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TDP-43/TARDBP [p Ser409, p Ser410] Antibody - Azide and BSA Free

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Dot Blot: TDP-43/TARDBP [p Ser409, p Ser410] Antibody [NBP3-16952] - Dot-blot analysis of all sorts of peptides using TDP-43/TARDBP antibody (NBP3-16952) at 1:1000 dilution. Exposure time: 10s.
Dot Blot: TDP-43/TARDBP [p Ser409, p Ser410] Antibody [NBP3-16952] - Dot-blot analysis of all sorts of peptides using TDP-43/TARDBP antibody (NBP3-16952) at 1:1000 dilution. Exposure time: 1s.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, DB, ELISA
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Format
Azide and BSA Free

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TDP-43/TARDBP [p Ser409, p Ser410] Antibody - Azide and BSA Free Summary

Immunogen
A synthetic phosphorylated peptide around S409 & S410 of human TDP-43/TARDBP (NP_031401.1). SKSSGW
Modification
p Ser409, p Ser410
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
TARDBP
Purity
Affinity purified
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Applications/Dilutions

Dilutions
  • Dot Blot 1:500 - 1:1000
  • ELISA
  • Western Blot 1:500 - 1:2000

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
PBS, 50% glycerol, pH7.3
Preservative
0.05% Proclin 300
Purity
Affinity purified

Alternate Names for TDP-43/TARDBP [p Ser409, p Ser410] Antibody - Azide and BSA Free

  • ALS10
  • ALS10TAR DNA-binding protein-43
  • TAR DNA binding protein
  • TARDBP
  • TDP43
  • TDP-43
  • TDP-43TAR DNA-binding protein 43

Background

TARDBP, also known as TAR DNA binding protein, is a DNA and RNA-binding protein which regulates transcription and splicing. TARDBP is also involved in the regulation of CFTR splicing and promotes CFTR exon 9 skipping by binding to the UG repeated motifs in the polymorphic region near the 3'-splice site of this exon. The resulting aberrant splicing is associated with pathological features typical of cystic fibrosis. TARD-BP may also be involved in microRNA biogenesis, apoptosis and cell division. TARDBP can repress HIV-1 transcription by binding to the HIV-1 long terminal repeat.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol TARDBP