E. coli-derived recombinant human KLF6 Met1-Ser109 Accession # Q99612
Specificity
Detects human KLF6 in direct ELISAs and Western blots. In direct ELISAs and Western blots, this antibody shows less than 5% cross‑reactivity with rhKLF4, rhKLF5 and rmKLF15.
Source
N/A
Isotype
IgG
Clonality
Polyclonal
Host
Sheep
Gene
KLF6
Purity Statement
Antigen Affinity-purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70 °C as supplied.
1 month, 2 to 8 °C under sterile conditions after reconstitution.
6 months, -20 to -70 °C under sterile conditions after reconstitution.
Buffer
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Preservative
No Preservative
Concentration
LYOPH
Reconstitution Instructions
Reconstitute at 0.2 mg/mL in sterile PBS.
Notes
This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.
Alternate Names for KLF6 Antibody
BCD1
BCD1Zf9
B-cell-derived protein 1
COPEB
COPEBCBA1
core promoter element binding protein
Core promoter element-binding protein
CPBP
CPBPZF9
DKFZp686N0199
EC 2.1.1.43
EC 6.1.1.15
GBF
GC-rich binding factor
GC-rich sites-binding factor GBF
KLF6
Krueppel-like factor 6
Kruppel-like factor 6
Kruppel-like zinc finger protein Zf9
PAC1
Proto-oncogene BCD1
protooncogene B-cell derived 1
ST12
suppression of tumorigenicity 12 (prostate)
Suppressor of tumorigenicity 12 protein
Transcription factor Zf9
Background
KLF6 is a ubiquitously expressed nuclear protein belonging to the Kruppel C2H2-type zinc finger transcription factor family. It is a 283 amino acid (aa) protein that contains an N-terminal acidic domain, a Ser/Thr-rich region and three zinc-finger motifs. The acidic region may interact with other transcription factors. The Ser-Thr-rich region likely serves as an activation domain, and the zinc-finger motifs bind DNA. One alternate splice form is known that shows a 55 aa substitution for the C‑terminal 57 amino acids. KLF6 is considered a tumor-suppressor gene. It also promotes iNOS and TGF-beta 1 expression. Human KLF6 shares 94%, 95% and 94% aa sequence identity with rat, mouse and canine KLF6, respectively.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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