TREX1 Antibody

This product is produced by and distributed for Abnova, a company based in Taiwan.

This gene encodes the major 3'->5' DNA exonuclease in human cells. The protein is a non-processive exonuclease that may serve a proofreading function for a human DNA polymerase. It is also a component of the SET complex, and acts to rapidly degrade 3' ends of nicked DNA during granzyme A-mediated cell death. Mutations in this gene result in Aicardi-Goutieres syndrome, chilblain lupus, and Cree encephalitis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 1 confirmed species: Human.

Showing Publications 1 - 2 of 2.

Publications using H00011277-D01P	Applications	Species
Tomicic MT, Aasland D, Nikolova T et al. Human three prime exonuclease TREX1 is induced by genotoxic stress and involved in protection of glioma and melanoma cells to anticancer drugs. Biochim Biophys Acta. 2013-08-01 [PMID: 23578789] (Human)		Human
Christmann M, Tomicic MT, AaslD et al. Three prime exonuclease I (TREX1) is Fos/AP-1 regulated by genotoxic stress and protects against ultraviolet light and benzo(a)pyrene-induced DNA damage. Nucleic Acids Res. 2010-05-28 [PMID: 20511593]

Array H00011277-D01P

• TREX1 Antibodies
• TREX1 Lysate
• TREX1 Proteins