TDP-43/TARDBP [p Ser409, p Ser410] Antibody - Azide and BSA Free Summary
Immunogen |
A synthetic phosphorylated peptide around S409 & S410 of human TDP-43/TARDBP (NP_031401.1). SKSSGW |
Modification |
p Ser409, p Ser410 |
Isotype |
IgG |
Clonality |
Polyclonal |
Host |
Rabbit |
Gene |
TARDBP |
Purity |
Affinity purified |
Innovator's Reward |
Test in a species/application not listed above to receive a full credit towards a future purchase. |
Applications/Dilutions
Dilutions |
- Dot Blot 1:500 - 1:1000
- ELISA
- Western Blot 1:500 - 1:2000
|
Packaging, Storage & Formulations
Storage |
Store at -20C. Avoid freeze-thaw cycles. |
Buffer |
PBS, 50% glycerol, pH7.3 |
Preservative |
0.05% Proclin 300 |
Purity |
Affinity purified |
Alternate Names for TDP-43/TARDBP [p Ser409, p Ser410] Antibody - Azide and BSA Free
Background
TARDBP, also known as TAR DNA binding protein, is a DNA and RNA-binding protein which regulates transcription and splicing. TARDBP is also involved in the regulation of CFTR splicing and promotes CFTR exon 9 skipping by binding to the UG repeated motifs in the polymorphic region near the 3'-splice site of this exon. The resulting aberrant splicing is associated with pathological features typical of cystic fibrosis. TARD-BP may also be involved in microRNA biogenesis, apoptosis and cell division. TARDBP can repress HIV-1 transcription by binding to the HIV-1 long terminal repeat.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are
guaranteed for 1 year from date of receipt.
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FAQs for TDP-43/TARDBP Antibody (NBP3-16952) (0)
Secondary Antibodies
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Isotype Controls
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