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Tryptase alpha/beta 1 Antibody [Biotin]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB
Clonality
Polyclonal
Host
Goat
Conjugate
Biotin
Concentration
LYOPH

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Tryptase alpha/beta 1 Antibody [Biotin] Summary

Immunogen
Mouse myeloma cell line NS0-derived recombinant human Tryptase alpha /TPS1
Ile31-Pro275
Accession # AAA86934
Specificity
Detects human Tryptase alpha /TPS1 in Western blots. In Western blots, approximately 60% cross-reactivity with recombinant human (rh) TPSB2 is observed and approximately 10% cross-reactivity with rhTPSG1 is observed.
Source
N/A
Isotype
IgG
Clonality
Polyclonal
Host
Goat
Gene
TPSAB1
Purity Statement
Antigen Affinity-purified
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Applications/Dilutions

Packaging, Storage & Formulations

Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Buffer
Lyophilized from a 0.2 μm filtered solution in PBS with BSA as a carrier protein.
Preservative
No Preservative
Concentration
LYOPH
Reconstitution Instructions
Reconstitute at 0.2 mg/mL in sterile PBS.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Tryptase alpha/beta 1 Antibody [Biotin]

  • alpha-Tryptase
  • EC:3.4.21.59
  • epididymis secretory sperm binding protein
  • mast cell alpha II tryptase
  • mast cell beta I tryptase
  • mast cell tryptase
  • TPS1
  • TPS2
  • TPSAB1
  • TPSB1
  • TPSB2
  • Tryptase 1
  • tryptase alpha II
  • Tryptase alpha
  • Tryptase alpha-1
  • tryptase beta I
  • tryptase beta-1
  • Tryptase beta-2
  • Tryptase I
  • tryptase II
  • tryptase-1
  • tryptase-2
  • tryptase-I
  • tryptase-III

Background

Tryptases are serine proteases with trypsin-like specificity. Together with chymases and Cathepsin G, tryptases are important players in mast cell mediation of inflammatory and allergic responses. Tryptase beta-1, also known as mast cell protease 7 (MCPT7), exhibits anticoagulant activity due to its ability to degrade fibrinogen in the presence of a diverse array of protease inhibitors in plasma. Tryptase epsilon, also known as brain-specific serine protease 4 (BSSP-4) and brain serine protease 2 (BSP-2), is encoded by the PRSS22 gene and preferentially expressed in epithelium-rich tissues such as lung and eye. Tryptase gamma-1, also called transmembrane tryptase, is encoded by TPSG1, one of many serine protease genes clustered on human chromosome 16p13.3.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol TPSAB1
Uniprot