclonal
Host
Rabbit
Conjugate
Unconjugated

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Tryptophanyl tRNA synthetase Antibody (1C6K8) Summary

Immunogen
A synthetic peptide corresponding to a sequence within amino acids 372-471 of human Tryptophanyl tRNA synthetase (P23381).

Sequence:
VNKHAFSGGRDTIEEHRQFGGNCDVDVSFMYLTFFLEDDDKLEQIRKDYTSGAMLTGELKKALIEVLQPLIAEHQARRKEVTDEIVKEFMTPRKLSFDFQ
Isotype
IgG
Clonality
Monoclonal
Host
Rabbit
Gene
WARS
Purity
Affinity purified
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Applications/Dilutions

Dilutions
  • ELISA Recommended starting concentration is 1 ug/mL
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin 1:50 - 1:200
Theoretical MW
53 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.3), 50% glycerol, 0.05% BSA
Preservative
0.02% Sodium Azide
Purity
Affinity purified

Alternate Names for Tryptophanyl tRNA synthetase Antibody (1C6K8)

  • EC 6.1.1
  • EC 6.1.1.2
  • GAMMA-2
  • hWRS
  • IFI53
  • IFP53trpRS
  • Interferon-induced protein 53
  • TrpRS
  • tryptophan tRNA ligase 1, cytoplasmic
  • Tryptophan--tRNA ligase
  • tryptophanyl-tRNA synthetase
  • tryptophanyl-tRNA synthetase, cytoplasmic
  • WRS

Background

Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Two forms of tryptophanyl-tRNA synthetase exist, a cytoplasmic form, named WARS, and a mitochondrial form, named WARS2. Tryptophanyl-tRNA synthetase (WARS) catalyzes the aminoacylation of tRNA(trp) with tryptophan and is induced by interferon. Tryptophanyl-tRNA synthetase belongs to the class I tRNA synthetase family. Four transcript variants encoding two different isoforms have been found for this gene.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol WARS