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TR2/NR2C1 Antibody

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Orthogonal Strategies: Immunohistochemistry-Paraffin: TR2/NR2C1 Antibody [NBP2-56277] - Staining in human testis and liver tissues using anti-NR2C1 antibody. Corresponding NR2C1 RNA-seq data are presented for the ...read more
Immunohistochemistry-Paraffin: TR2/NR2C1 Antibody [NBP2-56277] - Staining of human liver shows low expression as expected.
Immunohistochemistry-Paraffin: TR2/NR2C1 Antibody [NBP2-56277] - Staining of human testis shows high expression.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Validated by:
       

Orthogonal Strategies

 

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TR2/NR2C1 Antibody Summary

Immunogen
This antibody was developed against a recombinant protein corresponding to the following amino acid sequence: QFILTNHDGSTPSKVILARQDSTPGKVFLTTPDAAGVNQLFFTTPDLSAQHLQLLTDNSPDQGPNKV
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
NR2C1
Purity
Affinity purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:1000 - 1:2500
  • Immunohistochemistry-Paraffin 1:1000 - 1:2500
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Control Peptide
TR2/NR2C1 Recombinant Protein Antigen (NBP2-56277PEP)

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Affinity purified

Alternate Names for TR2/NR2C1 Antibody

  • NR2C1
  • nuclear receptor subfamily 2 group C member 1
  • nuclear receptor subfamily 2, group C isoform
  • nuclear receptor subfamily 2, group C, member 1
  • Orphan nuclear receptor TR2
  • Testicular receptor 2
  • TR2 nuclear hormone receptor
  • TR2
  • TR2-11

Background

NR2C1 encodes a nuclear hormone receptor characterized by a highly conserved DNA binding domain (DBD), a variable hinge region, and a carboxy-terminal ligand binding domain (LBD) that is typical for all members of the steroid/thyroid hormone receptor superfamily. This protein also belongs to a large family of ligand-inducible transcription factors that regulate gene expression by binding to specific DNA sequences within promoters of target genes. Multiple alternatively spliced transcript variants have been described, but the full-length nature of some of these variants has not been determined. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol NR2C1