TM4SF4 Antibody (832441) [Unconjugated]

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

TM4SF4 (transmembrane 4 L6 family member 4), also known as IL-TMP (intestine and liver tetraspanin membrane protein) is a member of the L6 tetraspanin family of molecules. It is expressed at highest levels on non-proliferating villus-associated intestinal epithelia and periportal hepatocytes, with increased expression in hepatocellular carcinomas. It is thought to mediate proliferation and adhesion. Its molecular size is reported at approximately 21 kDa for the unglycosylated form and 25-40 kDa for various glycosylated forms.  The 202 amino acid (aa) human TM4SF4 contains four transmembrane domains and two potential N-glycosylation sites. It shares 88% aa sequence identity with mouse and rat TM4SF4.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Showing Publications 1 - 2 of 2.

Publications using MAB7998	Applications	Species
Verena van der Heide, Sonia Jangra, Phillip Cohen, Raveen Rathnasinghe, Sadaf Aslam, Teresa Aydillo et al. Limited extent and consequences of pancreatic SARS-CoV-2 infection Cell Reports 2022-03-01 [PMID: 35247306]
Kyungsoo Jung, Joon-Seok Choi, Beom-Mo Koo, Yu Jin Kim, Ji-Young Song, Minjung Sung et al. TM4SF4 and LRRK2 Are Potential Therapeutic Targets in Lung and Breast Cancers through Outlier Analysis Cancer Research and Treatment 2021-01-15 [PMID: 32972043]

Array MAB7998

• TM4SF4 Antibodies
• TM4SF4 Lysate
• TM4SF4 Protein