TDP-43/TARDBP Antibody

TARDBP, also known as TAR DNA binding protein, is a DNA and RNA-binding protein which regulates transcription and splicing. TARDBP is also involved in the regulation of CFTR splicing and promotes CFTR exon 9 skipping by binding to the UG repeated motifs in the polymorphic region near the 3'-splice site of this exon. The resulting aberrant splicing is associated with pathological features typical of cystic fibrosis. TARD-BP may also be involved in microRNA biogenesis, apoptosis and cell division. TARDBP can repress HIV-1 transcription by binding to the HIV-1 long terminal repeat.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Showing Publications 1 - 3 of 3.

Publications using NBP1-89116	Applications	Species
Tyleckova J, Hrabakova R, Mairychova K et al. Cancer Cell Response to Anthracyclines Effects: Mysteries of the Hidden Proteins Associated with These Drugs. Int J Mol Sci 2012-11-22 [PMID: 23443080]
Stadler C, Rexhepaj E, Singan VR et al. Immunofluorescence and fluorescent-protein tagging show high correlation for protein localization in mammalian cells. Nat Methods 2013-04-01 [PMID: 23435261]
Sharma M, Burre J, Sudhof TC et al. CSP? promotes SNARE-complex assembly by chaperoning SNAP-25 during synaptic activity. Nat Cell Biol 2011-01-01 [PMID: 21151134]

Array NBP1-89116

• TDP-43/TARDBP Antibodies
• TDP-43/TARDBP ELISA Kits
• TDP-43/TARDBP Lysate
• TDP-43/TARDBP Proteins
• TDP-43/TARDBP Proteins and Enzyme