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Thyroid Peroxidase Antibody (rTPO/7248) - Azide and BSA Free

Images

 
Formalin-fixed, paraffin-embedded human thyroid carcinoma stained with Thyroid Peroxidase antibody (rTPO/7248). Inset: PBS instead of primary antibody; secondary only negative control.
Formalin-fixed, paraffin-embedded human Ovarian Carcinoma stained with TGF beta Mouse Monoclonal Antibody (1D11.16.8).
Formalin-fixed, paraffin-embedded human Salivary Gland Carcinoma stained with TGF beta Mouse Monoclonal Antibody (1D11.16.8).

Product Details

Summary
Reactivity HuSpecies Glossary
Applications IHC
Clone
rTPO/7248
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated
Format
Azide and BSA Free
Concentration
1 mg/ml

Thyroid Peroxidase Antibody (rTPO/7248) - Azide and BSA Free Summary

Description
Positive Controls: Human thyroid carcinoma.

Antibody with azide - store at 2 to 8C. Antibody without azide - store at -20 to -80C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Additional Information
Recombinant Monoclonal Antibody
Immunogen
Recombinant fragment of human Thyroid Peroxidase (exact sequence is proprietary)
Localization
Cytoplasm. Cell surface.
Isotype
IgG1 Kappa
Clonality
Monoclonal
Host
Mouse
Gene
TPO
Purity
Protein A or G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry-Paraffin 1-2 ug/ml
Application Notes
Immunohistochemistry (Formalin-fixed): 1-2ug/ml for 30 minutes. at RT. Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95C followed by cooling at RT for 20 minutes.

Optimal dilution for a specific application should be determined.

Packaging, Storage & Formulations

Storage
Store at -20 to -70C. Avoid freeze-thaw cycles.
Buffer
10mM PBS
Preservative
No Preservative
Concentration
1 mg/ml
Purity
Protein A or G purified

Alternate Names for Thyroid Peroxidase Antibody (rTPO/7248) - Azide and BSA Free

  • EC 1.11.1
  • MSA
  • TDH2A
  • thyroid microsomal antigen
  • thyroid peroxidase
  • thyroperoxidase
  • TPXEC 1.11.1.8

Background

Thyroid Peroxidase encodes a membrane-bound glycoprotein. The encoded protein acts as an enzyme and plays a central role in thyroid gland function. The protein functions in the iodination of tyrosine residues in thyroglobulin and phenoxy-ester formation between pairs of iodinated tyrosines to generate the thyroid hormones, thyroxine and triiodothyronine. Mutations in this gene are associated with several disorders of thyroid hormonogenesis, including congenital hypothyroidism, congenital goiter, and thyroid hormone organification defect IIA. Multiple transcript variants encoding distinct isoforms have been identified for this gene. Additional splice variants have been described but their biological natures have not been determined. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol TPO